DNA fingerprints

1. DNA IN FORENSIC MEDICINE
By
Rasha El-haddad Ali Mossa
Demonstrator of forensic medicine and clinical toxicology

2. INTRODUCTION
Alec Jefferys

3. CELL BIOLOGY

4. DNA IDENTIFICATION SYSTEMS
 RFLP
 SNP
 VNTR
 STR
 Y-STR
 Mitochondrial DNA

5. RFLP

7. SNP

8. VNTR & STR

10. STEPS OF DNA PROFILING
1. Sample identification
2. DNA extraction
3. PCR

11. 4. Analysis

12. 5. Interpretation

13. ADVANCES IN DNA PROFILING
 New loci
 Non invasive prenatal paternity test
 Y-str
 Mitochondrial DNA analysis

14. RNA
 Identification of cell specific mRNA
expression from body fluids adds a new
dimension to forensic DNA analysis.
 determination of a specific disease or
mechanisms that lead to death.
 determination of wound age and time passed
since death

15. EPIGENETICS
 DNA methylation, histon modification
 It may be the only way to distinguish DNA of
identical twins
 only way to detect artificial DNA