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Case presentation
Dr. Samten Dorji
Chief complaint
• A 27 year old woman presented to the eye
OPD clinic with weakness in left side of
face for 2 weeks duration
She is a monk from Punakha dzongkhag
History of chief complaint
• 2 weeks back she had a sudden onset of
left side facial weakness and pain in the
left ear which lasted for first three days
• She had difficulty in closing her left eye
and had on and off watery discharge. She
complains of mild drooling.
• No previous episode
• There was no history of trauma
History cont.
• Systemic review
• Past ocular history/ocular
medications/systemic medications/
comorbidities/allergies/family history
Examination
• Asymmetry of the face
• Absent wrinkling of left forehead
• Inability to close left eye(lagophthalmus)
• Mouth deviated to the right side
• Unable to puff out left cheek
Right eye Left eye
Visual acuity 6/6 6/6
With pinhole
Color vision Normal Normal
Extraocular movements Normal Normal
Bell’s phenomenon Present
Lids and adnexa Normal Normal
Schirmer’s test 15mm 15mm
Conjunctiva and sclera normal normal
Cornea clear Clear( sensation intact)
Anterior chamber Normal depth and quiet Normal depth and quiet
Iris and lens Normal Normal
Pupil Round regular and
reactive
Round regular and
reactive
Dilated fundus Vessel sheathing and
healed scars
Normal
Case summary
• A 27 year old female presented with
weakness in left side of face for 2 weeks
with difficulty in closing the left eye and left
earache for initial 3 days.neurological
examination showed left lower motor
neuron seventh nerve palsy. Bell’s
phenomenon and corneal sensation was
intact. Dilated funduscopy showed vessel
sheathing and healed scars in the left
fundus.
Problems
• Left lower motor neuron seventh nerve
palsy
• Healed right retinal vasculitis
Diagnosis
• House-Brackmann grade 3 left lower
motor neuron facial nerve palsy with
idiopathic cause.
Differential diagnosis
• Infection
• Neoplasm
• Congenital
• Trauma
Investigation
Management
Corticosteroids
•Oral prednisolone 60mg daily for 7 days and tapered until 5mg daily
•Anti acid medications
•Early treatment is recommended especially within 3 days of symptoms of onset.
•Significantly reduced mild and moderate sequelae.
Facial physiotherapy
•To help in recovery of facial nerve function
•Prevents muscle atrophy and aids in full recovery if prognosis is good
Eye lubricants
•To prevent exposure keratopathy
•Depending upon the severity of keratopathy the frequency of lubricants is prescribed
ENT review
•Assessement was normal
•To rule out any pathology causing facial nerve palsy
Lower motor neuron facial
nerve palsy
Outline
• Introduction
• Anatomy
• Aetiology
• Clinical evaluation
• Management
Introduction
FunctionFunction PsychologyPsychology
EmotionEmotion
Anatomy
• Motor fibers that innervate the facial
muscles
• Parasympathetic fibers innervating
lacrimal, submandibular, and
sublingual salivary glands
• Afferent fibers from taste receptors
from the anterior two thirds of the
tongue
• Somatic afferents from the external
auditory canal and pinna
• The nerve arises from two roots from
the pontomedullary junction and
enters the internal auditory meatus
•The facial (fallopian) canal= 33 mm
•labyrinthine, tympanic, and mastoid
•Narrowest in the labyrinthine segment
(average 0.68 mm in diameter)
•Facial nerve emerge at the stylomastoid
foramen and pass through the parotid
gland
•These fibers divide into five groups of
nerves between the deep and superficial
lobes of the gland
Aetiology
• Idiopathic (Bell’s palsy)
• Trauma
• Infection
• Neoplasms
• Congenital
• Miscellaneous
Bell’s palsy
• Acute peripheral facial nerve palsy of unknown cause
• Diagnosis of exclusion
Epidemiology
•The annual incidence rate =13 and 34 cases per 100,000 population
•Age=15-45 years age group
•No race, geographic, or gender predilection
•Risk is three times greater during pregnancy
Pathophysiology
• Herpes simplex virus activation is the
likely cause of Bell's palsy in most cases
• Inflammatory and possibly infectious
cause
• Nerve damage is maximal in the
labyrinthine part of the facial canal
Trauma
• Second most common cause
• Most common is temporal bone
fractures(blunt and penetrating)
• Iatrogenic
Infection
• Varicella zoster virus
• Lyme disease
• Tuberculosis
• Polio
• Mumps
• leprosy
Ramsay hunt syndrome
•Geniculate ganglionitis
•Zoster vesicles in external auditory
canal or tympanic membrane(classic
sign)
Neoplasms
Congenital
Moebius syndrome
Digeorge syndrome
Coloboma
Heart defects
Atresia ofchoanae
Retardation of growth
Genital abnormalities
Ear abnormalities
Miscellaneous
• Diabetes mellitus
• Hypertension
• Amyloidosis
• Sarcoidosis
• Multiple sclerosis
• Guillain-Barre syndrome
• Myasthenia gravis
• Stroke
Clinical evaluation
Laboratory investigation
• VDRL screening
• Imaging studies
Management
• Medical
• Surgical
Risk factors for exposure keratopathy
•Absence of corneal sensation
•Severe lagophthalmus
•Absent bell’s phenomenon
•Dry eye
Medical
Avoid ocular
irritants
Avoid ocular
irritants
Spectacle side shields
Botulinum injection into
levator muscle
•Cyanoacrylate glue
•High dose of oral corticosteroids
External eyelid weights
Surgical treatment
• Management of corneal exposure
• Correction of lower eyelid ectropion
• Management of brow ptosis
• Management of chronic epiphora
Management of corneal exposure
Mullerectomy and
levator aponeurosis
recession
Mullerectomy and
levator aponeurosis
recession
Silicone punctal plugs
Temporary suture
tarsorrhaphy
Lateral tarsorrhaphy
Medial canthoplasty Gold weight implant
Correction of lower eyelid ectropion
Skin graft procedure
Mid face liftMid face lift
Lateral tarsal strip procedure
Management of brow ptosis
blepharoplasty
•Impairment of superior
visual field
•Cosmetic deformity
•Pseudo- blepharoptosis
Management of chronic epiphora
Dry eye
•eye lubricants
Paralytic ectropion
•Lateral eyelid tarsal strip
procedure
•Dacryocystorhinostomy and
jones tube insertion
Hypersecretion/aberrant
innervation
• Crocodile tear
syndrome(bogoraud’s
syndrome)
• Transconjunctival
intraglandular
Botulinum toxin A
injections
Summary
• Introduction
• Anatomy
• Aetiology
• Clinical evaluation
• Management
Take home message
• Facial paralysis can be difficult to manage
• Should exclude other causes before
labelling it as idiopathic
• Multidisciplinary approach
• Ophthalmologist role: eye protection and
aesthetic improvement
Thank you

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a case of lower motor neuron facial nerve palsy

  • 2. Chief complaint • A 27 year old woman presented to the eye OPD clinic with weakness in left side of face for 2 weeks duration She is a monk from Punakha dzongkhag
  • 3. History of chief complaint • 2 weeks back she had a sudden onset of left side facial weakness and pain in the left ear which lasted for first three days • She had difficulty in closing her left eye and had on and off watery discharge. She complains of mild drooling. • No previous episode • There was no history of trauma
  • 4. History cont. • Systemic review • Past ocular history/ocular medications/systemic medications/ comorbidities/allergies/family history
  • 5. Examination • Asymmetry of the face • Absent wrinkling of left forehead • Inability to close left eye(lagophthalmus) • Mouth deviated to the right side • Unable to puff out left cheek
  • 6.
  • 7.
  • 8. Right eye Left eye Visual acuity 6/6 6/6 With pinhole Color vision Normal Normal Extraocular movements Normal Normal Bell’s phenomenon Present Lids and adnexa Normal Normal Schirmer’s test 15mm 15mm Conjunctiva and sclera normal normal Cornea clear Clear( sensation intact) Anterior chamber Normal depth and quiet Normal depth and quiet Iris and lens Normal Normal Pupil Round regular and reactive Round regular and reactive Dilated fundus Vessel sheathing and healed scars Normal
  • 9. Case summary • A 27 year old female presented with weakness in left side of face for 2 weeks with difficulty in closing the left eye and left earache for initial 3 days.neurological examination showed left lower motor neuron seventh nerve palsy. Bell’s phenomenon and corneal sensation was intact. Dilated funduscopy showed vessel sheathing and healed scars in the left fundus.
  • 10. Problems • Left lower motor neuron seventh nerve palsy • Healed right retinal vasculitis
  • 11.
  • 12.
  • 13. Diagnosis • House-Brackmann grade 3 left lower motor neuron facial nerve palsy with idiopathic cause.
  • 14. Differential diagnosis • Infection • Neoplasm • Congenital • Trauma
  • 16.
  • 17. Management Corticosteroids •Oral prednisolone 60mg daily for 7 days and tapered until 5mg daily •Anti acid medications •Early treatment is recommended especially within 3 days of symptoms of onset. •Significantly reduced mild and moderate sequelae. Facial physiotherapy •To help in recovery of facial nerve function •Prevents muscle atrophy and aids in full recovery if prognosis is good
  • 18. Eye lubricants •To prevent exposure keratopathy •Depending upon the severity of keratopathy the frequency of lubricants is prescribed ENT review •Assessement was normal •To rule out any pathology causing facial nerve palsy
  • 19. Lower motor neuron facial nerve palsy
  • 20. Outline • Introduction • Anatomy • Aetiology • Clinical evaluation • Management
  • 22. Anatomy • Motor fibers that innervate the facial muscles • Parasympathetic fibers innervating lacrimal, submandibular, and sublingual salivary glands • Afferent fibers from taste receptors from the anterior two thirds of the tongue • Somatic afferents from the external auditory canal and pinna • The nerve arises from two roots from the pontomedullary junction and enters the internal auditory meatus
  • 23. •The facial (fallopian) canal= 33 mm •labyrinthine, tympanic, and mastoid •Narrowest in the labyrinthine segment (average 0.68 mm in diameter) •Facial nerve emerge at the stylomastoid foramen and pass through the parotid gland •These fibers divide into five groups of nerves between the deep and superficial lobes of the gland
  • 24.
  • 25. Aetiology • Idiopathic (Bell’s palsy) • Trauma • Infection • Neoplasms • Congenital • Miscellaneous
  • 26. Bell’s palsy • Acute peripheral facial nerve palsy of unknown cause • Diagnosis of exclusion Epidemiology •The annual incidence rate =13 and 34 cases per 100,000 population •Age=15-45 years age group •No race, geographic, or gender predilection •Risk is three times greater during pregnancy
  • 27. Pathophysiology • Herpes simplex virus activation is the likely cause of Bell's palsy in most cases • Inflammatory and possibly infectious cause • Nerve damage is maximal in the labyrinthine part of the facial canal
  • 28.
  • 29. Trauma • Second most common cause • Most common is temporal bone fractures(blunt and penetrating) • Iatrogenic
  • 30. Infection • Varicella zoster virus • Lyme disease • Tuberculosis • Polio • Mumps • leprosy
  • 31. Ramsay hunt syndrome •Geniculate ganglionitis •Zoster vesicles in external auditory canal or tympanic membrane(classic sign)
  • 33. Congenital Moebius syndrome Digeorge syndrome Coloboma Heart defects Atresia ofchoanae Retardation of growth Genital abnormalities Ear abnormalities
  • 34. Miscellaneous • Diabetes mellitus • Hypertension • Amyloidosis • Sarcoidosis • Multiple sclerosis • Guillain-Barre syndrome • Myasthenia gravis • Stroke
  • 36.
  • 37. Laboratory investigation • VDRL screening • Imaging studies
  • 38. Management • Medical • Surgical Risk factors for exposure keratopathy •Absence of corneal sensation •Severe lagophthalmus •Absent bell’s phenomenon •Dry eye
  • 39. Medical Avoid ocular irritants Avoid ocular irritants Spectacle side shields Botulinum injection into levator muscle
  • 40. •Cyanoacrylate glue •High dose of oral corticosteroids External eyelid weights
  • 41. Surgical treatment • Management of corneal exposure • Correction of lower eyelid ectropion • Management of brow ptosis • Management of chronic epiphora
  • 42. Management of corneal exposure Mullerectomy and levator aponeurosis recession Mullerectomy and levator aponeurosis recession Silicone punctal plugs Temporary suture tarsorrhaphy Lateral tarsorrhaphy Medial canthoplasty Gold weight implant
  • 43. Correction of lower eyelid ectropion Skin graft procedure Mid face liftMid face lift Lateral tarsal strip procedure
  • 44. Management of brow ptosis blepharoplasty •Impairment of superior visual field •Cosmetic deformity •Pseudo- blepharoptosis
  • 45. Management of chronic epiphora Dry eye •eye lubricants Paralytic ectropion •Lateral eyelid tarsal strip procedure •Dacryocystorhinostomy and jones tube insertion
  • 47. Summary • Introduction • Anatomy • Aetiology • Clinical evaluation • Management
  • 48. Take home message • Facial paralysis can be difficult to manage • Should exclude other causes before labelling it as idiopathic • Multidisciplinary approach • Ophthalmologist role: eye protection and aesthetic improvement