Peripheral nerve disorders

1. PERIPHERAL
NERVE DISORDER
Sanil Varghese

2. PERIPHERAL NEUROPATHIES
• Is defined as alteration in function and
structure of the motor, sensory or autonomic
components of a peripheral nerve.

3. CATEGORIES AND ETIOLOGIES OF
PERIPHERAL NEUROPATHIES
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Metabolic or nutritional.
Drug induced.
Industrial or environmental toxins.
Connective tissue processes or vasculitis.
Infections or infectious processes.
Inflammatory processes.
Neoplasms.
Trauma or compressions.
Entrapment syndromes.
Heriditory disorders.

4. PATHOPHYSIOLOGY
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Wallerian degeneration.
Axonal degeneration.
Primary neuronal degeneration.
Segmental demyelination.

5. DISTRIBUTION PATTERNS OF
PERIPHERAL NEUROPATHIES
• Mononeuropathy simplex or
mononeuropathy.
• Mononeuropathy multiplex.
• Polyneuropathy.

6. CLINICAL MANIFESTATIONS
• Pain, paresthesia, sensory loss, weakness, unstable
balance.
• Autonomic or trophic changes like cold, blue
extremities, cutaneous hair loss, brittle finger or
toenails.
• Decrease or a loss of light touch and pinprick
sensation.
• Tingling, numbness, paraesthesia and disesthesia.
• Neuropathic pain.
• Deep tendon reflexes absent or decreased in
affected muscels.

7. MONONEUROPATHY
Types
• Carpal tunnel syndrome
• Ulnar nerve palsy.
• Radial nerve palsy.
• Peroneal nerve palsy.

9. TINEL’S SIGN

10. PHALEN’S SIGN

11. Ulnar nerve palsy

12. MULTIPLE MONONEUROPATHY

13. POLYNEUROPATHY

14. DIABETIC NEUROPATHY