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PRESENTED BY:
(DR.) VISHNU.R.NAIR,
PHARM.D INTERN(AMRI HOSPITAL ACADEMIC TRAINEE),
NATIONAL COLLEGE OF PHARMACY, KOZHIKODE, KERALA.
 Pharmacology  one of the most difficult subjects in medical science!
 Along with newer drugs that get approved each year  remembering the older ones 
poses a significant impediment in the path of smooth memory!
 Use of easy-to-remember mnemonics  helps in the following:
- Easy interpretation
- Easy memorizing
- Contributes to smart work!
 Hence this powerpoint  aims at presenting some clinically relevant drug mnemonics, that
may be worthwhile for some!
HAPPY READING!!
GENERAL PHARMACOLOGY
To remember the names of drugs that undergo first-pass metabolism
Remember the code: “Nitrates Have Large Pre Systemic Metabolism”
Nitrates
Morphine
Salbutamol
Propranolol
Lignocaine
Hydrocortiso
ne
To remember the relevance of protein binding of drug
Remember the code “DDDD(4D)”
PPB: Plasma protein binding.
Duration of action:
Drugs with high PPB
 Long-acting!
Dialysis:
Drugs with high PPB
 Can’t be
removed by dialysis!
Displacement:
A high PPB drug 
can displace
another high PPB
drug!
Distribution:
Drugs with high
PPB  stay in
plasma  low
distribution!
To remember the names of drugs, which cannot be eliminated by dialysis
Remember the code “AVOID Dialysis”
Amphetamines
Digitalis
Imipramine
Diazepam
Organophosph
ates, opioids
Verapamil
To remember the names of prodrugs
Remember the code: “All Prefer Doing MD In Clinical Subjects”
*Except captopril & lisinopril
ACE-
inhibitors*
Sulfasalazine
Cyclophosphamide,
carbimazole, clopidogrel
Irinotecan,
INH
Dopamine
precursor(L-
dopa)
Mercaptopurine
, Methyldopa,
Minoxidil
Dipivefrine
Prednisone,
Proguanil,
PPIs
To remember the names of drugs/substances that are enzyme inducers
Remember the code: “GPRS Cell Phone”
*Carbamazepine
Griseofulvin
CBZ*
Phenobarbitone
Smoking(Nic
otine)Rifampicin
Phenytoin
To remember the names of drugs that cause enzyme inhibition
Remember the code: “Vitamin K Cannot Cause Enzyme Inhibition”
*Isoniazid
Valproate
Ketoconazole
INH*
ErythromycinCiprofloxacin
Cimetidine
To remember the names of drugs metabolized by CYP3A4 enzymes
Remember the code: “CT-SCAN”
Cyclosporine,
CCBs
Tacrolimus,
terfenadine Statins
Cisapride
Astemizole,
amiodarone
Navirs(Protease
Inhibitors)
To remember the names of drugs that require TDM(Therapeutic Drug Monitoring)
Remember the code: “A Drug Possessing Low Therapeutic Index”
*Tricyclic antidepressants
Aminoglycosides
Immunomodulators(Cyclo
sporine)
TCAs*LithiumPhenytoinDigoxin
To remember the drugs that cause SLE
Remember the code: “SHIP”
*Hydrochlorothiazide causes SLE(as published in American Journal of Case Reports, 2019)
Sulfonamides
Hydralazine,
Hydrochlorothiazide*
Isoniazid Procainamide
To remember the names of drugs that cause hemolysis in G,6-PD(Glucose-6-phosphate
dehydrogenase deficiency) patients
Remember the code : “PINS MCQ”
*Nitrofurantoin
Primaquine
Quinine
Chloroquine
Menadione
Sulfonamides
NTU*,
Nalidixic
acidIsoniazid
AUTONOMIC NERVOUS SYSTEM
To remember the names of drugs used in overactive bladder
Remember the name “SOFT BladDAR”
Solefenacin Darifenacin
Tolterodine,
trospium
Flavoxate,
fesoterodine
Oxybutynine
To remember the contraindications of non-selective beta-blockers
Remember the code : “ABCD”
*Congestive Heart Failure
** Diabetes Mellitus
Asthma DM**CHF*Block(AV)
To remember the names of cardioselective beta-blockers
Remember the code: “New Beta Blockers Acting Exclusively At Myo Cardium”
*Nebivolol  most cardioselective beta-blocker
Nebivolol* Betaxolol Bisoprolol Acebutolol Esmolol Atenolol Metoprolol Celiprolol
To remember the names of beta-blockers that can be safely used in patients prone to severe
bradycardia
Remember the code: “COntain Partial Agonistic Activity”
Celiprolol Oxprenolol
Pindolol,
penbutolol
Alprenolol Acebutolol
To remember the beta-blockers that possess anti-arrhythmic activity
Remember the code “Possess Membrane stabilizing or Local Anesthetic Property”
*Propranolol  shows maximum antiarrhythmic activity.
Propranolol* Metoprolol Labetalol Acebutolol Pindolol
To remember the names of lipid-insoluble beta-blockers
Remember the code: “Not Soluble ABC”
*Nadolol  longest-acting beta-blocker(Esmolol is shortest acting)
Nadolol* Celiprolol
Betaxolol,
bisoprolol
Atenolol,
acebutolol
Sotalol
AUTACOIDS
To remember the anti-cholinergic uses of H1-antihistaminics
Remember the code: “Possess Anti Cholinergic Properties”
Parkinsonism
Prophylaxis
of motion
sickness
Common
cold
Acute
muscular
dystonia
To remember the uses of Colchicine
Remember the code: “SLUM”
*Colchicine  indicated for prophylaxis of recurrent attacks of gouty arthritis.
Sarcoid
arthritis
Mediterranean
fever
Uric acid
elevation*
Liver cirrhosis
CARDIOVASCULAR SYSTEM
To remember the contraindications of digoxin
Remember the code: “Contraindicated IN Weak HEART”
* Wolff-Parkinson-White Syndrome
** Both hypothyroidism and hyperthyroidism.
Carditis
Thyroid
dysfunction**
Hypokalemia,
hypomagnesemia
Renal
failure
AV
block(partial)
Elderly
WPW
syndrome*
Increased
calcium
To remember the properties of ACE-Inhibitors
Remember the code: “CAPTOPRIL”
* Except captopril & lisinopril
** Especially when combined with diuretics
C: Cough P: Pregnancy(contraindicated!)
A: Angioedema R: Renal artery stenosis(contraindicated!)
P: Prodrugs* Increased K+ (contraindicated!)
T: Taste disturbances Lower the formation of Angiotensin-II
(Mechanism of action)
O: Orthostatic hypotension**
To remember the names of Class-III antiarrhythmics
Remember the code: “BInDAS”
Bretylium SotalolAmiodarone
Dofetilide,
dronedarone
Ibutilide
To remember the adverse effects of amiodarone
Remember the code: “The Periphery of My Lung Liver and Cornea is Photosensitive”
Thyroid
dysfunction
Peripheral
neuropathy
Myocardial
depression
Lung
fibrosis
Liver toxicity
(cirrhosis)
Corneal
microdeposits
Photosensitivity
To remember the special features of pravastatin(compared to other statins)
Remember the code: “5 MINIMUMs”
*Pravastatin  metabolized by non-microsomal enzymes  lesser risk of drug interactions!
** Food  increases absorption of all statins except pravastatin!
Minimum
drug
interactions*
Minimum
food
interactions**
Minimum
risk of
myopathy
Minimum
CNS
penetration
Minimize
(decrease)
fibrinogen level
To remember the drugs that cause gynecomastia
Remember the code: “DISCO”
Other drugs that cause gynecomastia include “Ketoconazole” & “Anti-testosterones”!
Digitalis INH Oestrogens
Cimetidi
ne
Spironola
ctone
ENDOCRINE SYSTEM
To remember the indications of somatostatin analogs
Remember the code: “SOMATOStatin”
Secretory
diarrhea
Overdose of
sulfonylureas
TSH-
secreting
adenoma
Acromegaly
Malignancy(Islet
cell tumors)
Oesophageal
varices
To remember the indications of bromocriptine
Remember the code “DOPAMINe”
Diabetes
Mellitus(Type
II)
Acromegaly
Milk secretion
inhibition(suppression of
lactation)
Parkinsonism
Oversecretion of
prolactin
To remember the risk factors for developing lactic acidosis with metformin therapy
Remember the code: “LAURELS”
Liver
disease
Alcoholics
Severe
hypoxemia
Unstable
CHF
Renal
dysfunction
Elderly
Lactic acidosis
history(or any form
of acidosis)
To remember the adverse effects & contraindications of steroids
Remember the code: “GLUCOCORTICOIDS”
G: Glaucoma(on topical use) T: Tuberculosis*
L: Limb muscle atrophy I: Impaired healing
U: Ulcer(Peptic Ulcer) C: CHF(Contraindicated!)
C: Cushing syndrome O: Oedema
O: Osteoporosis(contraindicated!) I: Infections(owing to immunosuppression)
C: Cataract(on systemic use) D: Diabetes mellitus
O: Osteonecrosis(avascular necrosis) S: Suppression of HPA-axis
R: Renal failure(contraindicated!)
*Corticosteroids are
contraindicated in
ileo-caecal TB!
To remember the protective effects of tamoxifen
Remember the code “BBB(TRIPLE B)”
Bone(reduces
bone resorption)
Blood(reduces LDL
& increases HDL)
Breast(prevents
breast carcinoma)
To remember the indications of Mifepristone
Remember the code: “MIFEPRIStone”
Meningioma
Induction of
abortion
Fibroid Endometriosis
Progesterone
receptor positive
breast cancer
Increased
steroids(Cushing
Syndrome)
To remember the non-contraceptive protective effects of oral contraceptives
Remember the code: “Other BENEFITS”
Other: Ovarian cyst F: Fibroids
B: Benign breast disease I: Iron-deficiency anemia
E: Ectopic pregnancy T: Tension(Pre-menstrual tension syndrome)
N: Neoplasia(ovarian, endometrial, colon
cancer)
S: Skeletal benefits(RA & Osteoporosis)
E: Endometriosis
CENTRAL NERVOUS SYSTEM
To remember the drugs that are contraindicated in porphyria
Remember the code: “SEVERE PORPHYriA”
*Also other barbiturates like thiopentone.
S: Sulfonamides P: Phenobarbitone*
E: Erythromycin OR: Oral contraceptives
V: Valproate acid P: Phenytoin
E: Ergot alkaloids HY: Hydralazine
R: Rifampicin A: Alcohol
E: Estrogens
To remember the names of short-acting benzodiazepines
Remember the code: “LOT*”
*Estazolam is also a short-acting benzodiazepine
Lorazepam TriazolamTemazepamOxazepam
To remember the adverse effects of phenytoin
Remember the code: “MILK OATH”
M: Megaloblastic anemia O: Osteomalacia
I: Inhibition of insulin
release(hyperglycemia)
A:Ataxia, arrhythmias
L: Lymphadenopathy T: Teratogenicity
K: Vitamin “K” deficiency H: Hirsutism, hypertrophy of gums.
To remember the adverse effects of valproate
Remember the code: “VALPROATE”
V: Vomiting O: Obesity
A: Alopecia A: Agranulocytosis
L: Liver damage T: Tremors
P: PCOD, Pancreatitis E: Epigastric pain
R: Rash
To remember the uses of anti-psychotics
Remember the code: “ANTI PSY-CHO-TIC”
Anti-emetic Psychosis
Tic disorders (Gilles de
la Tourette syndrome)
Chorea
To remember the indications of antidepressants
Remember the code: “DEPRESSION”
D: Depression S: Smoking cessation(bupropion)
E: Enuresis(imipramine) S: Stress disorder(Post-traumatic)
P: Phobia I: Impulse disorder(Kleptomania)
R: Recurrent panic attacks O: Obsessive compulsive disorder
E: Eating disorder(bulimia) N: Neuropathic pain
To remember the drugs that cause disulfiram-like reaction
Remember the code: “Cyclic-GMP”
Cefoperazone CefomandoleChlorpropamideCefotetan
Griseofulvin
Metronidazole,
moxalactam
Procarbazine
To remember the names of drugs that reduce alcohol craving
Remember the code: “None Of The Above”
Naltrexone Ondansetron Topiramate Acamprosate
ANAESTHETICS
To remember the names of local anesthetics that cause methemoglobinemia
Remember the code: “BPL”
*Prilocaine has maximum risk of causing methemoglobinemia
Benzocaine Prilocaine* Lignocaine
To remember the properties of halothane
Remember the code: “HALOTHANE CCC”
H: Hyperthermia(malignant
hyperthermia)
H: Heart(cardio depressant activity 
reduces C.O)
A: Arrhythmias(sensitizes heart to
adrenaline
A: Asthma(bronchodilator)
L: Liver toxic NE: Non-Explosive
O: Orthostatic hypotension C: Chills(Post- anesthetic shivering)
T: Tocolytic C: Children(Safe in children)
To remember the names of inhalational anesthetics that can cause seizures
Remember the code: “SEIzure”
*Enflurane  maximum potentiality to precipitate seizure!
Sevoflurane IsofluraneEnflurane*
To remember the properties of ketamine
Remember the code: “KETAMINE”
*Hallucinations, illusions, vivid dreams, etc. observed while recovery from anesthesia
** Responsible for dissociative anesthesia
*** Maximum analgesic property among all anesthetics!
K: Kids(i.v anesthetic of choice in
children)
M: Meals(can be given in full stomach)
E: Emergence reaction* I: Increases all pressures (ICT, IOP, BP)
T: Thalamocortical junction(site of
action)**
N: NMDA antagonist
A: Analgesic*** E: Excellent for asthmatics
To remember the drugs useful for day care surgery
Remember the code “Dr. Manmohan Singh Is A Prime Minister”
*Benzodiazepine
Dr. : Desflurane A: Alfentanil
Manmohan: Midazolam(BZD)* Prime: Propofol
Singh: Sevoflurane Minister: Mivacurium(Muscle
relaxant)
Is: Isoflurane
HEMATOLOGICAL SYSTEM
To remember the causes of megaloblastic anemia
Remember the code : “Prime BATSMAN”
*Also folic acid deficiency!
Prime: Primidone, phenytoin S: Sulfasalazine
B: B-12 vitamin deficiency* M: Metformin
A: Alcohol A: Antifolates(methotrexate,
pyrimethamine, proguanil)
T: Trimethoprim N: Nitrous oxide
ANTIBIOTICS
To remember the names of antibiotics that can be safely used in renal disease
Remember the code: “DANCER*”
*Lincosamides(clindamycin) are also safe in renal disease!
D: Doxycyline C: Cefoperazone, ceftriaxone
A: Ampicillin E: Erythromycin
N: Nafcillin R: Rifampicin
To remember the names of acid-resistant penicillins
Remember the code: “VODKA”
Penicillin V Oxacillin Dicloxacillin Cloxacillin
Amoxicillin,
ampicillin
To remember the names of anti-pseudomonal penicillins
Remember the code: “CT-MAP”
Carbenicillin Ticarcillin Mezlocillin Azlocillin Piperacillin
To remember the principal indications of Penicillin ‘G’
Remember the code: “LASTMAn”
*Non-penicillinase producing
**Ciprofloxacin can also be considered as 1st line choice.
Leptospira Actinomyces
Streptococcus,
Staphylococcus*
Treponema,
Tetanus
Meningococcus Anthrax**
To remember the indications of tetracyclines
Remember the code: “RBC In PLASMA”
R: Rickettsia, relapsing fever L: LGV(Lymphogranuloma venereum)
B: Brucellosis A: Atypical pneumonia
C: Cholera, chlamydia S: SIADH
In: Inguinale(granuloma) M: Malaria
P: Plague, peptic ulcer, pleurodesmosis A: Amoebiasis.
To remember the adverse effects of tetracyclines
Remember the code: “KAPIL DEV”
*All tetracyclines are contraindicated in kidney dysfunction except minocycline.
K: Kidney failure* L: Liver toxicity(hepatic necrosis)
A: Antianabolic effect D: Dentition & bone defects
P: Photosensitivity(maximum with
demeclocycline)
E: Expired drugs  can cause Fanconi’s
syndrome
I: Insipidus(diabetes insipidus, maximum
with demeclocycline)
V: Vestibular dysfunction(maximum with
minocycline)
To remember the principal indications of macrolides
Remember the code : “CLAW”
*Azithromycin single dose is given.
C: Chancroid* by hemophilus ducreyi,
Corynebacterium(diphtheria) &
campylobacter
A: Atypical pneumonia
L: Legionella infections W: Whooping cough(by Bordetella
pertussis)
To remember the common indications of azithromycin & clarithromycin
Remember the code: “CHAT”
C: Chlamydia A: Avium complex(MAC)
H: H.influenzae T: Toxoplasma.
To remember the adverse effects of macrolides
Remember the code: “MACRO”
*Motilin receptor agonism  leads to diarrhea
Motilin receptor
agonism*
Allergy
Reversible
ototoxicity
Cholestasis
To remember the indications of clindamycin
Remember the code: “PACT”
P: Pneumocystis jiroveci, plasmodium
parasite
C: Cocci(Gram +ve)
A: Anaerobes T: Toxoplasma gondii
To remember the chief indications of co-trimoxazole
Remember the code: “Punjab National Bank”
Pneumocystis
Burkholderia
cepacia
Nocardia
To remember the adverse effects of sulfonamides
Remember the code: “ABC RASH”
*Most common adverse effect
**In G-6-PD(Glucose-6-phosphate dehydrogenase) deficient patients.
A: Aplastic anemia R: Rash*
B: Bilirubin displacement(kernicterus) AS: Acetylation leads to SLE
C: Crystalluria H: Hemolysis**
To remember the antibiotics that are effective against anaerobes
Remember the code: “Cyto Megalo Virus(CMV)”
N.B: Trovafloxacin was also active against anaerobes, but the drug is banned now.
C: Clindamycin, cefmetazole, cefotetan, cefoxitin, chloramphenicol
M: Moxifloxacin, metronidazole
V: Vancomycin
To remember the names of substances that cause “ototoxicity”
Remember the code: “DEAFNESS Causing Vital Medicines”
D: Diclofenac S: Salicylates
E: Ethacrynic acid S: Smoking
A: Aminoglycosides Causing: Cisplatin
F: Furosemide Vital: Vancomycin, vinblastine
N: Nitrogen mustards Medicines: Malarial drugs(quinine)
E: Erythromycin
ANTI-VIRALS
To remember the anti-virals that are effective against both HBV & HIV viruses
Remember the code: “LET”
L: Lamivudine
E: Emtricitabine
T: Tenofovir
ANTI-TUBERCULARS
To remember the names of aminoglycoside antitubercular drugs
Remember the code: “SACK”
Streptomycin KanamycinCapreomycinAmikacin
To remember the names of Group 1 antitubercular drugs*
Remember the code: “RIPE”
*Based on RNTCP guideline-associated classification.
Rifampin EthambutolPyrazinamideIsoniazid
ANTI-MALARIALS
To remember the names of fast-acting erythrocytic schizonticides
Remember the code: “Mango ACHAR”**
**Also lumefantrine, piperaquine.
Mango: Mefloquine H: Halofantrine
A: Atovaquone, amodiaquine A: Artemisinins
C: Chloroquine R: Res-Q(Quinine)
To remember the uses of chloroquine
Remember the code: “REDMI-LPG”
R: Rheumatoid arthritis I: Infectious mononucleosis
E: Extraintestinal amoebiasis L: Lepra reaction
D: Discoid lupus erythematosus P: Photogenic reactions
M: Malaria G: Giardiasis
DRUGS FOR AMOEBIASIS
To remember the preferential indications of metronidazole
Remember the code: “GUPTA”
G: Giardiasis, gardernella
vaginalis(bacterial vaginosis)
T: Trichomoniasis
U: Ulcer(H.pylori-associated peptic ulcer
disease)
A: Amoebiasis, anaerobic
bacteria(bacteroides, clostridium)
P: Pseudomembranous colitis, induced by
Clostridium difficile
ANTI-FUNGALS
To remember the adverse effects of Amphotericin-B
Remember the code: “AMPHOTERICIN-B”
A: Anemia R: Respiratory stridor
M: Muscle spasms I: Increased temperature(fever)
P: Phlebitis C: Chills
H: Headache, hypotension, hypokalemia I: Immediate
hypersensitivity(anaphylaxis)
O: Ototoxicity N: Nephrotoxicity
T: Thrombocytopenia
E: Emesis, encephalopathy B: Bronchospasm
ANTI-CANCERS
To remember the uses of methotrexate
Remember the code: “Inhibit CANCER”
Inhibit: Immunosuppressant C: Choriocarcinoma
C: Crohn’s disease E: Ectopic pregnancy
A: Abortion R: Rheumatoid arthritis(RA)
N: Non-Hodgkin’s lymphoma(NHL)
To remember the uses of rituximab
Remember the code: “ReLIANCe”
Re: Rheumatoid arthritis A: Autoimmune hemolytic anemia
L: Lupus(SLE) N: Non-Hodgkin Lymphoma
I: ITP(Idiopathic thrombocytopenic
purpura)
Ce: CLL
To remember the tyrosine kinase inhibitors used for CML**
Remember the code: “BIND Proteins”
** Chronic myelogenous leukemia.
B: Bosutinib D: Dasatinib
I: Imatinib Proteins: Ponatinib
N: Nilotinib
To remember the names of tyrosine kinase inhibitors used for NSCLC**
Remember the code: “Operate After ECG”
**Non-small cell lung cancer
Operate: Osimertinib C: Crizotinib, ceritinib
After: Afatinib, alectinib G: Geftinib
E: Erlotinib
To remember the tyrosine kinase inhibitors indicated in GIST**
Remember the code: “SIR”!
**Gastro-intestinal stromal tumor
Sunitinib RegorafenibImatinib
To remember the tyrosine kinase inhibitors used for RCC**
Remember the code : “PASS”
**Renal cell carcinoma
P: Pazopanib S: Sorafenib
A: Axitinib S: Sunitinib
To remember the tyrosine kinase inhibitors indicated for malignant melanoma
Remember the code: “Cause DVT”
Cause: Cobemetinib V: Vemurafenib
D: Dabrafenib T: Trameltinib
THANK YOU!!!

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Drug mnemonics; by RxVichuZ! ;)

  • 1. PRESENTED BY: (DR.) VISHNU.R.NAIR, PHARM.D INTERN(AMRI HOSPITAL ACADEMIC TRAINEE), NATIONAL COLLEGE OF PHARMACY, KOZHIKODE, KERALA.
  • 2.  Pharmacology  one of the most difficult subjects in medical science!  Along with newer drugs that get approved each year  remembering the older ones  poses a significant impediment in the path of smooth memory!  Use of easy-to-remember mnemonics  helps in the following: - Easy interpretation - Easy memorizing - Contributes to smart work!  Hence this powerpoint  aims at presenting some clinically relevant drug mnemonics, that may be worthwhile for some! HAPPY READING!!
  • 4. To remember the names of drugs that undergo first-pass metabolism Remember the code: “Nitrates Have Large Pre Systemic Metabolism” Nitrates Morphine Salbutamol Propranolol Lignocaine Hydrocortiso ne
  • 5. To remember the relevance of protein binding of drug Remember the code “DDDD(4D)” PPB: Plasma protein binding. Duration of action: Drugs with high PPB  Long-acting! Dialysis: Drugs with high PPB  Can’t be removed by dialysis! Displacement: A high PPB drug  can displace another high PPB drug! Distribution: Drugs with high PPB  stay in plasma  low distribution!
  • 6. To remember the names of drugs, which cannot be eliminated by dialysis Remember the code “AVOID Dialysis” Amphetamines Digitalis Imipramine Diazepam Organophosph ates, opioids Verapamil
  • 7. To remember the names of prodrugs Remember the code: “All Prefer Doing MD In Clinical Subjects” *Except captopril & lisinopril ACE- inhibitors* Sulfasalazine Cyclophosphamide, carbimazole, clopidogrel Irinotecan, INH Dopamine precursor(L- dopa) Mercaptopurine , Methyldopa, Minoxidil Dipivefrine Prednisone, Proguanil, PPIs
  • 8. To remember the names of drugs/substances that are enzyme inducers Remember the code: “GPRS Cell Phone” *Carbamazepine Griseofulvin CBZ* Phenobarbitone Smoking(Nic otine)Rifampicin Phenytoin
  • 9. To remember the names of drugs that cause enzyme inhibition Remember the code: “Vitamin K Cannot Cause Enzyme Inhibition” *Isoniazid Valproate Ketoconazole INH* ErythromycinCiprofloxacin Cimetidine
  • 10. To remember the names of drugs metabolized by CYP3A4 enzymes Remember the code: “CT-SCAN” Cyclosporine, CCBs Tacrolimus, terfenadine Statins Cisapride Astemizole, amiodarone Navirs(Protease Inhibitors)
  • 11. To remember the names of drugs that require TDM(Therapeutic Drug Monitoring) Remember the code: “A Drug Possessing Low Therapeutic Index” *Tricyclic antidepressants Aminoglycosides Immunomodulators(Cyclo sporine) TCAs*LithiumPhenytoinDigoxin
  • 12. To remember the drugs that cause SLE Remember the code: “SHIP” *Hydrochlorothiazide causes SLE(as published in American Journal of Case Reports, 2019) Sulfonamides Hydralazine, Hydrochlorothiazide* Isoniazid Procainamide
  • 13.
  • 14. To remember the names of drugs that cause hemolysis in G,6-PD(Glucose-6-phosphate dehydrogenase deficiency) patients Remember the code : “PINS MCQ” *Nitrofurantoin Primaquine Quinine Chloroquine Menadione Sulfonamides NTU*, Nalidixic acidIsoniazid
  • 16. To remember the names of drugs used in overactive bladder Remember the name “SOFT BladDAR” Solefenacin Darifenacin Tolterodine, trospium Flavoxate, fesoterodine Oxybutynine
  • 17. To remember the contraindications of non-selective beta-blockers Remember the code : “ABCD” *Congestive Heart Failure ** Diabetes Mellitus Asthma DM**CHF*Block(AV)
  • 18. To remember the names of cardioselective beta-blockers Remember the code: “New Beta Blockers Acting Exclusively At Myo Cardium” *Nebivolol  most cardioselective beta-blocker Nebivolol* Betaxolol Bisoprolol Acebutolol Esmolol Atenolol Metoprolol Celiprolol
  • 19. To remember the names of beta-blockers that can be safely used in patients prone to severe bradycardia Remember the code: “COntain Partial Agonistic Activity” Celiprolol Oxprenolol Pindolol, penbutolol Alprenolol Acebutolol
  • 20. To remember the beta-blockers that possess anti-arrhythmic activity Remember the code “Possess Membrane stabilizing or Local Anesthetic Property” *Propranolol  shows maximum antiarrhythmic activity. Propranolol* Metoprolol Labetalol Acebutolol Pindolol
  • 21. To remember the names of lipid-insoluble beta-blockers Remember the code: “Not Soluble ABC” *Nadolol  longest-acting beta-blocker(Esmolol is shortest acting) Nadolol* Celiprolol Betaxolol, bisoprolol Atenolol, acebutolol Sotalol
  • 23. To remember the anti-cholinergic uses of H1-antihistaminics Remember the code: “Possess Anti Cholinergic Properties” Parkinsonism Prophylaxis of motion sickness Common cold Acute muscular dystonia
  • 24. To remember the uses of Colchicine Remember the code: “SLUM” *Colchicine  indicated for prophylaxis of recurrent attacks of gouty arthritis. Sarcoid arthritis Mediterranean fever Uric acid elevation* Liver cirrhosis
  • 26. To remember the contraindications of digoxin Remember the code: “Contraindicated IN Weak HEART” * Wolff-Parkinson-White Syndrome ** Both hypothyroidism and hyperthyroidism. Carditis Thyroid dysfunction** Hypokalemia, hypomagnesemia Renal failure AV block(partial) Elderly WPW syndrome* Increased calcium
  • 27. To remember the properties of ACE-Inhibitors Remember the code: “CAPTOPRIL” * Except captopril & lisinopril ** Especially when combined with diuretics C: Cough P: Pregnancy(contraindicated!) A: Angioedema R: Renal artery stenosis(contraindicated!) P: Prodrugs* Increased K+ (contraindicated!) T: Taste disturbances Lower the formation of Angiotensin-II (Mechanism of action) O: Orthostatic hypotension**
  • 28. To remember the names of Class-III antiarrhythmics Remember the code: “BInDAS” Bretylium SotalolAmiodarone Dofetilide, dronedarone Ibutilide
  • 29. To remember the adverse effects of amiodarone Remember the code: “The Periphery of My Lung Liver and Cornea is Photosensitive” Thyroid dysfunction Peripheral neuropathy Myocardial depression Lung fibrosis Liver toxicity (cirrhosis) Corneal microdeposits Photosensitivity
  • 30. To remember the special features of pravastatin(compared to other statins) Remember the code: “5 MINIMUMs” *Pravastatin  metabolized by non-microsomal enzymes  lesser risk of drug interactions! ** Food  increases absorption of all statins except pravastatin! Minimum drug interactions* Minimum food interactions** Minimum risk of myopathy Minimum CNS penetration Minimize (decrease) fibrinogen level
  • 31. To remember the drugs that cause gynecomastia Remember the code: “DISCO” Other drugs that cause gynecomastia include “Ketoconazole” & “Anti-testosterones”! Digitalis INH Oestrogens Cimetidi ne Spironola ctone
  • 33. To remember the indications of somatostatin analogs Remember the code: “SOMATOStatin” Secretory diarrhea Overdose of sulfonylureas TSH- secreting adenoma Acromegaly Malignancy(Islet cell tumors) Oesophageal varices
  • 34. To remember the indications of bromocriptine Remember the code “DOPAMINe” Diabetes Mellitus(Type II) Acromegaly Milk secretion inhibition(suppression of lactation) Parkinsonism Oversecretion of prolactin
  • 35. To remember the risk factors for developing lactic acidosis with metformin therapy Remember the code: “LAURELS” Liver disease Alcoholics Severe hypoxemia Unstable CHF Renal dysfunction Elderly Lactic acidosis history(or any form of acidosis)
  • 36. To remember the adverse effects & contraindications of steroids Remember the code: “GLUCOCORTICOIDS” G: Glaucoma(on topical use) T: Tuberculosis* L: Limb muscle atrophy I: Impaired healing U: Ulcer(Peptic Ulcer) C: CHF(Contraindicated!) C: Cushing syndrome O: Oedema O: Osteoporosis(contraindicated!) I: Infections(owing to immunosuppression) C: Cataract(on systemic use) D: Diabetes mellitus O: Osteonecrosis(avascular necrosis) S: Suppression of HPA-axis R: Renal failure(contraindicated!) *Corticosteroids are contraindicated in ileo-caecal TB!
  • 37. To remember the protective effects of tamoxifen Remember the code “BBB(TRIPLE B)” Bone(reduces bone resorption) Blood(reduces LDL & increases HDL) Breast(prevents breast carcinoma)
  • 38. To remember the indications of Mifepristone Remember the code: “MIFEPRIStone” Meningioma Induction of abortion Fibroid Endometriosis Progesterone receptor positive breast cancer Increased steroids(Cushing Syndrome)
  • 39. To remember the non-contraceptive protective effects of oral contraceptives Remember the code: “Other BENEFITS” Other: Ovarian cyst F: Fibroids B: Benign breast disease I: Iron-deficiency anemia E: Ectopic pregnancy T: Tension(Pre-menstrual tension syndrome) N: Neoplasia(ovarian, endometrial, colon cancer) S: Skeletal benefits(RA & Osteoporosis) E: Endometriosis
  • 41. To remember the drugs that are contraindicated in porphyria Remember the code: “SEVERE PORPHYriA” *Also other barbiturates like thiopentone. S: Sulfonamides P: Phenobarbitone* E: Erythromycin OR: Oral contraceptives V: Valproate acid P: Phenytoin E: Ergot alkaloids HY: Hydralazine R: Rifampicin A: Alcohol E: Estrogens
  • 42. To remember the names of short-acting benzodiazepines Remember the code: “LOT*” *Estazolam is also a short-acting benzodiazepine Lorazepam TriazolamTemazepamOxazepam
  • 43. To remember the adverse effects of phenytoin Remember the code: “MILK OATH” M: Megaloblastic anemia O: Osteomalacia I: Inhibition of insulin release(hyperglycemia) A:Ataxia, arrhythmias L: Lymphadenopathy T: Teratogenicity K: Vitamin “K” deficiency H: Hirsutism, hypertrophy of gums.
  • 44. To remember the adverse effects of valproate Remember the code: “VALPROATE” V: Vomiting O: Obesity A: Alopecia A: Agranulocytosis L: Liver damage T: Tremors P: PCOD, Pancreatitis E: Epigastric pain R: Rash
  • 45. To remember the uses of anti-psychotics Remember the code: “ANTI PSY-CHO-TIC” Anti-emetic Psychosis Tic disorders (Gilles de la Tourette syndrome) Chorea
  • 46. To remember the indications of antidepressants Remember the code: “DEPRESSION” D: Depression S: Smoking cessation(bupropion) E: Enuresis(imipramine) S: Stress disorder(Post-traumatic) P: Phobia I: Impulse disorder(Kleptomania) R: Recurrent panic attacks O: Obsessive compulsive disorder E: Eating disorder(bulimia) N: Neuropathic pain
  • 47. To remember the drugs that cause disulfiram-like reaction Remember the code: “Cyclic-GMP” Cefoperazone CefomandoleChlorpropamideCefotetan Griseofulvin Metronidazole, moxalactam Procarbazine
  • 48. To remember the names of drugs that reduce alcohol craving Remember the code: “None Of The Above” Naltrexone Ondansetron Topiramate Acamprosate
  • 50. To remember the names of local anesthetics that cause methemoglobinemia Remember the code: “BPL” *Prilocaine has maximum risk of causing methemoglobinemia Benzocaine Prilocaine* Lignocaine
  • 51. To remember the properties of halothane Remember the code: “HALOTHANE CCC” H: Hyperthermia(malignant hyperthermia) H: Heart(cardio depressant activity  reduces C.O) A: Arrhythmias(sensitizes heart to adrenaline A: Asthma(bronchodilator) L: Liver toxic NE: Non-Explosive O: Orthostatic hypotension C: Chills(Post- anesthetic shivering) T: Tocolytic C: Children(Safe in children)
  • 52. To remember the names of inhalational anesthetics that can cause seizures Remember the code: “SEIzure” *Enflurane  maximum potentiality to precipitate seizure! Sevoflurane IsofluraneEnflurane*
  • 53. To remember the properties of ketamine Remember the code: “KETAMINE” *Hallucinations, illusions, vivid dreams, etc. observed while recovery from anesthesia ** Responsible for dissociative anesthesia *** Maximum analgesic property among all anesthetics! K: Kids(i.v anesthetic of choice in children) M: Meals(can be given in full stomach) E: Emergence reaction* I: Increases all pressures (ICT, IOP, BP) T: Thalamocortical junction(site of action)** N: NMDA antagonist A: Analgesic*** E: Excellent for asthmatics
  • 54. To remember the drugs useful for day care surgery Remember the code “Dr. Manmohan Singh Is A Prime Minister” *Benzodiazepine Dr. : Desflurane A: Alfentanil Manmohan: Midazolam(BZD)* Prime: Propofol Singh: Sevoflurane Minister: Mivacurium(Muscle relaxant) Is: Isoflurane
  • 56. To remember the causes of megaloblastic anemia Remember the code : “Prime BATSMAN” *Also folic acid deficiency! Prime: Primidone, phenytoin S: Sulfasalazine B: B-12 vitamin deficiency* M: Metformin A: Alcohol A: Antifolates(methotrexate, pyrimethamine, proguanil) T: Trimethoprim N: Nitrous oxide
  • 58. To remember the names of antibiotics that can be safely used in renal disease Remember the code: “DANCER*” *Lincosamides(clindamycin) are also safe in renal disease! D: Doxycyline C: Cefoperazone, ceftriaxone A: Ampicillin E: Erythromycin N: Nafcillin R: Rifampicin
  • 59. To remember the names of acid-resistant penicillins Remember the code: “VODKA” Penicillin V Oxacillin Dicloxacillin Cloxacillin Amoxicillin, ampicillin
  • 60. To remember the names of anti-pseudomonal penicillins Remember the code: “CT-MAP” Carbenicillin Ticarcillin Mezlocillin Azlocillin Piperacillin
  • 61. To remember the principal indications of Penicillin ‘G’ Remember the code: “LASTMAn” *Non-penicillinase producing **Ciprofloxacin can also be considered as 1st line choice. Leptospira Actinomyces Streptococcus, Staphylococcus* Treponema, Tetanus Meningococcus Anthrax**
  • 62. To remember the indications of tetracyclines Remember the code: “RBC In PLASMA” R: Rickettsia, relapsing fever L: LGV(Lymphogranuloma venereum) B: Brucellosis A: Atypical pneumonia C: Cholera, chlamydia S: SIADH In: Inguinale(granuloma) M: Malaria P: Plague, peptic ulcer, pleurodesmosis A: Amoebiasis.
  • 63. To remember the adverse effects of tetracyclines Remember the code: “KAPIL DEV” *All tetracyclines are contraindicated in kidney dysfunction except minocycline. K: Kidney failure* L: Liver toxicity(hepatic necrosis) A: Antianabolic effect D: Dentition & bone defects P: Photosensitivity(maximum with demeclocycline) E: Expired drugs  can cause Fanconi’s syndrome I: Insipidus(diabetes insipidus, maximum with demeclocycline) V: Vestibular dysfunction(maximum with minocycline)
  • 64. To remember the principal indications of macrolides Remember the code : “CLAW” *Azithromycin single dose is given. C: Chancroid* by hemophilus ducreyi, Corynebacterium(diphtheria) & campylobacter A: Atypical pneumonia L: Legionella infections W: Whooping cough(by Bordetella pertussis)
  • 65. To remember the common indications of azithromycin & clarithromycin Remember the code: “CHAT” C: Chlamydia A: Avium complex(MAC) H: H.influenzae T: Toxoplasma.
  • 66. To remember the adverse effects of macrolides Remember the code: “MACRO” *Motilin receptor agonism  leads to diarrhea Motilin receptor agonism* Allergy Reversible ototoxicity Cholestasis
  • 67. To remember the indications of clindamycin Remember the code: “PACT” P: Pneumocystis jiroveci, plasmodium parasite C: Cocci(Gram +ve) A: Anaerobes T: Toxoplasma gondii
  • 68. To remember the chief indications of co-trimoxazole Remember the code: “Punjab National Bank” Pneumocystis Burkholderia cepacia Nocardia
  • 69. To remember the adverse effects of sulfonamides Remember the code: “ABC RASH” *Most common adverse effect **In G-6-PD(Glucose-6-phosphate dehydrogenase) deficient patients. A: Aplastic anemia R: Rash* B: Bilirubin displacement(kernicterus) AS: Acetylation leads to SLE C: Crystalluria H: Hemolysis**
  • 70. To remember the antibiotics that are effective against anaerobes Remember the code: “Cyto Megalo Virus(CMV)” N.B: Trovafloxacin was also active against anaerobes, but the drug is banned now. C: Clindamycin, cefmetazole, cefotetan, cefoxitin, chloramphenicol M: Moxifloxacin, metronidazole V: Vancomycin
  • 71. To remember the names of substances that cause “ototoxicity” Remember the code: “DEAFNESS Causing Vital Medicines” D: Diclofenac S: Salicylates E: Ethacrynic acid S: Smoking A: Aminoglycosides Causing: Cisplatin F: Furosemide Vital: Vancomycin, vinblastine N: Nitrogen mustards Medicines: Malarial drugs(quinine) E: Erythromycin
  • 73. To remember the anti-virals that are effective against both HBV & HIV viruses Remember the code: “LET” L: Lamivudine E: Emtricitabine T: Tenofovir
  • 75. To remember the names of aminoglycoside antitubercular drugs Remember the code: “SACK” Streptomycin KanamycinCapreomycinAmikacin
  • 76. To remember the names of Group 1 antitubercular drugs* Remember the code: “RIPE” *Based on RNTCP guideline-associated classification. Rifampin EthambutolPyrazinamideIsoniazid
  • 78. To remember the names of fast-acting erythrocytic schizonticides Remember the code: “Mango ACHAR”** **Also lumefantrine, piperaquine. Mango: Mefloquine H: Halofantrine A: Atovaquone, amodiaquine A: Artemisinins C: Chloroquine R: Res-Q(Quinine)
  • 79. To remember the uses of chloroquine Remember the code: “REDMI-LPG” R: Rheumatoid arthritis I: Infectious mononucleosis E: Extraintestinal amoebiasis L: Lepra reaction D: Discoid lupus erythematosus P: Photogenic reactions M: Malaria G: Giardiasis
  • 81. To remember the preferential indications of metronidazole Remember the code: “GUPTA” G: Giardiasis, gardernella vaginalis(bacterial vaginosis) T: Trichomoniasis U: Ulcer(H.pylori-associated peptic ulcer disease) A: Amoebiasis, anaerobic bacteria(bacteroides, clostridium) P: Pseudomembranous colitis, induced by Clostridium difficile
  • 83. To remember the adverse effects of Amphotericin-B Remember the code: “AMPHOTERICIN-B” A: Anemia R: Respiratory stridor M: Muscle spasms I: Increased temperature(fever) P: Phlebitis C: Chills H: Headache, hypotension, hypokalemia I: Immediate hypersensitivity(anaphylaxis) O: Ototoxicity N: Nephrotoxicity T: Thrombocytopenia E: Emesis, encephalopathy B: Bronchospasm
  • 85. To remember the uses of methotrexate Remember the code: “Inhibit CANCER” Inhibit: Immunosuppressant C: Choriocarcinoma C: Crohn’s disease E: Ectopic pregnancy A: Abortion R: Rheumatoid arthritis(RA) N: Non-Hodgkin’s lymphoma(NHL)
  • 86. To remember the uses of rituximab Remember the code: “ReLIANCe” Re: Rheumatoid arthritis A: Autoimmune hemolytic anemia L: Lupus(SLE) N: Non-Hodgkin Lymphoma I: ITP(Idiopathic thrombocytopenic purpura) Ce: CLL
  • 87. To remember the tyrosine kinase inhibitors used for CML** Remember the code: “BIND Proteins” ** Chronic myelogenous leukemia. B: Bosutinib D: Dasatinib I: Imatinib Proteins: Ponatinib N: Nilotinib
  • 88. To remember the names of tyrosine kinase inhibitors used for NSCLC** Remember the code: “Operate After ECG” **Non-small cell lung cancer Operate: Osimertinib C: Crizotinib, ceritinib After: Afatinib, alectinib G: Geftinib E: Erlotinib
  • 89. To remember the tyrosine kinase inhibitors indicated in GIST** Remember the code: “SIR”! **Gastro-intestinal stromal tumor Sunitinib RegorafenibImatinib
  • 90. To remember the tyrosine kinase inhibitors used for RCC** Remember the code : “PASS” **Renal cell carcinoma P: Pazopanib S: Sorafenib A: Axitinib S: Sunitinib
  • 91. To remember the tyrosine kinase inhibitors indicated for malignant melanoma Remember the code: “Cause DVT” Cause: Cobemetinib V: Vemurafenib D: Dabrafenib T: Trameltinib