The sermon discusses the importance of worshipping God above all else and offering oneself as a living sacrifice dedicated to pleasing God. It emphasizes that we were created by God for His pleasure and should love God with our mind, heart, soul, and strength in response to His great love and mercy. Worship is about dedicating oneself to God's service, not just activities. The sermon encourages the congregation to give back to God with their love, attention, affection, and ability.