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Genomics

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Pubudu Gokarella

this is done by me and my team mates of Wayamba University Sri Lanka for our project.From now we decided to allow download this file.I would be greatful if you could send your comments.. And I'm willing to help you in similar works.I'm in final year of my degree(.BSc Biotechnology).. pubudu_gokarella@yahoo.com

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GENOMICS
WHAT IS GENOMICS? ,[object Object],[object Object],[object Object],[object Object],[object Object]
WHAT IS GENOMICS? ,[object Object]
WHAT IS GENOMICS? ,[object Object],[object Object],[object Object]
HISTORY OF GENOMICS ,[object Object],[object Object]
[object Object],[object Object],HISTORY OF GENOMICS cont…
RELATED DEVELOPMENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
WHAT IS A GENOME? ,[object Object],[object Object]
WHAT IS A GENOME? ,[object Object],[object Object],[object Object]
[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
LOOKING AT A GENOME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SOME QUICK FACTS ABOUT GENOMES ,[object Object],[object Object]
QUICK FACTS cont… ,[object Object],[object Object],[object Object]
QUICK FACTS cont… ,[object Object],[object Object],[object Object]
Genes and Proteins & the role of Introns ,[object Object],[object Object],[object Object],[object Object]
INTRONS AND EXONS
INTRONS AND EXONS ,[object Object],[object Object]
INTRONS AND EXONS ,[object Object],[object Object],[object Object]
[object Object],[object Object]
WHY SEQUENCE GENOMES? ,[object Object],[object Object]
WHY SEQUENCE GENOMES? ,[object Object],[object Object]
WHY SEQUENCE GENOMES? ,[object Object],[object Object]
WHY SEQUENCE GENOMES? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ANTICIPATED BENEFITS OF GENOME RESEARCH ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GENOME MAPPING ,[object Object],[object Object],[object Object],[object Object]
LINKAGE MAP ,[object Object],[object Object]
RESTRICTION CLEAVAGE ,[object Object],[object Object]
DNA SEQUENCE ,[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object],[object Object],[object Object]
HUMAN GENOME PROJECT ,[object Object],[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object]
A CLOSER LOOK AT THE HUMAN GENOME
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object],[object Object]
A CLOSER LOOK AT THE HUMAN GENOME ,[object Object],[object Object]
SEQUENCING THE GENOMES OF OTHER ORGANISMS ,[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object]
PROKARYOTIC GENOMES ,[object Object],[object Object],[object Object],[object Object]
Escherichia coli Genome ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object]
Escherichia coli Genome ,[object Object],[object Object],[object Object],[object Object],[object Object]
EUKARYOTIC GENOMES ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Arabidopsis thaliana (Thale / Mouse Ear Cress) Genome ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
46022 – 55615 466 Mb Rice Oryza sativa ssp .japonica 32 – 50000 420 Mb Rice Oryza sativa ssp. indica Number of genes predicted Genome size Type Organism
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
COMPARING THE GENOMES OF DIFFERENT ORGANISMS ,[object Object],[object Object],[object Object],[object Object],[object Object]
COMPARATIVE CEREAL GENOMICS ,[object Object],[object Object],[object Object]
COMPARATIVE CEREAL GENOMICS ,[object Object],[object Object]
COMPARATIVE CEREAL GENOMICS
COMPARATIVE CEREAL GENOMICS ,[object Object],[object Object],[object Object],[object Object]
COMPARATIVE CEREAL GENOMICS ,[object Object],[object Object],[object Object],[object Object]
COMPARATIVE ANALYSIS OF THE HUMAN AND MOUSE GENOMES ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
GENERAL GENOMIC COMPARISONS ,[object Object],[object Object]
GENERAL GENOMIC COMPARISONS 9 9700 Human immunodeficiency virus (HIV) 3,200 4.6 million Bacterium ( E. coli ) 6,000 12.1 million Yeast ( S. cerevisiae ) 13,000 137 million Fruit fly ( D. melanogaster ) 19,000 97 million Roundworm ( C. elegans ) 25,000 100 million Thale cress ( A. thaliana ) 30,000 2.6 billion Laboratory mouse ( M. musculus ) 30,000 3 billion Human ( Homo sapiens ) Estimated Genes Genome Size (Bases) Organism
 
GENOMES AND EVOLUTION ,[object Object],[object Object]
GENOMES AND EVOLUTION ,[object Object]
 
GENOMES AND EVOLUTION ,[object Object]
GENOMES AND EVOLUTION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
ISSUES OF CONCERN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ISSUES OF CONCERN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ISSUES OF CONCERN ,[object Object],[object Object],[object Object],[object Object]
ISSUES OF CONCERN ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object]
ISSUES OF CONCERN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THE FUTURE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THE FUTURE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THE FUTURE ,[object Object],[object Object],[object Object],[object Object],[object Object]
THE FUTURE Genomes to Life: A DOE Systems Biology Program Exploring Microbial Genomes for Energy and the Environment Chart genetic variation within the human genome HapMap
THE FUTURE ,[object Object],[object Object],[object Object]
THE FUTURE ,[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Thank You ! ,[object Object],[object Object],[object Object],[object Object]
REFERENCES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Genomics

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  • 47. A CLOSER LOOK AT THE HUMAN GENOME
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  • 49. A CLOSER LOOK AT THE HUMAN GENOME
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  • 71. 46022 – 55615 466 Mb Rice Oryza sativa ssp .japonica 32 – 50000 420 Mb Rice Oryza sativa ssp. indica Number of genes predicted Genome size Type Organism
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  • 83. GENERAL GENOMIC COMPARISONS 9 9700 Human immunodeficiency virus (HIV) 3,200 4.6 million Bacterium ( E. coli ) 6,000 12.1 million Yeast ( S. cerevisiae ) 13,000 137 million Fruit fly ( D. melanogaster ) 19,000 97 million Roundworm ( C. elegans ) 25,000 100 million Thale cress ( A. thaliana ) 30,000 2.6 billion Laboratory mouse ( M. musculus ) 30,000 3 billion Human ( Homo sapiens ) Estimated Genes Genome Size (Bases) Organism
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  • 102. THE FUTURE Genomes to Life: A DOE Systems Biology Program Exploring Microbial Genomes for Energy and the Environment Chart genetic variation within the human genome HapMap
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