RADIOLOGY CONTRAST MEDIA

1. radiology
Contrast media

2. • CONTRAST MEDIA
•
• 1.RADIO CONTRAST MEDIA
• 2.MRI CONTRAST MEDIA
• 3.ULTRASOUND CONTRASTMEDIA
•

3. • ULTRA SOUND CONTRAST MEDIA
•
• THEY AREMICRO BUBBLES INJECTED IV. WHICH WILL PASS THROUGH THE CAPILLARIES AND STAYS
FOR SOME TIME
•
• ONLY AVAILABLE ORAL – SONO RX
• I.V
• LEVOLIST
• SONAVIST
• IMA VIST
• SONAGEN/ECHOGEN
• QUANTISTON/OPTISON
• FILMIX
• OMALEX
• SONAVUE
• BISPHERE
• DEFINITY

4. • MR CONTRAST AGENTS
• 1.PARAMAGNETIC CONTRAST AGENTS
• 2.SUPER PARAMAGNETIC CONTRAST AGENTS
•
• PARAMAGNETIC CONTRAST AGENTS
• GADOLINIUM – NOT CROSS BBB UNLESS DISRUPTED
•
• FOR LIVER – MANGANESE COMPOUNDS
•
• 2.SUPER PARAMAGNETIC CONTRAST AGENTS
• SUPERPARAMAGNETIC IRON OXIDE
• ULTRA SMALL SUPER PARAMAGNETIC IRON OXIDE
•

5. • RADIOCONTRAST MEDIA
•
• IODINATED CONTRAST
• BARIUM CONTRAST
•
• BARIUM CONTRAST
• BARIUM ENEMA – LARGE BOWEL INVESTIGATION
• BARIUM MEAL AND FOLLOW THROUGH – STOMACH AND SMALL INTESTINE STUDY
• BARIUM SWALLOW – ESOPHAGEA
•
•
• FOR TRACHEO- ESOPHAGEAL FISTULA – DIANOSIL(WATER SOLUBLE – NON IONIC AGENT IS USED)
•
• FOR PERFORATION PERITONITIS – GASTROGRAFFIN IS USED
•
•

6. • IODINE CONTRAST AGENTS
•
• LOW OSMOLAR – IONIC/NON-IONIC
• HIGH OSMOLAR – IONIC
• ISO OSMOLAR – NON- IONIC
•
•
• CONTRAST AGENT RATIO = NO. OF IODINE ATOMS/ NO OF PARTICLES IN SOLUTION
•
•
• HIGH OSMOLAR – 3/2
• (IONIC MONOMERS)
•
• ISO OSMOLAR – 6/1
•
• LOW OSMOLAR – 6/2
•
•

7. • ISOOSMOLAR
•
• IOTROLAN
• Iodixanol
•
• LOW OSMOLAR AGENTS
•
• IONIC
• IOXOGLATE
• NON-IONIC
• IOHEXAL
• IOPENTAL
• IOXILAN
•
•
• HIGH OSMOLAR
• AMIDOTRIZOATE
• IOTHALAMATE
• IOXITHALAMATE
•
•
•

8. • IOTROLAN,IODIXANOL(iso osmolar)
IOXOGLATE(low – ionic), AND HIGH OSMOLAR
AGENTS

9. • ADVERSE REACTIONS
•
• RENAL
• NON – RENAL
– ACUTE
• ACUTE NON –RENAL ADVERSE REACTION
• NON – IG E MEDIATED ANAPHYLACTIC REACTION
•
•
• RENAL REACTION
• RENAL FAILURE
• CRITERIA FOR CONTRAST – INDUCED NEPHROPATHY
•
• 25% INCREASE IN SERUM CREATININE FROM BASELINE OR 0.5 mg INCREASE IN
CREATININE
•

10. •
• PREVENTION BY
• 1.ADEQUATE HYDRATION
• 2.USE LOW – OSMOLAR(NON-IONIC)
• 3.DRUGS
• ACETYL CYSTEINE
• PROSTAGLANDIN
• FENLODOPAM(D1 agonist)
• Antihypertensive agent which increase the renal perfusion
•
• THEOPHYLLINE
• MAGNESIUM
•
•

11. •
•
• INVESTIGATION AND DYE USED
• MYELOGRAPHY – IOHEXOL
• IOPAMIDOL
• METIZOMATE
•
• IOHEXOL , IOPAMIDOL – LESS TOXIC
•
• METRIZOMATE – TOXIC
•
•
• ESOPHAGEAL ATRESIA & TEF – DIANOSIL
• BRONCHOGRAPHY – DIANOSIL
•
• SIALOGRAPHY – NEOHYDRIOL
• SAUSAGE LINK – SALIVARY GLAND DUCT STRICTURE
• SIALADENITIS – PRUNING TREE
• BALL IN HAND – TUMOUR AROUND THE SALIVARY GLAND
•
• URETHROGRAPHY – UMBRADIL VISCOUS V
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• ANGIOGRAPHY – UROGRAFFIN
•
• IVP – SODIUM DIATRIZOATE
•

12. • INTESTINAL OBSTRUCTION – GASTROGRAFFIN
•
•
• SPLENOPORTOGRAPHY – SODIUM METRIZOATE
•
• FETOGRAPHY – ETHIODOL
•
• HYSTEROSALPINGOGRAPHY
• 50 % DIODEN WITH 6% POLYVINYL ALCOHOL IN
WATER