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© 2018 All Rights Reserved | Steve Ardire
AI Startups and Entrepreneurship
Steve Ardire
AI startup advisor 'force multiplier’ & 'Merchant of Light
sardire@gmail.com @sardire
http://www.linkedin.com/in/sardire
About Me:
Steve is AI startup advisor 'force multiplier' ( business strategy, funding, marketing, customer/partner
engagement ) who shapes serendipity to connect and illuminate the dots that matter ( aka The
Merchant of Light ). He leverages significant relationship capital and personal branding in AI space and
specialist for under appreciated, underestimated, underdog startups . Speaker at many AI events
whose favorite topic is #AugmentedIntelligence for #futureofwork so why https://www.bigspeak.com/
speakers/steve-ardire/. For more follow @sardire and connect on http://www.linkedin.com/in/sardire
my #Think2018 preso https://youtu.be/lqRDbrKP7k4 ( pinned tweet on @sardire ) now over 103,000
impressions and #AI Innovation in #Healthcare @mnmconferences #AI Healthcare Summit Oct 25 – 26
in Boston https://twitter.com/sardire/status/1057317403464425472
@AIWorldExpo Dec 3 - 5 in Boston https://aiworld.com moderating panels on #AugmentedIntelligence
& Cognitive Applications for #futureofwork https://aiworld.com/Cognitive-Computing/ and #AI Follow
the Money panel https://aiworld.com/ai-startup-pavilion-and-theater-presentations
© 2018 All Rights Reserved | Steve Ardire
some highlights @AIWorldExpo https://aiworld.com/ sessions Dec 3 - 5 in Boston
RT @lolitataub Steve is on fire. "Efficiency should be left to
machines. Effectiveness should be left to humans." - @sardire
#AIWorld https://twitter.com/lolitataub/status/
1070022843168100352 top tweet on #AIWorld
My #AIWorld panel sessions 
#AI Follow the Money
#AugmentedIntelligence & Cognitive Applications for #futureofwork
© 2018 All Rights Reserved | Steve Ardire
Healthcare organizations
investing big in #AI
https://goo.gl/e1aHMC
Health IT company Optum survey of healthcare organizations
• 94% agree #AI is most reliable path toward equitable, accessible, affordable healthcare
• 36% expect AI to improve patient experience
• 31% believe AI will improve health outcomes
Of healthcare organizations already investing in AI:
• 75% actively implementing or have plans to execute an AI strategy
• 22% have AI implementations at late stage with nearly full deployment.
• 42% have a strategy that has yet to be implemented.
• 90+% confident of strong ROI with avg AI investment of $32.4 million over next 5 yrs
• 42% using AI to automate business processes
• 36% are using it to detect patterns of fraud, waste and abuse
• 31% are using it to monitor users with Internet of Things (IoT) devices
© 2018 All Rights Reserved | Steve Ardire
Top 8 #Healthcare Predictions for 2019
https://www.forbes.com/sites/reenitadas/2018/11/13/top-8-healthcare-predictions-for-2019/#6e05b8fa700e
© 2018 All Rights Reserved | Steve Ardire
The Innovation Health Care
Really Needs: Help People
Manage Their Own Health
https://hbr.org/2017/10/the-innovation-
health-care-really-needs-help-people-manage-
their-own-health
More than $200 billion has been
poured into health care venture
capital, mostly in biotech, pharma,
and devices where advances
typically make health care more
sophisticated — and expensive.
Less than 1% of those
investments have focused on
helping consumers to play a more
active role in managing their own
health, an area ripe for disruptive
approaches.
© 2018 All Rights Reserved | Steve Ardire
So how do you get an
invite to this party 🎷
📣🎶 ?
© 2018 All Rights Reserved | Steve Ardire
FIRST YOU NEED A VERY COMPELLING PITCH ( or you’re DOA )
1) Company Purpose
2) Problem
3) Solution
4) Why Now and Market Size
based on answers to 1) to 3) so if they’re not really good hard to make compelling for interest
5) Product
LOL if you’re a ‘me too’ product
6) Competition
7) Business Model
point 4) startups fail because you’re making something no one wants to use or buy have a
business model that is not viable or scaleable
8) Customer Use Cases
if you’re not in “the club” must have enough early adopters that paid for POC
9) Core Team ( include key advisors )
VC’s invest in people first
10) Financials, Valuation, Ask ( Funding Amount )
if you’re not in “the club” typically need $25K MRR to close $250K seed
Valuation: for AI seed funding valuation at 5 - 8X revenue + $2M
© 2018 All Rights Reserved | Steve Ardire
My POV on funding as AI startup advisor
"PRE-SEED" SEED /SEED + SERIES A SERIES B
Round Size $250k - $500K $1M - $3M $5M - $15M $20m - $40m
MRR < $25K $50k - $150K $500K - $1M > $3M
Valuation $1M - $4M $5 - $10M $15M - $40M $70m - $200m
Funding
Sources
Founders, Friends &
Family Accelerator /
Incubator
Angels, Micro VCs MicroVCs, VC’s Growth VCs,
Private Equity
Team Core team with strong
tech cofounder and great
advisors a plus
Add dev team to build robust
product plus marketing/bus dev
+ advisors with proven startup
experience
Add marketing/sales pros who
for smart tactical execution
to scale & great advisors still a
plus ;-)
excellent
leadership
with smart
tactical execution
in all departments
Traction and
Product/
Market Fit
( PMF )
Have MVP for
Early adopters ( 3 - 6 )
preferably with paid POCs
some of which can serve
as references
Go-to-market strategy with CVP
for customer traction with
Product dev prioritization
marketing drives sales for PMF
to monetize demand with
scalable customer acquisition
across verticals including
reseller and OEM
Clear PMF in
multiple verticals
with scalability of
growth/marketing
machine.
Observations
& Advice
9 of 10 startups fail
Must have mindset with
grit, creativity,
determination, competitive
zeal
From get go find right
investors who are excited
and add value besides $$$
or your journey may suck !
raise what you need need to
make progress,
VCs seek high velocity, 5x - 10x
returns in 3 yrs so are you
venture scale?
Be rigorous with VC’s as they are
with you !
learn from rejection ask for
feedback
Hardest thing is finding product-
market fit then building ruthless
machine to acquire, monetize,
retain them.
My advice is get to $10M annual
sales with $10M funding max
( you have $100M valuation so
what’s not to like ) get acquired
then do next startup
If you’re not
acquired after
Series A raise nice
Series B and really
scale or else your
VC’s will hate you !
© 2018 All Rights Reserved | Steve Ardire
The Top 20 Reasons Startups Fail https://www.cbinsights.com/research/startup-failure-reasons-top
much higher
product/market fit
tie lineseven well funded startups
super competitive
much higher
been here
conjoin these
© 2018 All Rights Reserved | Steve Ardire
“What’s it like to be a female tech entrepreneur?” via @TheRealFreada
https://medium.com/kapor-the-bridge/whats-it-like-to-be-a-female-tech-entrepreneur-a170a99089eb
• The good news is women who accuse men of unwelcome behavior now
generally believed at the outset. That’s a forward movement.
• Bad news is much of conversation ignores marginalized and vulnerable
backgrounds (women of color, LGBTQ women, immigrant women, low-
income women, etc.) despite decades of scholarship on intersectionality
and #whitefeminism. That’s a giant step backwards.
• VCs Don’t Compare Me To Your Wife, Just Don’t https://inc42.com/
entrepreneurship/vcs-dont-compare-me-to-your-wife-just-dont via
@sarahnadav
progress but two steps forward, one step back, one step sideways.
Melinda Gates has sharp words for VC’s
Enough with your love for 'the white guy
in a hoodie' https://read.bi/2Ldy3Rx
Backstage Capital recently announced
$36 million fund for a that will invest
solely in black women founders
Start-ups founded by women generate
more revenue and do it with less
funding https://wef.ch/2JA6UM7
More good news
© 2018 All Rights Reserved | Steve Ardire
AGI
Causal inference looks into root causes to address
understanding and perceptions and Why
Explainable AI ( XAI ) is Hot !
THE REAL VALUE IS AUGMENTED INTELLIGENCE
1. AI as capable ( and more capable than doctors ) in diagnosing patients. 
2. AI better than humans at predicting health events before they happen.
3. AI can make sense of huge amounts of data that would be overwhelming to humans
or exactly what’s needed in growing field of precision medicine
• ML alone for mammograms 80% to 90% precision ( similar to doctors ) but combined with
professional expertise accuracy reaches 95%
• ML to personalize cancer treatment allow doctors to predict where killer disease will spread
• New #AI system can screen for neurological illnesses in seconds
• AI system correctly refers patients with more than 50 different eye diseases for further treatment
with 94% accuracy, matching or beating world-leading eye specialists
• AI can spot pain from a disease some doctors still think is fake
• Artificial Emotional Intelligence for detection, treatment, management of cognitive impairments
delirium and dementia.
• SWARM Intelligence: Combining The Hive Mind With AI For Better Diagnoses
Augmented intelligence will deliver “why”
with shaper insight, relevance, speed.
@Soulmachines ( Auckland NZ ) digital humans can learn and react in real time
https://twitter.com/Soulmachines/status/1054455925493223424 and
engineering AI to mimic the human brain and body https://twitter.com/futurism/
status/1007292893680295937
Lessons learned from some of my AI advisor gigs
© 2018 All Rights Reserved | Steve Ardire
@emawware ( Montreal ) touchscreen emotion analytics https://emaww.com/
@robbie_ai ( Boston ) facial recognition and human emotion assessment in natural settings. AI-
Based Facial Recognition @robbie_ai and Security Technology @SureID to develop Holistic
nationwide #biometric capture system for consumer initiatives https://zd.net/2Pakpos
@EmoShape ( NYC ) Emotion synthesis – The Future of
Robotics and virtual agents
https://twitter.com/EmoShape/status/992020942183387136
http://exclone.com ( NYC ) Expert Chatbots using Digital Cloning Technology and http://drchat.ai/
@CogWorldHub Knowledge Hub, Ecosystem, Marketplace for AI transformation
https://cognitiveworld.com and https://www.cogworldhub.com
SHARK TANK SPONSOR whose prize is FREE 1 year $5K Membership to winner !
Ray Kurzweil: computers
will match or beat human
intelligence with emotions
& sense of humor
Amazon In #Healthcare: The E-Commerce Giant’s Strategy For A $3 Trillion Market
https://www.cbinsights.com/research/report/amazon-transforming-healthcare
Amazon, #AI and Medical Records: Do the Benefits Outweigh the Risks?
http://knowledge.wharton.upenn.edu/article/amazon-medical-records/
Amazon knows how to handle and analyze data. It’s a $3.5 trillion industry and 18% of our
economy, so who wouldn’t want a piece of that but this comes with privacy and other concerns.
Conclusion
Amazon’s potential foray into healthcare has already caused players in the space to scramble and
reevaluate their core competencies. While Amazon has barely scratched healthcare’s surface, it
has the potential to upend the space with its e-commerce expertise. Without the need to make
money in healthcare, the high margin and convoluted parts of the healthcare business are ripe for
disruption.
Amazon’s approach allows other companies to outsource parts of their businesses that are messy
and outside their main focus. This can happen on multiple fronts, impacting:
• Payers — Amazon can handle the claims and marketplace so companies can focus on offering
their services.
• Providers — Amazon can handle documentation into the EMR or coordinating buying and
transporting supplies.
• Pharma/Biotech — Amazon can run the actual experiments so researchers can focus on
experiment design and analysis; or Amazon can handle the packaging, tracking, and
transportation for larger drug manufacturers.
@sardire preso for AIMed @ai_in_medicine #aimedna startup workshop
© 2018 All Rights Reserved | Steve Ardire
Steve Ardire
AI startup advisor 'force multiplier’ & 'Merchant of Light
sardire@gmail.com @sardire
http://www.linkedin.com/in/sardire
Steve is AI startup advisor 'force multiplier' ( business strategy, funding, marketing, customer/partner
engagement ) who shapes serendipity to connect and illuminate the dots that matter ( aka The
Merchant of Light ). He leverages significant relationship capital and personal branding in AI space
and specialist for under appreciated, underestimated, underdog startups . Speaker at many AI events
whose favorite topic is #AugmentedIntelligence for #futureofwork so why https://
www.bigspeak.com/speakers/steve-ardire/.
For more follow @sardire and connect on http://www.linkedin.com/in/sardire

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@sardire preso for AIMed @ai_in_medicine #aimedna startup workshop

  • 1. © 2018 All Rights Reserved | Steve Ardire AI Startups and Entrepreneurship Steve Ardire AI startup advisor 'force multiplier’ & 'Merchant of Light sardire@gmail.com @sardire http://www.linkedin.com/in/sardire About Me: Steve is AI startup advisor 'force multiplier' ( business strategy, funding, marketing, customer/partner engagement ) who shapes serendipity to connect and illuminate the dots that matter ( aka The Merchant of Light ). He leverages significant relationship capital and personal branding in AI space and specialist for under appreciated, underestimated, underdog startups . Speaker at many AI events whose favorite topic is #AugmentedIntelligence for #futureofwork so why https://www.bigspeak.com/ speakers/steve-ardire/. For more follow @sardire and connect on http://www.linkedin.com/in/sardire my #Think2018 preso https://youtu.be/lqRDbrKP7k4 ( pinned tweet on @sardire ) now over 103,000 impressions and #AI Innovation in #Healthcare @mnmconferences #AI Healthcare Summit Oct 25 – 26 in Boston https://twitter.com/sardire/status/1057317403464425472 @AIWorldExpo Dec 3 - 5 in Boston https://aiworld.com moderating panels on #AugmentedIntelligence & Cognitive Applications for #futureofwork https://aiworld.com/Cognitive-Computing/ and #AI Follow the Money panel https://aiworld.com/ai-startup-pavilion-and-theater-presentations
  • 2. © 2018 All Rights Reserved | Steve Ardire some highlights @AIWorldExpo https://aiworld.com/ sessions Dec 3 - 5 in Boston RT @lolitataub Steve is on fire. "Efficiency should be left to machines. Effectiveness should be left to humans." - @sardire #AIWorld https://twitter.com/lolitataub/status/ 1070022843168100352 top tweet on #AIWorld My #AIWorld panel sessions  #AI Follow the Money #AugmentedIntelligence & Cognitive Applications for #futureofwork
  • 3. © 2018 All Rights Reserved | Steve Ardire Healthcare organizations investing big in #AI https://goo.gl/e1aHMC Health IT company Optum survey of healthcare organizations • 94% agree #AI is most reliable path toward equitable, accessible, affordable healthcare • 36% expect AI to improve patient experience • 31% believe AI will improve health outcomes Of healthcare organizations already investing in AI: • 75% actively implementing or have plans to execute an AI strategy • 22% have AI implementations at late stage with nearly full deployment. • 42% have a strategy that has yet to be implemented. • 90+% confident of strong ROI with avg AI investment of $32.4 million over next 5 yrs • 42% using AI to automate business processes • 36% are using it to detect patterns of fraud, waste and abuse • 31% are using it to monitor users with Internet of Things (IoT) devices
  • 4. © 2018 All Rights Reserved | Steve Ardire Top 8 #Healthcare Predictions for 2019 https://www.forbes.com/sites/reenitadas/2018/11/13/top-8-healthcare-predictions-for-2019/#6e05b8fa700e
  • 5. © 2018 All Rights Reserved | Steve Ardire The Innovation Health Care Really Needs: Help People Manage Their Own Health https://hbr.org/2017/10/the-innovation- health-care-really-needs-help-people-manage- their-own-health More than $200 billion has been poured into health care venture capital, mostly in biotech, pharma, and devices where advances typically make health care more sophisticated — and expensive. Less than 1% of those investments have focused on helping consumers to play a more active role in managing their own health, an area ripe for disruptive approaches.
  • 6. © 2018 All Rights Reserved | Steve Ardire So how do you get an invite to this party 🎷 📣🎶 ?
  • 7. © 2018 All Rights Reserved | Steve Ardire FIRST YOU NEED A VERY COMPELLING PITCH ( or you’re DOA ) 1) Company Purpose 2) Problem 3) Solution 4) Why Now and Market Size based on answers to 1) to 3) so if they’re not really good hard to make compelling for interest 5) Product LOL if you’re a ‘me too’ product 6) Competition 7) Business Model point 4) startups fail because you’re making something no one wants to use or buy have a business model that is not viable or scaleable 8) Customer Use Cases if you’re not in “the club” must have enough early adopters that paid for POC 9) Core Team ( include key advisors ) VC’s invest in people first 10) Financials, Valuation, Ask ( Funding Amount ) if you’re not in “the club” typically need $25K MRR to close $250K seed Valuation: for AI seed funding valuation at 5 - 8X revenue + $2M
  • 8. © 2018 All Rights Reserved | Steve Ardire My POV on funding as AI startup advisor "PRE-SEED" SEED /SEED + SERIES A SERIES B Round Size $250k - $500K $1M - $3M $5M - $15M $20m - $40m MRR < $25K $50k - $150K $500K - $1M > $3M Valuation $1M - $4M $5 - $10M $15M - $40M $70m - $200m Funding Sources Founders, Friends & Family Accelerator / Incubator Angels, Micro VCs MicroVCs, VC’s Growth VCs, Private Equity Team Core team with strong tech cofounder and great advisors a plus Add dev team to build robust product plus marketing/bus dev + advisors with proven startup experience Add marketing/sales pros who for smart tactical execution to scale & great advisors still a plus ;-) excellent leadership with smart tactical execution in all departments Traction and Product/ Market Fit ( PMF ) Have MVP for Early adopters ( 3 - 6 ) preferably with paid POCs some of which can serve as references Go-to-market strategy with CVP for customer traction with Product dev prioritization marketing drives sales for PMF to monetize demand with scalable customer acquisition across verticals including reseller and OEM Clear PMF in multiple verticals with scalability of growth/marketing machine. Observations & Advice 9 of 10 startups fail Must have mindset with grit, creativity, determination, competitive zeal From get go find right investors who are excited and add value besides $$$ or your journey may suck ! raise what you need need to make progress, VCs seek high velocity, 5x - 10x returns in 3 yrs so are you venture scale? Be rigorous with VC’s as they are with you ! learn from rejection ask for feedback Hardest thing is finding product- market fit then building ruthless machine to acquire, monetize, retain them. My advice is get to $10M annual sales with $10M funding max ( you have $100M valuation so what’s not to like ) get acquired then do next startup If you’re not acquired after Series A raise nice Series B and really scale or else your VC’s will hate you !
  • 9. © 2018 All Rights Reserved | Steve Ardire The Top 20 Reasons Startups Fail https://www.cbinsights.com/research/startup-failure-reasons-top much higher product/market fit tie lineseven well funded startups super competitive much higher been here conjoin these
  • 10. © 2018 All Rights Reserved | Steve Ardire “What’s it like to be a female tech entrepreneur?” via @TheRealFreada https://medium.com/kapor-the-bridge/whats-it-like-to-be-a-female-tech-entrepreneur-a170a99089eb • The good news is women who accuse men of unwelcome behavior now generally believed at the outset. That’s a forward movement. • Bad news is much of conversation ignores marginalized and vulnerable backgrounds (women of color, LGBTQ women, immigrant women, low- income women, etc.) despite decades of scholarship on intersectionality and #whitefeminism. That’s a giant step backwards. • VCs Don’t Compare Me To Your Wife, Just Don’t https://inc42.com/ entrepreneurship/vcs-dont-compare-me-to-your-wife-just-dont via @sarahnadav progress but two steps forward, one step back, one step sideways. Melinda Gates has sharp words for VC’s Enough with your love for 'the white guy in a hoodie' https://read.bi/2Ldy3Rx Backstage Capital recently announced $36 million fund for a that will invest solely in black women founders Start-ups founded by women generate more revenue and do it with less funding https://wef.ch/2JA6UM7 More good news
  • 11. © 2018 All Rights Reserved | Steve Ardire
  • 12. AGI Causal inference looks into root causes to address understanding and perceptions and Why Explainable AI ( XAI ) is Hot ! THE REAL VALUE IS AUGMENTED INTELLIGENCE 1. AI as capable ( and more capable than doctors ) in diagnosing patients.  2. AI better than humans at predicting health events before they happen. 3. AI can make sense of huge amounts of data that would be overwhelming to humans or exactly what’s needed in growing field of precision medicine • ML alone for mammograms 80% to 90% precision ( similar to doctors ) but combined with professional expertise accuracy reaches 95% • ML to personalize cancer treatment allow doctors to predict where killer disease will spread • New #AI system can screen for neurological illnesses in seconds • AI system correctly refers patients with more than 50 different eye diseases for further treatment with 94% accuracy, matching or beating world-leading eye specialists • AI can spot pain from a disease some doctors still think is fake • Artificial Emotional Intelligence for detection, treatment, management of cognitive impairments delirium and dementia. • SWARM Intelligence: Combining The Hive Mind With AI For Better Diagnoses Augmented intelligence will deliver “why” with shaper insight, relevance, speed.
  • 13. @Soulmachines ( Auckland NZ ) digital humans can learn and react in real time https://twitter.com/Soulmachines/status/1054455925493223424 and engineering AI to mimic the human brain and body https://twitter.com/futurism/ status/1007292893680295937 Lessons learned from some of my AI advisor gigs © 2018 All Rights Reserved | Steve Ardire @emawware ( Montreal ) touchscreen emotion analytics https://emaww.com/ @robbie_ai ( Boston ) facial recognition and human emotion assessment in natural settings. AI- Based Facial Recognition @robbie_ai and Security Technology @SureID to develop Holistic nationwide #biometric capture system for consumer initiatives https://zd.net/2Pakpos @EmoShape ( NYC ) Emotion synthesis – The Future of Robotics and virtual agents https://twitter.com/EmoShape/status/992020942183387136 http://exclone.com ( NYC ) Expert Chatbots using Digital Cloning Technology and http://drchat.ai/ @CogWorldHub Knowledge Hub, Ecosystem, Marketplace for AI transformation https://cognitiveworld.com and https://www.cogworldhub.com SHARK TANK SPONSOR whose prize is FREE 1 year $5K Membership to winner ! Ray Kurzweil: computers will match or beat human intelligence with emotions & sense of humor
  • 14. Amazon In #Healthcare: The E-Commerce Giant’s Strategy For A $3 Trillion Market https://www.cbinsights.com/research/report/amazon-transforming-healthcare Amazon, #AI and Medical Records: Do the Benefits Outweigh the Risks? http://knowledge.wharton.upenn.edu/article/amazon-medical-records/ Amazon knows how to handle and analyze data. It’s a $3.5 trillion industry and 18% of our economy, so who wouldn’t want a piece of that but this comes with privacy and other concerns. Conclusion Amazon’s potential foray into healthcare has already caused players in the space to scramble and reevaluate their core competencies. While Amazon has barely scratched healthcare’s surface, it has the potential to upend the space with its e-commerce expertise. Without the need to make money in healthcare, the high margin and convoluted parts of the healthcare business are ripe for disruption. Amazon’s approach allows other companies to outsource parts of their businesses that are messy and outside their main focus. This can happen on multiple fronts, impacting: • Payers — Amazon can handle the claims and marketplace so companies can focus on offering their services. • Providers — Amazon can handle documentation into the EMR or coordinating buying and transporting supplies. • Pharma/Biotech — Amazon can run the actual experiments so researchers can focus on experiment design and analysis; or Amazon can handle the packaging, tracking, and transportation for larger drug manufacturers.
  • 16. © 2018 All Rights Reserved | Steve Ardire Steve Ardire AI startup advisor 'force multiplier’ & 'Merchant of Light sardire@gmail.com @sardire http://www.linkedin.com/in/sardire Steve is AI startup advisor 'force multiplier' ( business strategy, funding, marketing, customer/partner engagement ) who shapes serendipity to connect and illuminate the dots that matter ( aka The Merchant of Light ). He leverages significant relationship capital and personal branding in AI space and specialist for under appreciated, underestimated, underdog startups . Speaker at many AI events whose favorite topic is #AugmentedIntelligence for #futureofwork so why https:// www.bigspeak.com/speakers/steve-ardire/. For more follow @sardire and connect on http://www.linkedin.com/in/sardire