BIL 2009 talk on Personalized Medicine

1. The Promise and
the Peril of
PERSONALIZED MEDICINE
Jonathan Sheffi
jonathansheffi.com/about
Twitter: @sheffi

8. PERSONALIZED
MEDICINE
is about to
CHANGE YOUR
WORLD

9. What is
PERSONALIZED
MEDICINE
?

10. TYLER DURDEN
WAS WRONG

12. What the *%$#
is a biomarker?

13. NCI: “A biological molecule
found in blood, other body
fluids, or tissues that is a
sign of a normal or abnormal
process, or of a condition or
disease. A biomarker may be
used to see how well the body
responds to a treatment for a
disease or condition. Also
called molecular marker and
signature molecule.”

14. NCI: “A biological molecule
found in blood, other body
fluids, or tissues that is a
sign of a normal or abnormal
Information about
process, or of a condition or
disease. A biomarker may be
your body.
used to see how well the body
responds to a treatment for a
disease or condition. Also
called molecular marker and
signature molecule.”

15. Cost of first genome:
~$2,700,000,000

16. Current cost:
~$5,000

17. “Treatment
Response”
vs
“Disease State”

18. IMPROVE
PATIENT OUTCOMES
and
REDUCE
HEALTHCARE COSTS

21. So what can we
ACTUALLY DO?

25. One Day…

29. When is that Day?

30. One large Pharmacy Benefit
Manager
ALREADY STARTED
THIS PROGRAM

31. THE FUTURE IS NOW

40. SO WHAT?

42. Who is the
LARGEST PAYOR
for healthcare
IN AMERICA
?

44. 45%
of US healthcare
costs are paid
for by some level
of government

45. Anyone think that
OUR GOVERNMENT
wouldn’t mind
SAVING MONEY TOO
?

46. What about…

50. G.I.N.A.
Genetic Information
Nondiscrimination Act
(May 2008)

52. No law on
Use of your genetic information by
the personal genomics companies

53. No law on
Use of your genetic information by
long-term care or life insurance
companies

57. Thank You!
jonathansheffi.com/about
Twitter: @sheffi
Images used under Creative Commons License