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Presented by:Salam Elayeh
DVM; urmia university
2013
Fowl cholera is a highly contagious disease of domestic and
wild birds.Sudden death because of diarrhea→just like man
chol...
Pasteurella
multocida
P.gallicida
P.septicaP.multocida
Gram-negative, non-spore-forming, rod shaped
bi polar Bacteria
•5 serogroup
•A,B,D,E,F
Capsular
antigens
•16 serogroup
•1−16
Somatic
antigens
Attack many kinds of birds as like as:
Fowl,Turkey,Duck,Geese,wild
bird,water fowl. Turkey are more
sensitive than each ot...
Morbidity:10-80
Mortality:turkey →68
duck→50
poultry→15-50
Age: older than 16 w in layer
4-5 w in broiler
Season:autumn an...
Enterance:
1-URT mucosal membrane
2-conjunctiva
3-cutaneous wounds
Incubation period:4-9 days
1. start of acute septicemia with coagulopaties
2.production of endotoxin →oedema ,
haemorrhagia ,shock,sudden deaths
3.ba...
1.Direct contact or aerosol (excretes)
source → latently infected or chronic sick birds
location of infection → URT and na...
Chronic course
 Failure of growth and developement of body
 Drop in egg production
 Swelling of wattles, sinuses
 Swel...
In the chronic form of fowl cholera, suppurative lesions may be found in
a variety of locations. In this broiler breeder, ...
Acute form
 Petechia to ecchymosis on serosis and mucous membrane
 exsudative pneumonia
 Sub acute form
 Petechia to e...
Fowl cholera. Small areas of necrosis in the liver (corn meal liver)
hyperemic
Hemorrhage in heart muscle Haemorrhages in intestine (different extent)
Wattle form, artritis, osteomyelitis
Exsudative serositis
sinusitis
Purulent exudate may be found within the facial swellings
The foot has been incised to show a caseous exudate .
1.history, sings and lesions
2.bacteriology
3.indentification by using biochemical test
4.now is available PCR test
5.bipo...
Bluedomethylene,lichman,gimsa staining→bipolar bacteria
Heart and livers blood
Culture in : dextrose starch agar +5%serum
...
1.Infectious coryza
2.Fowl typhoid
3.Fowl plague(avian flu)
4.Duck plaque(duck herpes virus 1)
5.Otherpaseurellas(p.haemol...
1-Wild birds
2-Rodents
3-cat.dog,pigs,…
4-Vaccination
1 -live attenuated
2-in activated : razi institute A: 1
Best→(-):1,3,4
Age : 8-10 and 18-20 w
In poultry →IM
In turkey →DW
1-Sulfa drugs
2-Semisynthetic penicillins
3-Tertracyclines
4-Erythromycin
Thanks
Fowl cholera. clinical signs,diagnosis, treatment, vaccination and prevention.by salam elayh
Fowl cholera. clinical signs,diagnosis, treatment, vaccination and prevention.by salam elayh
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Fowl cholera. clinical signs,diagnosis, treatment, vaccination and prevention.by salam elayh

Fowl cholera. clinical signs,diagnosis, treatment, vaccination and prevention.by salam elayh.DVM.Urmia.University

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Fowl cholera. clinical signs,diagnosis, treatment, vaccination and prevention.by salam elayh

  1. 1. Presented by:Salam Elayeh DVM; urmia university 2013
  2. 2. Fowl cholera is a highly contagious disease of domestic and wild birds.Sudden death because of diarrhea→just like man cholera. Importance:1-economicly.2-historical (pasteur) 3- biological:wild birds
  3. 3. Pasteurella multocida P.gallicida P.septicaP.multocida
  4. 4. Gram-negative, non-spore-forming, rod shaped bi polar Bacteria
  5. 5. •5 serogroup •A,B,D,E,F Capsular antigens •16 serogroup •1−16 Somatic antigens
  6. 6. Attack many kinds of birds as like as: Fowl,Turkey,Duck,Geese,wild bird,water fowl. Turkey are more sensitive than each others.Some domestic mammals are olso susceptible
  7. 7. Morbidity:10-80 Mortality:turkey →68 duck→50 poultry→15-50 Age: older than 16 w in layer 4-5 w in broiler Season:autumn and winter
  8. 8. Enterance: 1-URT mucosal membrane 2-conjunctiva 3-cutaneous wounds Incubation period:4-9 days
  9. 9. 1. start of acute septicemia with coagulopaties 2.production of endotoxin →oedema , haemorrhagia ,shock,sudden deaths 3.bacteraemia→spreading to lung 4.influencing factors →1- crowding, 2-clima,3- concurrent infection 4-nutrition,5- biosecurity, 6-injury and stress
  10. 10. 1.Direct contact or aerosol (excretes) source → latently infected or chronic sick birds location of infection → URT and nasal cavity 2.Indirectly → personnel and equipment, vectors →pigs, cattle, cats, wild birds, rodents, insects Incubation period→4-9 days
  11. 11. Chronic course  Failure of growth and developement of body  Drop in egg production  Swelling of wattles, sinuses  Swelling of joints, foot pad, sternal bursa  Torticolis  Dermal necrosis in turkey  Granulomatous dermatitis in pigeons and birds of prey
  12. 12. In the chronic form of fowl cholera, suppurative lesions may be found in a variety of locations. In this broiler breeder, severe swelling of the infraorbital sinuses is found on external examination .
  13. 13. Acute form  Petechia to ecchymosis on serosis and mucous membrane  exsudative pneumonia  Sub acute form  Petechia to ecchymosis in intestine, heart,lungs  exsudate in pericard and body cavity  swollen liver, coagulative necrosis(corn meal liver)  in turkey → frequently exsudative pneumonia  In turkey → flaccid, puckered a hyperemic follicle on ovary
  14. 14. Fowl cholera. Small areas of necrosis in the liver (corn meal liver)
  15. 15. hyperemic
  16. 16. Hemorrhage in heart muscle Haemorrhages in intestine (different extent)
  17. 17. Wattle form, artritis, osteomyelitis Exsudative serositis sinusitis
  18. 18. Purulent exudate may be found within the facial swellings
  19. 19. The foot has been incised to show a caseous exudate .
  20. 20. 1.history, sings and lesions 2.bacteriology 3.indentification by using biochemical test 4.now is available PCR test 5.bipolar microorganismus by bluedomethylene staining 6.Serology AGID or ELISA, better for evaluation of vaccine response
  21. 21. Bluedomethylene,lichman,gimsa staining→bipolar bacteria Heart and livers blood Culture in : dextrose starch agar +5%serum Morphology on D.S.A: 1- Fluorescent→high virolent 2-sectored colony→mild 3-blue or slightly fluorescent→low 4-non fluorescent→non pathogene MUSSY ODOR
  22. 22. 1.Infectious coryza 2.Fowl typhoid 3.Fowl plague(avian flu) 4.Duck plaque(duck herpes virus 1) 5.Otherpaseurellas(p.haemolitica,p.gallinarm)
  23. 23. 1-Wild birds 2-Rodents 3-cat.dog,pigs,… 4-Vaccination
  24. 24. 1 -live attenuated 2-in activated : razi institute A: 1 Best→(-):1,3,4 Age : 8-10 and 18-20 w In poultry →IM In turkey →DW
  25. 25. 1-Sulfa drugs 2-Semisynthetic penicillins 3-Tertracyclines 4-Erythromycin
  26. 26. Thanks

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