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Revisioning &
Recapturing E.B.P:
Dialectical Behavior Therapy (DBT) as Example



          Scott D. Miller, Ph.D.
Dialectical Behavior Therapy (DBT):
•Defined as, “a mode of treatment designed for people with
borderline personality disorder (BPD)”;
    •Aims to help people to validate their emotions and behaviors,
    examine the negative impact of emotions and behaviors on their lives,
    and make a conscious effort to bring about positive change.

•Currently identified by professional organizations, funding
bodies, and government agencies as an “evidence-based,”
“empirically-supported,” “best practice.”


                      http://www.medterms.com/script/main/art.asp?articlekey=34212
                      http://www.apa.org/divisions/div12/cppi.html
                      http://www.mhreform.org/policy/ebs.htm
•Recommend that “consumers seek out
that have been studied and show to be
beneficial in controlled studies”;
•Empirically supported therapies meet
several “stringent” criteria:
     •Controlled (randomization, manuals,
     equality in delivery);
     •Results better than no treatment;
     •Results equal to an alternative
     treatment;
     •More than one study by more than
     one researcher or team.


             http://www.apa.org/divisions/div12/cppi.html
             http://www.mhreform.org/policy/ebs.htm
DBT:
                            What do the data say?

                             •Currently 15 studies published on
                             DBT (1991-2006);
                             •Nine of the fifteen qualify as
                             “randomized clinical trials” (RCT);
                             •Three of the nine RCT’s were
                             conducted by researchers other than
                             the developer.



http://depts.washington.edu/brtc/sharing/publications/research-and-
articles-on-dialectical-behavior-therapy
DBT:
What do the data say?

  •All of these studies but one compared
  the approach to “treatment as usual” or
  wait-list control;
  •The one study compared DBT to an
  approach that “proscribed use of
  cognitive-behavioral change
  techniques or any overt suggestion of
  new behaviors or advice about what to
  do.” (p. 16)
  •An example…


     Linehan, M.M., Dimeff, L.A., Reynolds, S.K., Comtois, K.A., Welch, S.S.,
     Heagerty, P., Kivlahan, D.R. (2002). Dialectical behavior therapy versus
     comprehensive validation plus 12-step for the treatment of opioid dependent
     women meeting criteria for borderline personality disorder. Drug and Alcohol
     Dependence, 67(1), 13-26.
DBT:
                               What do the data say?




                                              •NIMH funded study of DBT:
                                                    • Compared   DBT to services
                                                    offered by “community-
                                                    nominated” treatment experts;




Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow
up of DBT. Archives of General Psychiatry, 63, 757-766.
DBT:
                               What do the data say?
                                                    •DBT therapists:
                                                          •Received 45 hours of specialized
                                                          training;
                                                          •Pre- and during-study supervision.
                                                          •Gave 38 more hours of contact
                                                          dedicated to keeping people out of
                                                          the hospital
                                                    • Community         experts:
                                                          •Received no training, supervision, or
                                                          consultation;
                                                          •No control of type, amount, or quality
                                                          of services .
                                                          •Provided significantly less direct
                                                          service than DBT therapists.

Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow
up of DBT. Archives of General Psychiatry, 63, 757-766.
Vari-ability between Therapists:
                                    What do the data say?

                                                      “When individuals,
                                                      based on their
                                                      extensive experience
                                                      and reputation, are
                                                      nominated by their
                                                      peers as experts, their
                                                      actual performance
                                                      is…found to be
                                                      unexceptional…”.

Ericsson, K.A. (2006). The influence of expertise and deliberate practice
on the development of expert performance. In K.A. Ericcson, N.
Charness, P.J. Feltovich, & R.R. Hoffman (eds.). The Cambridge
Handbook of Expertise and Expert Performance (pp. 683-704). New York:
Cambridge University Press.
DBT:
                               What do the data say?




Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow
up of DBT. Archives of General Psychiatry, 63, 757-766.
DBT:
                               What do the data say?




Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow
up of DBT. Archives of General Psychiatry, 63, 757-766.
Study              RCT         Comparision                    Gender    Race & Ethnicity       Age          Drop out rate           Participants
                                      Group                                                                       (DBT/other)


Linnehan et al.       Yes          Treatment as usual      100% female      Not reported        18-45         4/24 (16.7%) v. 6/12      24/24
1991                               (Dosing not                                                                (50%)
BPD                                reported)                                                                  1 Suicide

Linnehan et al.       Yes          Treatment as usual      100% Female      Not reported        18-45         3/13 (23%)                13/13
1994                               (Dosing not                                                  Mean = 26     1 suicide v. 0
BPD                                reported)

Linnehan et al.       Yes          Treatment as usual      100% female      78% White           18-45         5/12 (41.6%)              12/16
1999                               (significantly lower                     11% Unspecified     Mean = 30     1 death v. 0
BDP/Drug                           dose)                                    7% Black                          D.O. in TAU dropped
                                   DBT received 2X                          4% Hispanic                       out prior to treatment
                                   as much therapy


Linnehan et al.       Yes          DBT plus 12 steps       100% female      87% White           28-43         4/11 (36%) v. 0/12        11/12
2002                                                                        12% Unspecified     Mean = 36
BPD/Drug

Koons et al. 2001     Yes          Treatment as usual      100% female      75% White           31-46         3/14 (21%) v. 2/14        14/14
BPD                                (significantly lower                     25% Black                         (14%)
                                   dose)

Van den Bosch et      Yes          Treatment as usual      100% Female      Not reported        Mean = 37.5   14/31 (45%) v. 20/27      31/27
al 2002                            (significantly lower                                                       (74%)
Verheul et al. 2003                dose)
BPD/Drug

Telch et al. 2001     Yes          Wait list control       100% Female      94% White           Mean = 50     4/22 (18%) v. 6/22        22/22
Binge Eating                                                                6% Unspecified                    (27%)

Safer et al. 2001     Yes          Wait list control       100% Female      87% White           18-54         2/14 (14%) v. 1/15 (7%)   14/15
Bulimia                                                                     13% Unspecified     Mean = 34

Lynch et al. 2003     Partial (n   Medication v. Meds      85% Female       85% White           66-80         Not reported              17/17
Depression            = 4)         plus DBT                15% Male         9% Black            Mean = 66
                                   (significantly higher                    6% Hispanic
                                   dose)

Linnehan et al.       Yes          Community               100% Female      86% White           18-45         11.5% v. 28.6%            52/49
2006                               nominated experts                        3.8% Black          Mean = 29
BPD                                                                         Asian 1.9%
                                                                            Other 5.8%

TOTAL                 8.5          1 semi-           BPD = 100% Female       81.5% White          18-45       25.9 v. 35.6%
   Allegiance                      direct                                                         Mean = 31.7                            BPD =
                                   comparison
                                           http://www.nrepp.samhsa.gov/programfulldetails.asp?PROGRAM_ID=72                               157
DBT:
            What can we conclude?

1. Extremely small and restricted sample (n = 157;
   100% female, 81% White);
2. Allegiance effects in 7/9 studies;
3. No real direct comparisons with another bonafide
   therapy;
4. Inequalities in dose and intensity of services;
5. No control over known confounds and contributors
   (especially, therapist and alliance effects).
What Works in Therapy:
                                 Direct Comparisons & Allegiance Effects
                                 Direct Comparisons & Allegiance Effects

                                                                                   •Meta-analysis of all
                                                                                   studies published between
                                                                                   1980-2006 comparing
                                                                                   bona fide treatments for
                                                                                   children with ADHD,
                                                                                   conduct disorder, anxiety,
                                                                                   or depression:
                                                                                            •No difference in outcome
                                                                                            between approaches intended
                                                                                            to be therapeutic;
                                                                                            •Researcher allegiance
                                                                                            accounted for 100% of
                                                                                            variance in effects.

Miller, S.D., Wampold, B.E., & Varhely, K. (2008). Direct comparisons of treatment modalities for youth disorders: A meta-analysis. Psychotherapy Research, 18(1), 5-14
What Works in Therapy:
    Alliance & Therapist Effects

        Researchers found SFT superior to TFP in
        work with borderline-diagnosed clients:
             •Significant differences in outcome
             between therapists;
             •Alliance significant predictor of retention
             and improvement, independent of
             outcome;

             •“In the more semistructured and long-
             term treatment of Axis II disorders, the
             development and maintenance of the
             therapeutic alliance constitutes a central
             issue of therapy and may constitute a
             central curing mechanism.”

          Spinhoven, P. et al. (2007). The therapeutic alliance in schema-focused
          therapy and transference-focused psychotherapy for borderline personality
          disorder. Journal of Consulting and Clinical Psychology, 75(1), 104-115.
Smoke and Mirrors
                   Real World Applications
DBT for “BPD”
• In a large CMHC serving
  SPMI clients: Of 382
  eligible by dx, only 25
  (6.5%) thought it was for
  them; 25% of those
  dropped out before
  program started; another
  25% dropped out…is it
  worth the cost?         Haynes, M. (2006). Real world applications of evidence based practice.
                                          Heart and Soul of Change 3. Bar Harbor, ME.
DBT:
   What can we conclude?


Doing
        ~
Better  =      D.B.T.

Therapy

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Dbt Handouts 2009

  • 1. Revisioning & Recapturing E.B.P: Dialectical Behavior Therapy (DBT) as Example Scott D. Miller, Ph.D.
  • 2. Dialectical Behavior Therapy (DBT): •Defined as, “a mode of treatment designed for people with borderline personality disorder (BPD)”; •Aims to help people to validate their emotions and behaviors, examine the negative impact of emotions and behaviors on their lives, and make a conscious effort to bring about positive change. •Currently identified by professional organizations, funding bodies, and government agencies as an “evidence-based,” “empirically-supported,” “best practice.” http://www.medterms.com/script/main/art.asp?articlekey=34212 http://www.apa.org/divisions/div12/cppi.html http://www.mhreform.org/policy/ebs.htm
  • 3. •Recommend that “consumers seek out that have been studied and show to be beneficial in controlled studies”; •Empirically supported therapies meet several “stringent” criteria: •Controlled (randomization, manuals, equality in delivery); •Results better than no treatment; •Results equal to an alternative treatment; •More than one study by more than one researcher or team. http://www.apa.org/divisions/div12/cppi.html http://www.mhreform.org/policy/ebs.htm
  • 4. DBT: What do the data say? •Currently 15 studies published on DBT (1991-2006); •Nine of the fifteen qualify as “randomized clinical trials” (RCT); •Three of the nine RCT’s were conducted by researchers other than the developer. http://depts.washington.edu/brtc/sharing/publications/research-and- articles-on-dialectical-behavior-therapy
  • 5. DBT: What do the data say? •All of these studies but one compared the approach to “treatment as usual” or wait-list control; •The one study compared DBT to an approach that “proscribed use of cognitive-behavioral change techniques or any overt suggestion of new behaviors or advice about what to do.” (p. 16) •An example… Linehan, M.M., Dimeff, L.A., Reynolds, S.K., Comtois, K.A., Welch, S.S., Heagerty, P., Kivlahan, D.R. (2002). Dialectical behavior therapy versus comprehensive validation plus 12-step for the treatment of opioid dependent women meeting criteria for borderline personality disorder. Drug and Alcohol Dependence, 67(1), 13-26.
  • 6. DBT: What do the data say? •NIMH funded study of DBT: • Compared DBT to services offered by “community- nominated” treatment experts; Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow up of DBT. Archives of General Psychiatry, 63, 757-766.
  • 7. DBT: What do the data say? •DBT therapists: •Received 45 hours of specialized training; •Pre- and during-study supervision. •Gave 38 more hours of contact dedicated to keeping people out of the hospital • Community experts: •Received no training, supervision, or consultation; •No control of type, amount, or quality of services . •Provided significantly less direct service than DBT therapists. Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow up of DBT. Archives of General Psychiatry, 63, 757-766.
  • 8. Vari-ability between Therapists: What do the data say? “When individuals, based on their extensive experience and reputation, are nominated by their peers as experts, their actual performance is…found to be unexceptional…”. Ericsson, K.A. (2006). The influence of expertise and deliberate practice on the development of expert performance. In K.A. Ericcson, N. Charness, P.J. Feltovich, & R.R. Hoffman (eds.). The Cambridge Handbook of Expertise and Expert Performance (pp. 683-704). New York: Cambridge University Press.
  • 9. DBT: What do the data say? Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow up of DBT. Archives of General Psychiatry, 63, 757-766.
  • 10. DBT: What do the data say? Linehan, M. et al (2006) Two-Year Randomized Control Trial and Follow up of DBT. Archives of General Psychiatry, 63, 757-766.
  • 11. Study RCT Comparision Gender Race & Ethnicity Age Drop out rate Participants Group (DBT/other) Linnehan et al. Yes Treatment as usual 100% female Not reported 18-45 4/24 (16.7%) v. 6/12 24/24 1991 (Dosing not (50%) BPD reported) 1 Suicide Linnehan et al. Yes Treatment as usual 100% Female Not reported 18-45 3/13 (23%) 13/13 1994 (Dosing not Mean = 26 1 suicide v. 0 BPD reported) Linnehan et al. Yes Treatment as usual 100% female 78% White 18-45 5/12 (41.6%) 12/16 1999 (significantly lower 11% Unspecified Mean = 30 1 death v. 0 BDP/Drug dose) 7% Black D.O. in TAU dropped DBT received 2X 4% Hispanic out prior to treatment as much therapy Linnehan et al. Yes DBT plus 12 steps 100% female 87% White 28-43 4/11 (36%) v. 0/12 11/12 2002 12% Unspecified Mean = 36 BPD/Drug Koons et al. 2001 Yes Treatment as usual 100% female 75% White 31-46 3/14 (21%) v. 2/14 14/14 BPD (significantly lower 25% Black (14%) dose) Van den Bosch et Yes Treatment as usual 100% Female Not reported Mean = 37.5 14/31 (45%) v. 20/27 31/27 al 2002 (significantly lower (74%) Verheul et al. 2003 dose) BPD/Drug Telch et al. 2001 Yes Wait list control 100% Female 94% White Mean = 50 4/22 (18%) v. 6/22 22/22 Binge Eating 6% Unspecified (27%) Safer et al. 2001 Yes Wait list control 100% Female 87% White 18-54 2/14 (14%) v. 1/15 (7%) 14/15 Bulimia 13% Unspecified Mean = 34 Lynch et al. 2003 Partial (n Medication v. Meds 85% Female 85% White 66-80 Not reported 17/17 Depression = 4) plus DBT 15% Male 9% Black Mean = 66 (significantly higher 6% Hispanic dose) Linnehan et al. Yes Community 100% Female 86% White 18-45 11.5% v. 28.6% 52/49 2006 nominated experts 3.8% Black Mean = 29 BPD Asian 1.9% Other 5.8% TOTAL 8.5 1 semi- BPD = 100% Female 81.5% White 18-45 25.9 v. 35.6% Allegiance direct Mean = 31.7 BPD = comparison http://www.nrepp.samhsa.gov/programfulldetails.asp?PROGRAM_ID=72 157
  • 12. DBT: What can we conclude? 1. Extremely small and restricted sample (n = 157; 100% female, 81% White); 2. Allegiance effects in 7/9 studies; 3. No real direct comparisons with another bonafide therapy; 4. Inequalities in dose and intensity of services; 5. No control over known confounds and contributors (especially, therapist and alliance effects).
  • 13. What Works in Therapy: Direct Comparisons & Allegiance Effects Direct Comparisons & Allegiance Effects •Meta-analysis of all studies published between 1980-2006 comparing bona fide treatments for children with ADHD, conduct disorder, anxiety, or depression: •No difference in outcome between approaches intended to be therapeutic; •Researcher allegiance accounted for 100% of variance in effects. Miller, S.D., Wampold, B.E., & Varhely, K. (2008). Direct comparisons of treatment modalities for youth disorders: A meta-analysis. Psychotherapy Research, 18(1), 5-14
  • 14. What Works in Therapy: Alliance & Therapist Effects Researchers found SFT superior to TFP in work with borderline-diagnosed clients: •Significant differences in outcome between therapists; •Alliance significant predictor of retention and improvement, independent of outcome; •“In the more semistructured and long- term treatment of Axis II disorders, the development and maintenance of the therapeutic alliance constitutes a central issue of therapy and may constitute a central curing mechanism.” Spinhoven, P. et al. (2007). The therapeutic alliance in schema-focused therapy and transference-focused psychotherapy for borderline personality disorder. Journal of Consulting and Clinical Psychology, 75(1), 104-115.
  • 15. Smoke and Mirrors Real World Applications DBT for “BPD” • In a large CMHC serving SPMI clients: Of 382 eligible by dx, only 25 (6.5%) thought it was for them; 25% of those dropped out before program started; another 25% dropped out…is it worth the cost? Haynes, M. (2006). Real world applications of evidence based practice. Heart and Soul of Change 3. Bar Harbor, ME.
  • 16. DBT: What can we conclude? Doing ~ Better = D.B.T. Therapy