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The Promise and
     the Peril of
PERSONALIZED MEDICINE
       Jonathan Sheffi
  jonathansheffi.com/about
       Twitter: ...
PERSONALIZED
  MEDICINE
    is about to



CHANGE YOUR
  WORLD
What is



PERSONALIZED
  MEDICINE
       ?
TYLER DURDEN
 WAS WRONG
What the *%$#
is a biomarker?
NCI: “A biological molecule
  found in blood, other body
 fluids, or tissues that is a
sign of a normal or abnormal
proces...
NCI: “A biological molecule
  found in blood, other body
 fluids, or tissues that is a
sign of a normal or abnormal
Inform...
Cost of first genome:
 ~$2,700,000,000
Current cost:
  ~$5,000
“Treatment
   Response”
       vs
“Disease State”
IMPROVE
PATIENT OUTCOMES
       and


     REDUCE
HEALTHCARE COSTS
So what can we


ACTUALLY DO?
One Day…
When is that Day?
One large Pharmacy Benefit
           Manager



ALREADY STARTED
 THIS PROGRAM
THE FUTURE IS NOW
SO WHAT?
Who is the


LARGEST PAYOR
   for healthcare



 IN AMERICA
         ?
45%


of US healthcare
  costs are paid
for by some level
 of government
Anyone think that


OUR GOVERNMENT
     wouldn’t mind



SAVING MONEY TOO
            ?
What about…
G.I.N.A.
 Genetic Information
Nondiscrimination Act

     (May 2008)
No law on
Use of your genetic information by
the personal genomics companies
No law on
Use of your genetic information by
 long-term care or life insurance
            companies
Thank You!
jonathansheffi.com/about
     Twitter: @sheffi


  Images used under Creative Commons License
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
BIL 2009 Personalized Medicine And Personal Genomics
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BIL 2009 Personalized Medicine And Personal Genomics

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BIL 2009 talk on Personalized Medicine

Published in: Health & Medicine
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BIL 2009 Personalized Medicine And Personal Genomics

  1. 1. The Promise and the Peril of PERSONALIZED MEDICINE Jonathan Sheffi jonathansheffi.com/about Twitter: @sheffi
  2. 2. PERSONALIZED MEDICINE is about to CHANGE YOUR WORLD
  3. 3. What is PERSONALIZED MEDICINE ?
  4. 4. TYLER DURDEN WAS WRONG
  5. 5. What the *%$# is a biomarker?
  6. 6. NCI: “A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.”
  7. 7. NCI: “A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal Information about process, or of a condition or disease. A biomarker may be your body. used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.”
  8. 8. Cost of first genome: ~$2,700,000,000
  9. 9. Current cost: ~$5,000
  10. 10. “Treatment Response” vs “Disease State”
  11. 11. IMPROVE PATIENT OUTCOMES and REDUCE HEALTHCARE COSTS
  12. 12. So what can we ACTUALLY DO?
  13. 13. One Day…
  14. 14. When is that Day?
  15. 15. One large Pharmacy Benefit Manager ALREADY STARTED THIS PROGRAM
  16. 16. THE FUTURE IS NOW
  17. 17. SO WHAT?
  18. 18. Who is the LARGEST PAYOR for healthcare IN AMERICA ?
  19. 19. 45% of US healthcare costs are paid for by some level of government
  20. 20. Anyone think that OUR GOVERNMENT wouldn’t mind SAVING MONEY TOO ?
  21. 21. What about…
  22. 22. G.I.N.A. Genetic Information Nondiscrimination Act (May 2008)
  23. 23. No law on Use of your genetic information by the personal genomics companies
  24. 24. No law on Use of your genetic information by long-term care or life insurance companies
  25. 25. Thank You! jonathansheffi.com/about Twitter: @sheffi Images used under Creative Commons License

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