SlideShare a Scribd company logo
1 of 31
LINKAGE AND CROSSING OVER
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mendel's Law of Independent Assortment   Allele pairs separate independently during the formation of gametes. This means that traits are transmitted to offspring independently of one another.
Dihybrid cross - phenotypes
Independent assortment An Interpretation from the Dihybrid cross   ,[object Object],[object Object],[object Object]
Discovery of Linkage ,[object Object]
Bateson and Punnett also studied peas: Flower Color: P = purple p = red Pollen seed shape: L = long l = round True Breeding lines: PPLL   x ppll P PpLl F1 Phenotype Number   Exp Ratio Exp Number Purple long 284 9 215 Purple round 21 3   71 Red long   21 3   71 Red round 55 1   24 What is going on???? Crosses produced a deviation from the predicted  Mendelian independent assortment ratios.
[object Object]
Test cross F1 to double recessive: Parents PpLl  X  ppll Gametes PL pl Pl pL pl Expect 1:1:1:1 ratio of phenotypes Bateson and Punnett observed 7:1:1:7 Some gamete types more common that others…but why???
[object Object],[object Object]
[object Object],[object Object]
MORGAN’S EXPERIMENTS ,[object Object],[object Object],[object Object]
Morgan’s experimental crosses of white-eye and miniature-wing variants of  Drosophila melanogaster ,[object Object],[object Object]
What is Linkage? ,[object Object],[object Object],[object Object],[object Object],[object Object]
Morgan and Crossing Over ,[object Object],[object Object]
Process of Recombination ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Recombination Process
Peter J. Russell,  iGenetics : Copyright © Pearson Education, Inc., publishing as Benjamin Cummings. Mechanism of crossing-over
No Linkage: Independent Assortment
Linkage without Recombination
Linkage with Recombination
Linkage Mapping ,[object Object],[object Object],[object Object],[object Object]
Detecting Linkage through Testcrosses ,[object Object],[object Object],[object Object],[object Object]
Sturtevant and Mapping ,[object Object],[object Object],[object Object],[object Object]
Sturtevant’s Interpretation ,[object Object]
Single Crossovers: Non-crossover (Parental) and Crossover (Recombinant) Gametes What is the maximum % recombination?
Map Units ,[object Object],[object Object],[object Object],[object Object],[object Object]
III. Three-Point Mapping ,[object Object],[object Object],[object Object]
Genetic Map of  Drosophila melanogaster
Interference ,[object Object],[object Object],[object Object]

More Related Content

What's hot (20)

Dihybrid cross
Dihybrid crossDihybrid cross
Dihybrid cross
 
Extra chromosomal inheritance
Extra chromosomal inheritanceExtra chromosomal inheritance
Extra chromosomal inheritance
 
Linkage and crossing over
Linkage and crossing overLinkage and crossing over
Linkage and crossing over
 
Linkage – concept, types and theories
Linkage – concept, types and theoriesLinkage – concept, types and theories
Linkage – concept, types and theories
 
Complementation test
Complementation testComplementation test
Complementation test
 
Cytoplasmic inheritance
Cytoplasmic inheritanceCytoplasmic inheritance
Cytoplasmic inheritance
 
Chromosomal theory of inheritance
Chromosomal theory of inheritanceChromosomal theory of inheritance
Chromosomal theory of inheritance
 
LINKAGE
LINKAGELINKAGE
LINKAGE
 
Chromosome or gene mapping &Linkage analysis
Chromosome or gene mapping &Linkage analysisChromosome or gene mapping &Linkage analysis
Chromosome or gene mapping &Linkage analysis
 
Gene linkage
Gene linkageGene linkage
Gene linkage
 
Lethal allele
Lethal alleleLethal allele
Lethal allele
 
PLEIOTROPY
PLEIOTROPYPLEIOTROPY
PLEIOTROPY
 
Polygenic inheritance
Polygenic inheritancePolygenic inheritance
Polygenic inheritance
 
GENETIC TERMINOLOGY AND MENDELIAN GENETICS
GENETIC TERMINOLOGY AND MENDELIAN GENETICSGENETIC TERMINOLOGY AND MENDELIAN GENETICS
GENETIC TERMINOLOGY AND MENDELIAN GENETICS
 
Genetic linkage and crossing over
Genetic linkage and crossing overGenetic linkage and crossing over
Genetic linkage and crossing over
 
Linkage mapping
Linkage mappingLinkage mapping
Linkage mapping
 
linkage
linkagelinkage
linkage
 
History of genetics
History of geneticsHistory of genetics
History of genetics
 
SEX DETERMINATION (GENETICS)
SEX DETERMINATION (GENETICS)SEX DETERMINATION (GENETICS)
SEX DETERMINATION (GENETICS)
 
Lethal genes and gene therapy
Lethal genes and gene therapyLethal genes and gene therapy
Lethal genes and gene therapy
 

Similar to Linkage and crossing over

Linkageandcrossingover 101216024248-phpapp01
Linkageandcrossingover 101216024248-phpapp01Linkageandcrossingover 101216024248-phpapp01
Linkageandcrossingover 101216024248-phpapp01akhlaq12
 
linkage and recombination.pptx
linkage and recombination.pptxlinkage and recombination.pptx
linkage and recombination.pptxYoGeshSharma834784
 
LINKAGE AND CROSSING OVER
LINKAGE AND CROSSING OVERLINKAGE AND CROSSING OVER
LINKAGE AND CROSSING OVERrocking-angel
 
linkage and crossing over
 linkage and crossing over linkage and crossing over
linkage and crossing overShaliniRoy19
 
Linkage and Crossing over (Sanjay Chetry).pptx
Linkage and Crossing over (Sanjay Chetry).pptxLinkage and Crossing over (Sanjay Chetry).pptx
Linkage and Crossing over (Sanjay Chetry).pptxsanjaychetry2
 
Chapter 3 chromosomal basis of inheritance
Chapter 3 chromosomal basis of inheritanceChapter 3 chromosomal basis of inheritance
Chapter 3 chromosomal basis of inheritanceMosesPackiaraj2
 
AP Biology Ch 12 gene linkage groups and chromosome maps
AP Biology Ch 12 gene linkage groups and chromosome mapsAP Biology Ch 12 gene linkage groups and chromosome maps
AP Biology Ch 12 gene linkage groups and chromosome mapsStephanie Beck
 
Genetics- Chapter 5 - Principles of inheritance and variation.docx
Genetics- Chapter 5 - Principles of inheritance and variation.docxGenetics- Chapter 5 - Principles of inheritance and variation.docx
Genetics- Chapter 5 - Principles of inheritance and variation.docxAjay Kumar Gautam
 
LINKAGE-AND-CROSSING-OVER-8.ppt
LINKAGE-AND-CROSSING-OVER-8.pptLINKAGE-AND-CROSSING-OVER-8.ppt
LINKAGE-AND-CROSSING-OVER-8.pptMAHAZELTEOLOGO3
 
LINKAGE AND CROSSING OVER ppt.pptx
LINKAGE AND CROSSING OVER ppt.pptxLINKAGE AND CROSSING OVER ppt.pptx
LINKAGE AND CROSSING OVER ppt.pptxhajirasheik1
 
Linkage and crossing over.. Dr. krishna
Linkage and crossing over.. Dr. krishnaLinkage and crossing over.. Dr. krishna
Linkage and crossing over.. Dr. krishnaMangalore University
 

Similar to Linkage and crossing over (20)

Linkageandcrossingover 101216024248-phpapp01
Linkageandcrossingover 101216024248-phpapp01Linkageandcrossingover 101216024248-phpapp01
Linkageandcrossingover 101216024248-phpapp01
 
Linkage and crossing over
Linkage and crossing overLinkage and crossing over
Linkage and crossing over
 
2014 plant-meiosis
2014 plant-meiosis2014 plant-meiosis
2014 plant-meiosis
 
linkage and recombination.pptx
linkage and recombination.pptxlinkage and recombination.pptx
linkage and recombination.pptx
 
LINKAGE AND CROSSING OVER
LINKAGE AND CROSSING OVERLINKAGE AND CROSSING OVER
LINKAGE AND CROSSING OVER
 
linkage and crossing over
 linkage and crossing over linkage and crossing over
linkage and crossing over
 
linkage.pptx
linkage.pptxlinkage.pptx
linkage.pptx
 
Linkage-GBR.pdf
Linkage-GBR.pdfLinkage-GBR.pdf
Linkage-GBR.pdf
 
LINKAGE
LINKAGELINKAGE
LINKAGE
 
Linkage and Crossing over (Sanjay Chetry).pptx
Linkage and Crossing over (Sanjay Chetry).pptxLinkage and Crossing over (Sanjay Chetry).pptx
Linkage and Crossing over (Sanjay Chetry).pptx
 
Chapter 3 chromosomal basis of inheritance
Chapter 3 chromosomal basis of inheritanceChapter 3 chromosomal basis of inheritance
Chapter 3 chromosomal basis of inheritance
 
AP Biology Ch 12 gene linkage groups and chromosome maps
AP Biology Ch 12 gene linkage groups and chromosome mapsAP Biology Ch 12 gene linkage groups and chromosome maps
AP Biology Ch 12 gene linkage groups and chromosome maps
 
Linkages 6
Linkages 6Linkages 6
Linkages 6
 
Genetics- Chapter 5 - Principles of inheritance and variation.docx
Genetics- Chapter 5 - Principles of inheritance and variation.docxGenetics- Chapter 5 - Principles of inheritance and variation.docx
Genetics- Chapter 5 - Principles of inheritance and variation.docx
 
Genetic linkage
Genetic linkageGenetic linkage
Genetic linkage
 
Linkage
LinkageLinkage
Linkage
 
LINKAGE-AND-CROSSING-OVER-8.ppt
LINKAGE-AND-CROSSING-OVER-8.pptLINKAGE-AND-CROSSING-OVER-8.ppt
LINKAGE-AND-CROSSING-OVER-8.ppt
 
LINKAGE AND CROSSING OVER ppt.pptx
LINKAGE AND CROSSING OVER ppt.pptxLINKAGE AND CROSSING OVER ppt.pptx
LINKAGE AND CROSSING OVER ppt.pptx
 
Unit 7 Chromosomes And Phenotype
Unit 7 Chromosomes And PhenotypeUnit 7 Chromosomes And Phenotype
Unit 7 Chromosomes And Phenotype
 
Linkage and crossing over.. Dr. krishna
Linkage and crossing over.. Dr. krishnaLinkage and crossing over.. Dr. krishna
Linkage and crossing over.. Dr. krishna
 

More from surendran aduthila (11)

Happy 2011
Happy  2011Happy  2011
Happy 2011
 
Frog anatomy
Frog anatomyFrog anatomy
Frog anatomy
 
Frog Anatomy and morphology
Frog Anatomy and morphologyFrog Anatomy and morphology
Frog Anatomy and morphology
 
Dna replication
Dna replicationDna replication
Dna replication
 
Dna fingerprinting
Dna fingerprintingDna fingerprinting
Dna fingerprinting
 
Polycistronic gene
Polycistronic genePolycistronic gene
Polycistronic gene
 
Human genome project 1
Human genome project 1Human genome project 1
Human genome project 1
 
Environmental Quiz
Environmental QuizEnvironmental Quiz
Environmental Quiz
 
Bio diversity year
Bio diversity year Bio diversity year
Bio diversity year
 
Microbes in human welfare
Microbes in human welfareMicrobes in human welfare
Microbes in human welfare
 
W H A T I S ‘ L I V I N G’
W H A T  I S ‘ L I V I N G’W H A T  I S ‘ L I V I N G’
W H A T I S ‘ L I V I N G’
 

Recently uploaded

Active Learning Strategies (in short ALS).pdf
Active Learning Strategies (in short ALS).pdfActive Learning Strategies (in short ALS).pdf
Active Learning Strategies (in short ALS).pdfPatidar M
 
Sulphonamides, mechanisms and their uses
Sulphonamides, mechanisms and their usesSulphonamides, mechanisms and their uses
Sulphonamides, mechanisms and their usesVijayaLaxmi84
 
ClimART Action | eTwinning Project
ClimART Action    |    eTwinning ProjectClimART Action    |    eTwinning Project
ClimART Action | eTwinning Projectjordimapav
 
Daily Lesson Plan in Mathematics Quarter 4
Daily Lesson Plan in Mathematics Quarter 4Daily Lesson Plan in Mathematics Quarter 4
Daily Lesson Plan in Mathematics Quarter 4JOYLYNSAMANIEGO
 
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITWQ-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITWQuiz Club NITW
 
Grade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptxGrade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptxkarenfajardo43
 
4.16.24 21st Century Movements for Black Lives.pptx
4.16.24 21st Century Movements for Black Lives.pptx4.16.24 21st Century Movements for Black Lives.pptx
4.16.24 21st Century Movements for Black Lives.pptxmary850239
 
How to Manage Buy 3 Get 1 Free in Odoo 17
How to Manage Buy 3 Get 1 Free in Odoo 17How to Manage Buy 3 Get 1 Free in Odoo 17
How to Manage Buy 3 Get 1 Free in Odoo 17Celine George
 
How to Fix XML SyntaxError in Odoo the 17
How to Fix XML SyntaxError in Odoo the 17How to Fix XML SyntaxError in Odoo the 17
How to Fix XML SyntaxError in Odoo the 17Celine George
 
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...Nguyen Thanh Tu Collection
 
4.11.24 Mass Incarceration and the New Jim Crow.pptx
4.11.24 Mass Incarceration and the New Jim Crow.pptx4.11.24 Mass Incarceration and the New Jim Crow.pptx
4.11.24 Mass Incarceration and the New Jim Crow.pptxmary850239
 
Concurrency Control in Database Management system
Concurrency Control in Database Management systemConcurrency Control in Database Management system
Concurrency Control in Database Management systemChristalin Nelson
 
Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17Celine George
 
4.9.24 School Desegregation in Boston.pptx
4.9.24 School Desegregation in Boston.pptx4.9.24 School Desegregation in Boston.pptx
4.9.24 School Desegregation in Boston.pptxmary850239
 
ARTERIAL BLOOD GAS ANALYSIS........pptx
ARTERIAL BLOOD  GAS ANALYSIS........pptxARTERIAL BLOOD  GAS ANALYSIS........pptx
ARTERIAL BLOOD GAS ANALYSIS........pptxAneriPatwari
 
Indexing Structures in Database Management system.pdf
Indexing Structures in Database Management system.pdfIndexing Structures in Database Management system.pdf
Indexing Structures in Database Management system.pdfChristalin Nelson
 
Q4-PPT-Music9_Lesson-1-Romantic-Opera.pptx
Q4-PPT-Music9_Lesson-1-Romantic-Opera.pptxQ4-PPT-Music9_Lesson-1-Romantic-Opera.pptx
Q4-PPT-Music9_Lesson-1-Romantic-Opera.pptxlancelewisportillo
 
DIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptx
DIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptxDIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptx
DIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptxMichelleTuguinay1
 

Recently uploaded (20)

Active Learning Strategies (in short ALS).pdf
Active Learning Strategies (in short ALS).pdfActive Learning Strategies (in short ALS).pdf
Active Learning Strategies (in short ALS).pdf
 
Sulphonamides, mechanisms and their uses
Sulphonamides, mechanisms and their usesSulphonamides, mechanisms and their uses
Sulphonamides, mechanisms and their uses
 
ClimART Action | eTwinning Project
ClimART Action    |    eTwinning ProjectClimART Action    |    eTwinning Project
ClimART Action | eTwinning Project
 
Daily Lesson Plan in Mathematics Quarter 4
Daily Lesson Plan in Mathematics Quarter 4Daily Lesson Plan in Mathematics Quarter 4
Daily Lesson Plan in Mathematics Quarter 4
 
Paradigm shift in nursing research by RS MEHTA
Paradigm shift in nursing research by RS MEHTAParadigm shift in nursing research by RS MEHTA
Paradigm shift in nursing research by RS MEHTA
 
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITWQ-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
Q-Factor HISPOL Quiz-6th April 2024, Quiz Club NITW
 
Grade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptxGrade Three -ELLNA-REVIEWER-ENGLISH.pptx
Grade Three -ELLNA-REVIEWER-ENGLISH.pptx
 
4.16.24 21st Century Movements for Black Lives.pptx
4.16.24 21st Century Movements for Black Lives.pptx4.16.24 21st Century Movements for Black Lives.pptx
4.16.24 21st Century Movements for Black Lives.pptx
 
How to Manage Buy 3 Get 1 Free in Odoo 17
How to Manage Buy 3 Get 1 Free in Odoo 17How to Manage Buy 3 Get 1 Free in Odoo 17
How to Manage Buy 3 Get 1 Free in Odoo 17
 
How to Fix XML SyntaxError in Odoo the 17
How to Fix XML SyntaxError in Odoo the 17How to Fix XML SyntaxError in Odoo the 17
How to Fix XML SyntaxError in Odoo the 17
 
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
31 ĐỀ THI THỬ VÀO LỚP 10 - TIẾNG ANH - FORM MỚI 2025 - 40 CÂU HỎI - BÙI VĂN V...
 
4.11.24 Mass Incarceration and the New Jim Crow.pptx
4.11.24 Mass Incarceration and the New Jim Crow.pptx4.11.24 Mass Incarceration and the New Jim Crow.pptx
4.11.24 Mass Incarceration and the New Jim Crow.pptx
 
Concurrency Control in Database Management system
Concurrency Control in Database Management systemConcurrency Control in Database Management system
Concurrency Control in Database Management system
 
Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17Tree View Decoration Attribute in the Odoo 17
Tree View Decoration Attribute in the Odoo 17
 
4.9.24 School Desegregation in Boston.pptx
4.9.24 School Desegregation in Boston.pptx4.9.24 School Desegregation in Boston.pptx
4.9.24 School Desegregation in Boston.pptx
 
ARTERIAL BLOOD GAS ANALYSIS........pptx
ARTERIAL BLOOD  GAS ANALYSIS........pptxARTERIAL BLOOD  GAS ANALYSIS........pptx
ARTERIAL BLOOD GAS ANALYSIS........pptx
 
INCLUSIVE EDUCATION PRACTICES FOR TEACHERS AND TRAINERS.pptx
INCLUSIVE EDUCATION PRACTICES FOR TEACHERS AND TRAINERS.pptxINCLUSIVE EDUCATION PRACTICES FOR TEACHERS AND TRAINERS.pptx
INCLUSIVE EDUCATION PRACTICES FOR TEACHERS AND TRAINERS.pptx
 
Indexing Structures in Database Management system.pdf
Indexing Structures in Database Management system.pdfIndexing Structures in Database Management system.pdf
Indexing Structures in Database Management system.pdf
 
Q4-PPT-Music9_Lesson-1-Romantic-Opera.pptx
Q4-PPT-Music9_Lesson-1-Romantic-Opera.pptxQ4-PPT-Music9_Lesson-1-Romantic-Opera.pptx
Q4-PPT-Music9_Lesson-1-Romantic-Opera.pptx
 
DIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptx
DIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptxDIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptx
DIFFERENT BASKETRY IN THE PHILIPPINES PPT.pptx
 

Linkage and crossing over

  • 2.
  • 3. Mendel's Law of Independent Assortment Allele pairs separate independently during the formation of gametes. This means that traits are transmitted to offspring independently of one another.
  • 4. Dihybrid cross - phenotypes
  • 5.
  • 6.
  • 7. Bateson and Punnett also studied peas: Flower Color: P = purple p = red Pollen seed shape: L = long l = round True Breeding lines: PPLL x ppll P PpLl F1 Phenotype Number Exp Ratio Exp Number Purple long 284 9 215 Purple round 21 3 71 Red long 21 3 71 Red round 55 1 24 What is going on???? Crosses produced a deviation from the predicted Mendelian independent assortment ratios.
  • 8.
  • 9. Test cross F1 to double recessive: Parents PpLl X ppll Gametes PL pl Pl pL pl Expect 1:1:1:1 ratio of phenotypes Bateson and Punnett observed 7:1:1:7 Some gamete types more common that others…but why???
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 19. Peter J. Russell, iGenetics : Copyright © Pearson Education, Inc., publishing as Benjamin Cummings. Mechanism of crossing-over
  • 23.
  • 24.
  • 25.
  • 26.
  • 27. Single Crossovers: Non-crossover (Parental) and Crossover (Recombinant) Gametes What is the maximum % recombination?
  • 28.
  • 29.
  • 30. Genetic Map of Drosophila melanogaster
  • 31.