Bio::Phylo is a BioPerl-compatible phyloinformatics toolkit that implements EvoIO concepts and technologies. It can be used for phyloinformatics workflows and data transformation, PhyloWS servers and clients, visualization, and analysis and simulation of tree shapes. Future directions include tighter integration with BioPerl, extending PhyloWS functionality, and SWIG backends for other tools like HyPhy, NCL, and Beagle.