7. If 1 L of solute-free water is lost from the body, how
much fluid is lost by the ICF compartment?
7
Water ICF : ECF = 2:1 ratio
Solute-free water loss
Twofold greater reduction in the ICF compartment
than the ECF compartment
Volume loss
ICF = 667 mL
ECF = 333 mL
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8. Lose of 1L of iso-osmotic fluid
8
ECF compartment will decrease by 1 L
Na+ is largely restricted to the ECF
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9. Osmolality and osmolarity
9
Often used interchangeably
Osmolality
Number of solutes per mass of water
Osmolarity
Number of moles of solute in a liter of solution
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10. Solutes
10
Extracellular and intracellular solutes (or
osmoles)
Markedly different
Water
Moves across cell membranes
Distributes between ICF and ECF
Until the osmolality is the same
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