1. EDWARD SYNDROME

2. EDWARD SYNDROME
 Also called TRISOMY 18

3. EDWARD SYNDROME
 Also called TRISOMY 18
 ES is a chromosomal condition associated with abnormalities
in many parts of the body. It result from having three copies
of chromosome 18 instead of the usual two copies

4. EDWARD SYNDROME
 Also called TRISOMY 18
 ES is a chromosomal condition associated with abnormalities
in many parts of the body. It result from having three copies
of chromosome 18 instead of the usual two copies
 It is named after John H. Edwards, who first described the
syndrome in 1960

5. EDWARD SYNDROME
 Also called TRISOMY 18
 ES is a chromosomal condition associated with abnormalities
in many parts of the body. It result from having three copies
of chromosome 18 instead of the usual two copies
 It is named after John H. Edwards, who first described the
syndrome in 1960
 ES occurs in around 1 in 6,000 live births and around 80% of
those af fected are female

6. EDWARD SYNDROME
 The incidence increases as the mother's age increases

7. EDWARD SYNDROME
 The incidence increases as the mother's age increases
 The syndrome has a very low rate of sur vival.

8. EDWARD SYNDROME
 The incidence increases as the mother's age increases
 The syndrome has a very low rate of sur vival.
 Most cases of trisomy 18 are not inherited, but occur as
random events during the formation of eggs and sperm. An
error in cell division called nondisjunction results in a
reproductive cell with an abnormal number of chromosomes

9. SYMPTOMS

10. EDWARD SYNDROME: SYMPTOMS
 Appear both fragile and weak; many are under weight.

11. EDWARD SYNDROME: SYMPTOMS
 Appear both fragile and weak; many are under weight.
 Their heads are unusually small

12. EDWARD SYNDROME: SYMPTOMS
 Appear both fragile and weak; many are under weight.
 Their heads are unusually small
 Their ears are low -set and malformed, and their mouths and
jaws are small

13. EDWARD SYNDROME: SYMPTOMS
 Appear both fragile and weak; many are under weight.
 Their heads are unusually small
 Their ears are low -set and malformed, and their mouths and
jaws are small
 Babies with the syndrome may experience a clef t palate or lip

14. EDWARD SYNDROME: SYMPTOMS
 Appear both fragile and weak; many are under weight.
 Their heads are unusually small
 Their ears are low -set and malformed, and their mouths and
jaws are small
 Babies with the syndrome may experience a clef t palate or lip
 Hands are often clenched into fists, with their index finger
overlapping their other fingers

15. EDWARD SYNDROME: SYMPTOMS
 Children with the syndrome can experience problems with
their lungs and diaphragm, and blood vessels which are
malformed.

16. EDWARD SYNDROME: SYMPTOMS
 Children with the syndrome can experience problems with
their lungs and diaphragm, and blood vessels which are
malformed.
 They may present with a number of types of congenital heart
disease.

17. EDWARD SYNDROME: SYMPTOMS
 Children with the syndrome can experience problems with
their lungs and diaphragm, and blood vessels which are
malformed.
 They may present with a number of types of congenital heart
disease.
 They might also have an umbilical hernia, abnormalities of
their urogenital system, malformed kidneys, or undescended
testicles if they are male.

21. TREATMENT

22. EDWARD SYNDROME: TREATMENT
 Medical science has not found a cure for Edward's syndrome
at this time.
 Babies with the syndrome commonly present with major
physical abnormalities and doctors face hard choices in
regards to their treatment

23. EDWARD SYNDROME: TREATMENT
 Medical science has not found a cure for Edward's syndrome
at this time.
 Babies with the syndrome commonly present with major
physical abnormalities and doctors face hard choices in
regards to their treatment.
 Surgery can treat some of the issues related to the syndrome,
yet extreme and invasive procedures might not be in the best
interests of an infant whose lifespan could be measured in
weeks or even days.

24. EDWARD SYNDROME: TREATMENT
 Medical science has not found a cure for Edward's syndrome
at this time.
 Babies with the syndrome commonly present with major
physical abnormalities and doctors face hard choices in
regards to their treatment.
 Surgery can treat some of the issues related to the
syndrome, yet extreme and invasive procedures might not be
in the best interests of an infant whose lifespan could be
measured in weeks or even days.
 Treatment today consists of palliative care

25. PROGNOSIS

26. EDWARD SYNDROME: PROGNOSIS
 The majority of children who are born with Edward's syndrome
do not live past their first year of life. A pproximately 90 to
95% of these children die prior to their first birthday. The 5 -
10% of children who do survive their first year experience
severe developmental disabilities.

27. EDWARD SYNDROME: PROGNOSIS
 The majority of children who are born with Edward's syndrome
do not live past their first year of life. Approximately 90 to
95% of these children die prior to their first birthday. The 5 -
10% of children who do survive their first year experience
severe developmental disabilities.
 Children who live past their first year require walking support
and their ability to learn is limited. Their verbal
communication abilities are limited as well, although they are
able to respond to comforting and have the ability to learn to
smile, recognize and interact with caregivers and others.

28. THANK YOU!