SlideShare a Scribd company logo
1 of 36
Approach to Joint pain
Dr Manoj Khadka
FCPS resident
• Stepwise history
• Physical examinatioin
• Lab investigations
Step - 1
Articular and Extra-articular
Anatomic structure:
Painful site:
Painful site:
Pain on movement:
Swelling
Crepitus
Diffuse,
deep tenderness
Point tenderness
Active and
passive
Active only
Common
Uncommon
Step - 2
Arthralgia or Arthritis
• Arthralgia-SYMPTOM
• Joint pain withouts obvious
inflammation
• Non specific
• Non rheumatological
conditions like
haematoligical diseases’
post viral fever’
hypothyroidism, statins use
• Arthritis-DIAGNOSIS
• demonstrable features of
joint inflammation(joint
swelling, redness, joint
tenderness)
• Increased temperature
• Rheumatological conditions
like RA, SLE
Step - 3
Arthritis
Inflammatory or Non-inflammatory
Recognizing inflammation in the Joint
History (80% diagnostic)
• Significant early morning stiffness IMPROVING with activity
• Constitutional symptoms (weight loss and loss of appetite)
• Low grade Fever and night sweats
• Fatigue
Examination (15% diagnostic)
• Inflammed Joint(erythematous and indurated appearance)
Lab (5% diagnostic)
• High ESR, CRP, Platelet
• NN anemia
NOT specific for inflammation
• Hard bony swelling
• Tenderness due to
structural damage deformity
• Functional incapitation
Step - 4
Duration
Acute
<6 weeks
Chronic
>6weeks(detailed
Evaluation needed)
Onset of symptoms
Abrupt
(Min-Hrs)
Insidious
(weeks- months)
• RA
• OA
• Trauma
• Crystal Arthropathy
• Infection
Step - 5
How many joints are affected?
Step - 6
Pattern-locationwise
Rheumatoid arthritis Reactive arthritis Ankylosing spondylitis
Psoriatic arthritis Inflammatory OA of Hand
Pattern-sequence wise
Intermittent arthritis
-episodic and patient may be totally asymptomatic in between the episodes
(gout behcets syndrome reactive arthritis palindromic rheumatism
Additive arthritis
-one or more joints are involved with time
(RA SpA Psoriasis OA)
Migratory polyarthritis
-pain and swellinfg in a specific joint starts rapidly and subsides in 24 -36 hrs,arthritis then
Picks up new joints
(rheumatic fever gonococcal arthritis and viral diseases)
Symmetry vs Asymmetry
Step - 7
Step - 8
Extra-articular manifestation
Fever with arthritis
• SLE
• Viral arthritis
• Vasculitis
• Rheumatic Fever
• AOSD
• Brucellosis
Raynaud’s phenomenon
• Scleroderma (commonest)
• SLE
• RA
• Sjogrens
• Myositis
Oral ulcer
Painless
• SLE
• Reactive arthritis
• Enteropathic
Painful
• Bechet
Subcutaneous nodule
• OA
• Rheumatois nodule
• Gout
• Multicentric
reticulohistiocytosis
Arthritis with….
Neuropathy
• SLE
• Vasculitis
• Lyme
• RA
• Amyloidosis
• Cryoglobulinemia
Pulmonary
• AAV(cough,
hemoptysis,
pleuritis)
• SLE (Pleuritis)
• Scleroderma
(ILD,PAH)
• RA (Pleural effussion,
pulmonary nodules,
ILD)
Arthritis with….
Renal invovement
• SLE
• Vasculitis
• Sjogren
• RA
• Amyloidosis
• Cryoglobulinemia
GI involvement
• SLE (intestinal
vasculitis)
• Scleroderma (GERD,
diarrhea, pseudo-
obstruction)
• Enteropathic (IBD)
• PAN (Mesenteric
vasculitis)
Ocular
Keratoconjunctivitis sicca
• Sjogren syndrome, RA, SLE
Uveitis
• SpA, Sarcoidosis, Bechet’s, GPA
Scleritis
• RA, SLE
Family History
• RA
• OA
• AS
• Gout
• Psoriasis
Drug History
• Drug induced lupus: Hydralazine, ACE-inhibitor
• Arthralgia: Quinolones
• Gout: Diurestics
• Vasculitis: Allopurinol, Thiazides
• Scleroderma: Bleomycin
• Osteonecrosis: Glucocorticoid
History of malignancy
Carcinomatous polyarthritis:
• Solid organ (Breast, colon, ovarian, lung)
• Lymphoproliferative disease
RS3PE (Relapsing seronegative symmetric synovitis with pitting
edema):
• Lymphoma
• Myelodysplastic syndrome
Physical Examination
• Inspection
• Palpation
• Assessment of range of motion
Investigation
• Blood test
1. Hematology: CBC, LFT, RFT
2.Biochemistry: Uric acid, ESR, CRP
3. Immunology: RF, ANA
Joint Aspiration
Arthrocentesis (Synovial Fluid Analysis)
• Indicated when there is warm, red joint with effusion, especially
when there is no history of trauma
• Aspirated synovial fluid should be sent for 3Cs:
1. Cell count
2. Crystals: for Gout and Pseudogout
3. Culture (gram stain): for Septic arthritis
Diagnostic imaging
Indication:
• Bony tenderness
• Inability to bear
weight
• Gross deformity
• Age
Modalities :
• Plain flim
• USG
• CT scan
• MRI
Reference
• Clinical Rheumatology- Springer 2019- Rohini Handa
• Kelly’s Rheumatology
Thank you
Approach to Joint pain_Dr Manoj.pkhanaptx

More Related Content

Similar to Approach to Joint pain_Dr Manoj.pkhanaptx

Polyarthritis (clinical approach)
Polyarthritis (clinical approach)Polyarthritis (clinical approach)
Polyarthritis (clinical approach)ankita0809
 
Orthopaedics notes - Crystal Deposition Disorder
Orthopaedics notes - Crystal Deposition DisorderOrthopaedics notes - Crystal Deposition Disorder
Orthopaedics notes - Crystal Deposition DisorderDarcy Jamih
 
Rheumatoid Arthritis
Rheumatoid ArthritisRheumatoid Arthritis
Rheumatoid Arthritisazamcmc50
 
approach to joint pain in pediatrics and treatment of join painpptx
approach to joint pain in pediatrics and treatment of join painpptxapproach to joint pain in pediatrics and treatment of join painpptx
approach to joint pain in pediatrics and treatment of join painpptxmadhurathore16
 
inflammatoryarthritis-170820154705 (1).pdf
inflammatoryarthritis-170820154705 (1).pdfinflammatoryarthritis-170820154705 (1).pdf
inflammatoryarthritis-170820154705 (1).pdfRohit778715
 
Signs and Symptoms in Rheumatology
Signs and Symptoms in RheumatologySigns and Symptoms in Rheumatology
Signs and Symptoms in Rheumatologyaadenitan1
 
Rheumatology Rapid Review
Rheumatology Rapid ReviewRheumatology Rapid Review
Rheumatology Rapid ReviewSami Ur Rehman
 
When to Suspect Autoimmune or Rheumatic Disease
When to Suspect Autoimmune or Rheumatic DiseaseWhen to Suspect Autoimmune or Rheumatic Disease
When to Suspect Autoimmune or Rheumatic DiseaseSamar Tharwat
 
seronegative spondyloarthropaty.pptx
seronegative spondyloarthropaty.pptxseronegative spondyloarthropaty.pptx
seronegative spondyloarthropaty.pptxKishore Vemula
 
Immune diseases
Immune diseasesImmune diseases
Immune diseasesdream10f
 
Seronegative arthropathies
Seronegative arthropathiesSeronegative arthropathies
Seronegative arthropathiesNirav Prajapati
 

Similar to Approach to Joint pain_Dr Manoj.pkhanaptx (20)

Polyarthritis (clinical approach)
Polyarthritis (clinical approach)Polyarthritis (clinical approach)
Polyarthritis (clinical approach)
 
Orthopaedics notes - Crystal Deposition Disorder
Orthopaedics notes - Crystal Deposition DisorderOrthopaedics notes - Crystal Deposition Disorder
Orthopaedics notes - Crystal Deposition Disorder
 
Spondylarthropathy
SpondylarthropathySpondylarthropathy
Spondylarthropathy
 
Approach to musculoskeletal pain ahmed yehia Ismaeel, MD
Approach to musculoskeletal pain ahmed yehia Ismaeel, MDApproach to musculoskeletal pain ahmed yehia Ismaeel, MD
Approach to musculoskeletal pain ahmed yehia Ismaeel, MD
 
Rheumatoid Arthritis
Rheumatoid ArthritisRheumatoid Arthritis
Rheumatoid Arthritis
 
Arthritis
ArthritisArthritis
Arthritis
 
approach to joint pain in pediatrics and treatment of join painpptx
approach to joint pain in pediatrics and treatment of join painpptxapproach to joint pain in pediatrics and treatment of join painpptx
approach to joint pain in pediatrics and treatment of join painpptx
 
inflammatoryarthritis-170820154705 (1).pdf
inflammatoryarthritis-170820154705 (1).pdfinflammatoryarthritis-170820154705 (1).pdf
inflammatoryarthritis-170820154705 (1).pdf
 
Signs and Symptoms in Rheumatology
Signs and Symptoms in RheumatologySigns and Symptoms in Rheumatology
Signs and Symptoms in Rheumatology
 
Inflammatory arthritis
Inflammatory arthritisInflammatory arthritis
Inflammatory arthritis
 
Holistic Approach to rheumatic patients Ahmed Yehia Ismaeel, Lecturer of inte...
Holistic Approach to rheumatic patients Ahmed Yehia Ismaeel, Lecturer of inte...Holistic Approach to rheumatic patients Ahmed Yehia Ismaeel, Lecturer of inte...
Holistic Approach to rheumatic patients Ahmed Yehia Ismaeel, Lecturer of inte...
 
Rheumatology Rapid Review
Rheumatology Rapid ReviewRheumatology Rapid Review
Rheumatology Rapid Review
 
Arthritis1
Arthritis1Arthritis1
Arthritis1
 
RHEUMATOLOGY(2).pptx
RHEUMATOLOGY(2).pptxRHEUMATOLOGY(2).pptx
RHEUMATOLOGY(2).pptx
 
Diabetic foot.pptx
Diabetic foot.pptxDiabetic foot.pptx
Diabetic foot.pptx
 
When to Suspect Autoimmune or Rheumatic Disease
When to Suspect Autoimmune or Rheumatic DiseaseWhen to Suspect Autoimmune or Rheumatic Disease
When to Suspect Autoimmune or Rheumatic Disease
 
seronegative spondyloarthropaty.pptx
seronegative spondyloarthropaty.pptxseronegative spondyloarthropaty.pptx
seronegative spondyloarthropaty.pptx
 
Immune diseases
Immune diseasesImmune diseases
Immune diseases
 
Seronegative arthropathies
Seronegative arthropathiesSeronegative arthropathies
Seronegative arthropathies
 
Clinical approach to Arthritis
Clinical approach to ArthritisClinical approach to Arthritis
Clinical approach to Arthritis
 

More from RAMJIBANYADAV2

b38fb7b2-a49e-4088-956a-9ec3ed283225.pptx
b38fb7b2-a49e-4088-956a-9ec3ed283225.pptxb38fb7b2-a49e-4088-956a-9ec3ed283225.pptx
b38fb7b2-a49e-4088-956a-9ec3ed283225.pptxRAMJIBANYADAV2
 
GA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPI
GA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPIGA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPI
GA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPIRAMJIBANYADAV2
 
tubercolosis drugs.pptx ram jiban yaadav
tubercolosis drugs.pptx ram jiban yaadavtubercolosis drugs.pptx ram jiban yaadav
tubercolosis drugs.pptx ram jiban yaadavRAMJIBANYADAV2
 
tuberculosis ram. nepal civil service hosp
tuberculosis ram. nepal civil service hosptuberculosis ram. nepal civil service hosp
tuberculosis ram. nepal civil service hospRAMJIBANYADAV2
 
feverofunknownorigin-200601052555.pptx ppt
feverofunknownorigin-200601052555.pptx pptfeverofunknownorigin-200601052555.pptx ppt
feverofunknownorigin-200601052555.pptx pptRAMJIBANYADAV2
 
feverofunkownorigin-190121090327.pdf ram
feverofunkownorigin-190121090327.pdf ramfeverofunkownorigin-190121090327.pdf ram
feverofunkownorigin-190121090327.pdf ramRAMJIBANYADAV2
 
1663503021.ppt ram jiban Yadav heath b dsa
1663503021.ppt ram jiban Yadav heath b dsa1663503021.ppt ram jiban Yadav heath b dsa
1663503021.ppt ram jiban Yadav heath b dsaRAMJIBANYADAV2
 
DOC-20240314-WA0000..pptx Nyssa nuts hugj
DOC-20240314-WA0000..pptx Nyssa nuts hugjDOC-20240314-WA0000..pptx Nyssa nuts hugj
DOC-20240314-WA0000..pptx Nyssa nuts hugjRAMJIBANYADAV2
 
ram%20jivan%20ppt%20new-1.pptx civil Nepal
ram%20jivan%20ppt%20new-1.pptx civil Nepalram%20jivan%20ppt%20new-1.pptx civil Nepal
ram%20jivan%20ppt%20new-1.pptx civil NepalRAMJIBANYADAV2
 
HYPOCALCEMIA.pptx ram jiban yadav civil nepa
HYPOCALCEMIA.pptx ram jiban yadav civil nepaHYPOCALCEMIA.pptx ram jiban yadav civil nepa
HYPOCALCEMIA.pptx ram jiban yadav civil nepaRAMJIBANYADAV2
 
Presentation1.pptxram jiban yadav civil ne
Presentation1.pptxram jiban yadav civil nePresentation1.pptxram jiban yadav civil ne
Presentation1.pptxram jiban yadav civil neRAMJIBANYADAV2
 
DR.RAM%20PPT.pptxcivil service Nepal kathM
DR.RAM%20PPT.pptxcivil service Nepal kathMDR.RAM%20PPT.pptxcivil service Nepal kathM
DR.RAM%20PPT.pptxcivil service Nepal kathMRAMJIBANYADAV2
 
DENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPAL
DENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPALDENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPAL
DENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPALRAMJIBANYADAV2
 
scrub typhus.pptx dr.ramjiban yadav nepal
scrub typhus.pptx dr.ramjiban yadav nepalscrub typhus.pptx dr.ramjiban yadav nepal
scrub typhus.pptx dr.ramjiban yadav nepalRAMJIBANYADAV2
 
rheumatoid arthritis.pptx dr.ramjibanyadav
rheumatoid arthritis.pptx dr.ramjibanyadavrheumatoid arthritis.pptx dr.ramjibanyadav
rheumatoid arthritis.pptx dr.ramjibanyadavRAMJIBANYADAV2
 
SLE TX.pptx dr.riffat anasari civil hospital
SLE TX.pptx dr.riffat anasari civil hospitalSLE TX.pptx dr.riffat anasari civil hospital
SLE TX.pptx dr.riffat anasari civil hospitalRAMJIBANYADAV2
 
Vertigo.pptx dr. riffar ansari civil hospital
Vertigo.pptx dr. riffar ansari civil hospitalVertigo.pptx dr. riffar ansari civil hospital
Vertigo.pptx dr. riffar ansari civil hospitalRAMJIBANYADAV2
 
Hypocalcemia-PPT dr.ram jiban yadav nepal civil service hospital
Hypocalcemia-PPT dr.ram jiban yadav nepal civil service hospitalHypocalcemia-PPT dr.ram jiban yadav nepal civil service hospital
Hypocalcemia-PPT dr.ram jiban yadav nepal civil service hospitalRAMJIBANYADAV2
 

More from RAMJIBANYADAV2 (18)

b38fb7b2-a49e-4088-956a-9ec3ed283225.pptx
b38fb7b2-a49e-4088-956a-9ec3ed283225.pptxb38fb7b2-a49e-4088-956a-9ec3ed283225.pptx
b38fb7b2-a49e-4088-956a-9ec3ed283225.pptx
 
GA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPI
GA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPIGA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPI
GA_LECTURE.pptDR.RAM JIBAN YADAV CIVIL HOSPI
 
tubercolosis drugs.pptx ram jiban yaadav
tubercolosis drugs.pptx ram jiban yaadavtubercolosis drugs.pptx ram jiban yaadav
tubercolosis drugs.pptx ram jiban yaadav
 
tuberculosis ram. nepal civil service hosp
tuberculosis ram. nepal civil service hosptuberculosis ram. nepal civil service hosp
tuberculosis ram. nepal civil service hosp
 
feverofunknownorigin-200601052555.pptx ppt
feverofunknownorigin-200601052555.pptx pptfeverofunknownorigin-200601052555.pptx ppt
feverofunknownorigin-200601052555.pptx ppt
 
feverofunkownorigin-190121090327.pdf ram
feverofunkownorigin-190121090327.pdf ramfeverofunkownorigin-190121090327.pdf ram
feverofunkownorigin-190121090327.pdf ram
 
1663503021.ppt ram jiban Yadav heath b dsa
1663503021.ppt ram jiban Yadav heath b dsa1663503021.ppt ram jiban Yadav heath b dsa
1663503021.ppt ram jiban Yadav heath b dsa
 
DOC-20240314-WA0000..pptx Nyssa nuts hugj
DOC-20240314-WA0000..pptx Nyssa nuts hugjDOC-20240314-WA0000..pptx Nyssa nuts hugj
DOC-20240314-WA0000..pptx Nyssa nuts hugj
 
ram%20jivan%20ppt%20new-1.pptx civil Nepal
ram%20jivan%20ppt%20new-1.pptx civil Nepalram%20jivan%20ppt%20new-1.pptx civil Nepal
ram%20jivan%20ppt%20new-1.pptx civil Nepal
 
HYPOCALCEMIA.pptx ram jiban yadav civil nepa
HYPOCALCEMIA.pptx ram jiban yadav civil nepaHYPOCALCEMIA.pptx ram jiban yadav civil nepa
HYPOCALCEMIA.pptx ram jiban yadav civil nepa
 
Presentation1.pptxram jiban yadav civil ne
Presentation1.pptxram jiban yadav civil nePresentation1.pptxram jiban yadav civil ne
Presentation1.pptxram jiban yadav civil ne
 
DR.RAM%20PPT.pptxcivil service Nepal kathM
DR.RAM%20PPT.pptxcivil service Nepal kathMDR.RAM%20PPT.pptxcivil service Nepal kathM
DR.RAM%20PPT.pptxcivil service Nepal kathM
 
DENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPAL
DENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPALDENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPAL
DENGUE FEVER BY DR.RADHE.pptx CIVIL HOSPITAL NEPAL
 
scrub typhus.pptx dr.ramjiban yadav nepal
scrub typhus.pptx dr.ramjiban yadav nepalscrub typhus.pptx dr.ramjiban yadav nepal
scrub typhus.pptx dr.ramjiban yadav nepal
 
rheumatoid arthritis.pptx dr.ramjibanyadav
rheumatoid arthritis.pptx dr.ramjibanyadavrheumatoid arthritis.pptx dr.ramjibanyadav
rheumatoid arthritis.pptx dr.ramjibanyadav
 
SLE TX.pptx dr.riffat anasari civil hospital
SLE TX.pptx dr.riffat anasari civil hospitalSLE TX.pptx dr.riffat anasari civil hospital
SLE TX.pptx dr.riffat anasari civil hospital
 
Vertigo.pptx dr. riffar ansari civil hospital
Vertigo.pptx dr. riffar ansari civil hospitalVertigo.pptx dr. riffar ansari civil hospital
Vertigo.pptx dr. riffar ansari civil hospital
 
Hypocalcemia-PPT dr.ram jiban yadav nepal civil service hospital
Hypocalcemia-PPT dr.ram jiban yadav nepal civil service hospitalHypocalcemia-PPT dr.ram jiban yadav nepal civil service hospital
Hypocalcemia-PPT dr.ram jiban yadav nepal civil service hospital
 

Recently uploaded

Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...Taniya Sharma
 
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore EscortsCall Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escortsvidya singh
 
Russian Escorts Girls Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls Delhi
Russian Escorts Girls  Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls DelhiRussian Escorts Girls  Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls Delhi
Russian Escorts Girls Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls DelhiAlinaDevecerski
 
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...chandars293
 
Top Rated Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...
Top Rated  Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...Top Rated  Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...
Top Rated Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...chandars293
 
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Dipal Arora
 
Russian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls Jaipur
Russian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls JaipurRussian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls Jaipur
Russian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls Jaipurparulsinha
 
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service KochiLow Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service KochiSuhani Kapoor
 
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...narwatsonia7
 
VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...
VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...
VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...Neha Kaur
 
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...jageshsingh5554
 
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...hotbabesbook
 
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...Garima Khatri
 
Lucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel roomLucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel roomdiscovermytutordmt
 
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...narwatsonia7
 
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 

Recently uploaded (20)

Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 9907093804 Top Class Call Girl Service Available
 
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
💎VVIP Kolkata Call Girls Parganas🩱7001035870🩱Independent Girl ( Ac Rooms Avai...
 
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore EscortsCall Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
Call Girls Horamavu WhatsApp Number 7001035870 Meeting With Bangalore Escorts
 
Russian Escorts Girls Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls Delhi
Russian Escorts Girls  Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls DelhiRussian Escorts Girls  Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls Delhi
Russian Escorts Girls Nehru Place ZINATHI 🔝9711199012 ☪ 24/7 Call Girls Delhi
 
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
The Most Attractive Hyderabad Call Girls Kothapet 𖠋 6297143586 𖠋 Will You Mis...
 
Top Rated Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...
Top Rated  Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...Top Rated  Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...
Top Rated Hyderabad Call Girls Erragadda ⟟ 6297143586 ⟟ Call Me For Genuine ...
 
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
 
Russian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls Jaipur
Russian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls JaipurRussian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls Jaipur
Russian Call Girls in Jaipur Riya WhatsApp ❤8445551418 VIP Call Girls Jaipur
 
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service KochiLow Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
Low Rate Call Girls Kochi Anika 8250192130 Independent Escort Service Kochi
 
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
Top Rated Bangalore Call Girls Mg Road ⟟ 8250192130 ⟟ Call Me For Genuine Sex...
 
VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...
VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...
VIP Russian Call Girls in Varanasi Samaira 8250192130 Independent Escort Serv...
 
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Ludhiana Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 9907093804 Top Class Call Girl Service Available
 
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
 
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
 
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
VIP Mumbai Call Girls Hiranandani Gardens Just Call 9920874524 with A/C Room ...
 
Lucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel roomLucknow Call girls - 8800925952 - 24x7 service with hotel room
Lucknow Call girls - 8800925952 - 24x7 service with hotel room
 
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
VIP Call Girls Tirunelveli Aaradhya 8250192130 Independent Escort Service Tir...
 
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 9907093804 Top Class Call Girl Service Available
 

Approach to Joint pain_Dr Manoj.pkhanaptx

  • 1. Approach to Joint pain Dr Manoj Khadka FCPS resident
  • 2.
  • 3.
  • 4.
  • 5. • Stepwise history • Physical examinatioin • Lab investigations
  • 6. Step - 1 Articular and Extra-articular Anatomic structure: Painful site: Painful site: Pain on movement: Swelling Crepitus Diffuse, deep tenderness Point tenderness Active and passive Active only Common Uncommon
  • 7. Step - 2 Arthralgia or Arthritis • Arthralgia-SYMPTOM • Joint pain withouts obvious inflammation • Non specific • Non rheumatological conditions like haematoligical diseases’ post viral fever’ hypothyroidism, statins use • Arthritis-DIAGNOSIS • demonstrable features of joint inflammation(joint swelling, redness, joint tenderness) • Increased temperature • Rheumatological conditions like RA, SLE
  • 8. Step - 3 Arthritis Inflammatory or Non-inflammatory
  • 9. Recognizing inflammation in the Joint History (80% diagnostic) • Significant early morning stiffness IMPROVING with activity • Constitutional symptoms (weight loss and loss of appetite) • Low grade Fever and night sweats • Fatigue Examination (15% diagnostic) • Inflammed Joint(erythematous and indurated appearance) Lab (5% diagnostic) • High ESR, CRP, Platelet • NN anemia NOT specific for inflammation • Hard bony swelling • Tenderness due to structural damage deformity • Functional incapitation
  • 10. Step - 4 Duration Acute <6 weeks Chronic >6weeks(detailed Evaluation needed) Onset of symptoms Abrupt (Min-Hrs) Insidious (weeks- months) • RA • OA • Trauma • Crystal Arthropathy • Infection
  • 11. Step - 5 How many joints are affected?
  • 13. Rheumatoid arthritis Reactive arthritis Ankylosing spondylitis
  • 15. Pattern-sequence wise Intermittent arthritis -episodic and patient may be totally asymptomatic in between the episodes (gout behcets syndrome reactive arthritis palindromic rheumatism Additive arthritis -one or more joints are involved with time (RA SpA Psoriasis OA) Migratory polyarthritis -pain and swellinfg in a specific joint starts rapidly and subsides in 24 -36 hrs,arthritis then Picks up new joints (rheumatic fever gonococcal arthritis and viral diseases)
  • 17. Step - 8 Extra-articular manifestation
  • 18. Fever with arthritis • SLE • Viral arthritis • Vasculitis • Rheumatic Fever • AOSD • Brucellosis
  • 19. Raynaud’s phenomenon • Scleroderma (commonest) • SLE • RA • Sjogrens • Myositis
  • 20. Oral ulcer Painless • SLE • Reactive arthritis • Enteropathic Painful • Bechet
  • 21. Subcutaneous nodule • OA • Rheumatois nodule • Gout • Multicentric reticulohistiocytosis
  • 22. Arthritis with…. Neuropathy • SLE • Vasculitis • Lyme • RA • Amyloidosis • Cryoglobulinemia Pulmonary • AAV(cough, hemoptysis, pleuritis) • SLE (Pleuritis) • Scleroderma (ILD,PAH) • RA (Pleural effussion, pulmonary nodules, ILD)
  • 23. Arthritis with…. Renal invovement • SLE • Vasculitis • Sjogren • RA • Amyloidosis • Cryoglobulinemia GI involvement • SLE (intestinal vasculitis) • Scleroderma (GERD, diarrhea, pseudo- obstruction) • Enteropathic (IBD) • PAN (Mesenteric vasculitis)
  • 24. Ocular Keratoconjunctivitis sicca • Sjogren syndrome, RA, SLE Uveitis • SpA, Sarcoidosis, Bechet’s, GPA Scleritis • RA, SLE
  • 25. Family History • RA • OA • AS • Gout • Psoriasis
  • 26. Drug History • Drug induced lupus: Hydralazine, ACE-inhibitor • Arthralgia: Quinolones • Gout: Diurestics • Vasculitis: Allopurinol, Thiazides • Scleroderma: Bleomycin • Osteonecrosis: Glucocorticoid
  • 27. History of malignancy Carcinomatous polyarthritis: • Solid organ (Breast, colon, ovarian, lung) • Lymphoproliferative disease RS3PE (Relapsing seronegative symmetric synovitis with pitting edema): • Lymphoma • Myelodysplastic syndrome
  • 28. Physical Examination • Inspection • Palpation • Assessment of range of motion
  • 29.
  • 30.
  • 31. Investigation • Blood test 1. Hematology: CBC, LFT, RFT 2.Biochemistry: Uric acid, ESR, CRP 3. Immunology: RF, ANA
  • 32. Joint Aspiration Arthrocentesis (Synovial Fluid Analysis) • Indicated when there is warm, red joint with effusion, especially when there is no history of trauma • Aspirated synovial fluid should be sent for 3Cs: 1. Cell count 2. Crystals: for Gout and Pseudogout 3. Culture (gram stain): for Septic arthritis
  • 33. Diagnostic imaging Indication: • Bony tenderness • Inability to bear weight • Gross deformity • Age Modalities : • Plain flim • USG • CT scan • MRI
  • 34. Reference • Clinical Rheumatology- Springer 2019- Rohini Handa • Kelly’s Rheumatology

Editor's Notes

  1. Before beginning with Joint pain, it is important to know about the MSK pain as it may arise from various tissue other than Joint itself. Paint arising from………
  2. Head to toe examination is very important as this young female presenting with polyarthritis and fever has alopecia, malar rash and ecchymosis in leg as may be due to vasculitis.
  3. These features are very common in Seronegative arthritis
  4. Many rheumatologival disease present with NN anemia, and its important to do other test for drug adjustment