3. What is Progesterone?
• Progesterone is an endogenous steroid
hormone involved in menstrual cycle
,pregnancy & embryogenesis of humans and
other species.Formed in
• CORPUS LEUTEUM
• PLACENTA
• TESTES
• ADRENAL CORTEX
4.
5. FUNCTIONS
Hormone appears after ovulation; causes:
• Development of endometrium
• Inc. Glycogen, mucin & fat in lining epithelial
cells, supresses LH
• Stimulates mammary glands(alveolar system)
• Inc. basal temperature( inc. BMR)
• In large doses,causes androgenic effects
• Does not retain Na Cl and water
6. FUNCTIONS
• During pregnancy,it decreases mother’s auto
immune response
• Drop in progesterone levels initiates labor
• Progesterone supports normal development
of neurons,protective effect on damaged
brain tissue(due to inc. estrogen)
• Enhances functions of serotonin receptors in
brain
7. Continued….
• Raises Epidermal growth factor
• Inc. core temperature
• Reduces spasm
• Acts as anti inflammatory agent
• Prevents endometrial cancer
• Normal value: 15 ng/ml before ovulation
8. Low progesterone in women may cause:
• Depression,
• migraines,
• headache
• Weight gain
• Infertility
• Miscarrige
• Polycystic ovary syndrome
• Menstrual problems
9.
10. Progesterone: high
• High levels of progesterone:
• High levels before cycle
• Headaches
• Moodiness
• Pre_menstrual symptoms
11.
12. PROGESTERONE: A
CURE!
• THESE CONDITIONS HAVE KNOWN
RESPONSE TO PROGESTERONE THERAPY:
• AGGRESSION( DUE TO LOW CHOLESTEROL)
• LUPUS ERYTHMATOSUS(PRECURSOR FOR
CORTISONE_ANTI INFLAMMATORY)
• ALLERGIES(INC. CORTISONE)
13. • HYPO & HYPERGLYCEMIA(REGULATES LEVEL)
• COLD HAND & FEET( THINS BLOOD)
• CONSTIPATION( REDUCES WATER
RETENTION)
• CHRONIC FATIGUE( STRESS HORMONES
MADE FROM PROGESTERONE IN ADRENALS)
• DEPRESSION(BALANCES SEROTONIN LEVELS)