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Tong Pei-Yein, Rachel Law, Lim Hai Fon, Ang ML, Tham HL, Jasmyn A,
Sim J, Chen ZY, Rajaratnam V
Stroke-Hand Surgery
Service
ā€¢ Outpatient-based
ā€¢ Multidisciplinary team
ā€¢ For the management of post-stroke
spasticity, in the upper and lower limbs
Post-stroke Spasticity
ā€¢ 67,289 episodes of stroke were
admitted to public hospitals in the
period 2005-20151: >6000/year
ā€¢ Largest cause of long-term
physical disability2
ā€¢ Prevalence of spasticity : 33-50% 3
ā€¢ Lower functional ability at 12
months
3
1. Singapore Stroke Registry Annual Report 2015
2. Singapore National Stroke Association
3. Kong et al: Occurrence and Temporal Evolution of Upper Limb
Spasticity in Stroke Patients Admitted to a Rehabilitation Unit. Arch Phys
Med Rehabil 2012 Jan;93(1):143-8
Pathophysiology
Li S and Francisco GE (2015) New insights into the
pathophysiology of post-stroke spasticity. Front. Hum.
Neurosci. 9:192
A motor disorder characterized by a
Velocity-dependent,
Increase in tonic stretch reflexes
With exaggerated tendon jerks
Resulting from hyperexcitability of
the stretch reflex
Problems with
spasticity
ā€¢ Pain
ā€¢ Fatigue, inconvenient
involuntary motion
ā€¢ Functional limitations
ā€¢ Contractures
ā€¢ Skin maceration
ā€¢ Poor self image
Traditionally..
Patient
Neurologist
Rehab
physician +
Therapists
Surgeon
Multidisciplinary team
approach required
Need for an integrated care
pathway for these patients
Neurologist
Surgeon
Specialty
nurse
Rehab
physician +
therapists
Design and Development Model
Design
Identify the problem
Recruit expert panel
Design solutions
Develop
Prototype
Gather consensus
Review and redesign
Validate
Pilot
Review
Roll out
8
Spasticity care pathway
Referral sources: Post inpatient discharge, Outpatient Stroke-Hand clinic
General spasticity Regional and focal spasticity
Oral agents
Therapist: Exercises and Splints Determine Contracture Versus Spasticity
SpasticityContracture
ā— Lengthening
procedures
ā— FDS to FDP transfer
ā— Osteotomy
ā— Arthrodesis
Patient has volitional
control?
No
ā— Observe
ā— Prevent
contracture
Botox injectionYes
Improvement
seen
ā— Hyperselective
neurectomy
ā— Tendon transfer
No improvement
ā— Observe
ā— Repeat Botox
ā— Contracture
release
Aims:
Improve function, reduce pain, improve posture/ care
Treatment objectives
a. Reduce tone
b. Improve range of motion
b. Improve joint position
c. Select cases for neurectomy
Improve Function
1. Reduce spasm
frequency
2. Pain relief
3. Improve gait,
ADLs, hygiene,
ease of care
For the patient and
caregiver
1. Improve
appearance
2. Improve self-
confidence
3. Improve
independence
Referral Criteria
Spasticity in upper / lower limb from
ā€¢ Cerebrovascular accidents
ā€¢ Brain / Spinal cord injury
ā€¢ Traumatic
ā€¢ Atraumatic
ā€¢ Neurodegenerative disorders
ā€¢ Multiple sclerosis
ā€¢ Amyotrophic lateral sclerosis
Medically stable to undergo an elective
procedure in an outpatient setting
Patient selection
Inclusion criteria
ā€¢ Hemiplegia or monoplegia
ā€¢ Has good prognosis for recovery
ā€¢ Functionally good ( some volition/Botox
trial/House)
Exclusion criteria
ā€¢ Bedbound patients (except for hygiene and
nursing purposes)
Evaluation
ā€¢ General examination
ā€¢ Evaluation tools
ā€¢ Assessment
scales
ā€¢ Investigations
ā€¢ Botox Trial
ā€¢ Expectations
ā€¢ ?Radiographs
ā€¢ ?Dynamic EMG
ā€¢ ?Nerve blocksGreenā€™s Operative Hand Surgery
7th Edition
Botulinum Toxin-Type A
To FDS muscle
Non-surgical
1. Tone reduction
modalities
a. Medications: muscle relaxants
such as baclofen,
benzodiazepines
b. Injections: Botox
2. Physical Therapy
a. Stretching
b. Adaptive strategies and devices
c. Incorporation of spastic limb in
ADLs
d. Post-op: immobilization,
mobilization, incorporation
3. Orthoses
Surgical
1. Tendon/ muscle
procedures
a. Muscle/tendon lengthening
i. Fractional lengthening
ii. Z lengthening
iii. Muscle slide
b. Tendon transfers
2. Joint/Bone procedures
a. Arthrodesis
b. Osteotomy
3. Nerve procedures
a. Neurectomy
4. Amputations
- Reduce spasticity in target muscles
Technique:
ā€¢ Follows motor ramus until entry point into
target muscle
Improves
ā€¢ Selectivity
ā€¢ Widespread partial denervation
ā€¢ Durability of results
ā€¢ Systematic review: 7 studies, 174
patients
ā€¢ Percentage of fascicles ablated
between 30-80%
ā€¢ Length of neurectomy: 5-10mm
ā€¢ Remove end branches vs fascicular
selective neurectomy proximally
ā€¢ All had improvement in spasticity
ā€¢ Recurrence rate: 0-16.1%
17 Stroke
6 received Botox
3
underwent
HSN
1 underwent
tendon
lengthening
22 patients
3 Focal dystonia2 CP
ā€¢ 12 Male, 5 Female
ā€¢ Mean age 62.9 years
ā€¢ Reviewed average 9months
post-stroke
2 received Botox
1
underwent
HSN
1 received Botox
1
underwent
HSN
Hyperselective Neurectomy (HSN)
Upper limb
1. Biceps 1
2. FCU 1
3. FCR 1
4. FDS 4
5. FPL 2
6. PT 2
Lower limb
1. FDL 2
2. FHL 2
3. Gastrocnemius 1
Biceps Neurectomy
FCU Neurectomy
FCR Neurectomy
FCR branch
Median
nerve
AIN
FDS Neurectomy
Nerve stimulation for identification of
FDS fascicles
ā€¢ Interfascicular dissection
ā€¢ Select branches for neurectomy
(nerve stimulation)
ā€¢ Neurectomy (1-2cm): 2 out of 3
branches
FPL
Right LL:
ā€¢ FDL, FHL spasm
ā€¢ Severe spasm on certain days
ā€¢ Causes clawing of toes and pain
ā€¢ Coping with gait fairly well with orthosis
ā€¢ FHL and FDL spasticity when he walks
FHL
Flexor
Digitorum
Longus
Patient Procedure performed Pre-
surgery
MAS
Post-surgery
MAS
1 HSN Biceps 3 Biceps 1
2 HSN FDS 3
FPL 2
PT 3
FDL 3
FHL 3
FDS 2
FPL 1
PT 2
FDL 1
FHL 1
3 HSN
Tenotomy
ā€¢ Abductor hallucis
FDS 3
FPL 3
FHL 3
FDL 3
FDS 2
FPL 1
FHL 1
FDL 1
4
(Lengthening)
Z-lengthening
Fractional
FPL 3
FDS 4
FPL 0
FDS 3
0
0.5
1
1.5
2
2.5
3
3.5
Pre Post
Average Modified
Ashworth Scale
Average MAS
56% improvement in
spasticity score
Patient Procedure performed Hand
Function
(House)
Pre/Post
Patient
satisfaction
(Good/Fair/Poor)
1 HSN biceps 8/8 Good
2 HSN FDS, FPL, PT
FDL, FHL
2/2 Poor (UL)
Good (LL)
3 HSN FDS, FPL, FHL,
FDL
Tenotomy
ā€¢ Abductor hallucis
1/1 Fair (UL)
Good (LL)
4
(Lengthening)
Z-lengthening
Fractional
8/8 Poor
Conclusions
ā€¢ Evolving management strategies
ā€¢ Simpler assessment instruments
ā€¢ Robust patient experience outcome measures
ā€¢ More interactions among stroke MDT
ā€¢ *Counselling
ā€¢ *Education & raise awareness (patients and
physicians)
Welcome to Singapore for the 2023 APFSSH & APFSHT meeting!
www.apfssh2023.org
Proposed dates:
17-20 May 2023 (Wed to Saturday) OR
24-27 May 2023 (Wed to Saturday)

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Spaticity s troke hand clinic nov 2019

  • 1. Tong Pei-Yein, Rachel Law, Lim Hai Fon, Ang ML, Tham HL, Jasmyn A, Sim J, Chen ZY, Rajaratnam V
  • 2. Stroke-Hand Surgery Service ā€¢ Outpatient-based ā€¢ Multidisciplinary team ā€¢ For the management of post-stroke spasticity, in the upper and lower limbs
  • 3. Post-stroke Spasticity ā€¢ 67,289 episodes of stroke were admitted to public hospitals in the period 2005-20151: >6000/year ā€¢ Largest cause of long-term physical disability2 ā€¢ Prevalence of spasticity : 33-50% 3 ā€¢ Lower functional ability at 12 months 3 1. Singapore Stroke Registry Annual Report 2015 2. Singapore National Stroke Association 3. Kong et al: Occurrence and Temporal Evolution of Upper Limb Spasticity in Stroke Patients Admitted to a Rehabilitation Unit. Arch Phys Med Rehabil 2012 Jan;93(1):143-8
  • 4. Pathophysiology Li S and Francisco GE (2015) New insights into the pathophysiology of post-stroke spasticity. Front. Hum. Neurosci. 9:192 A motor disorder characterized by a Velocity-dependent, Increase in tonic stretch reflexes With exaggerated tendon jerks Resulting from hyperexcitability of the stretch reflex
  • 5. Problems with spasticity ā€¢ Pain ā€¢ Fatigue, inconvenient involuntary motion ā€¢ Functional limitations ā€¢ Contractures ā€¢ Skin maceration ā€¢ Poor self image
  • 7. Multidisciplinary team approach required Need for an integrated care pathway for these patients Neurologist Surgeon Specialty nurse Rehab physician + therapists
  • 8. Design and Development Model Design Identify the problem Recruit expert panel Design solutions Develop Prototype Gather consensus Review and redesign Validate Pilot Review Roll out 8
  • 9. Spasticity care pathway Referral sources: Post inpatient discharge, Outpatient Stroke-Hand clinic General spasticity Regional and focal spasticity Oral agents Therapist: Exercises and Splints Determine Contracture Versus Spasticity SpasticityContracture ā— Lengthening procedures ā— FDS to FDP transfer ā— Osteotomy ā— Arthrodesis Patient has volitional control? No ā— Observe ā— Prevent contracture Botox injectionYes Improvement seen ā— Hyperselective neurectomy ā— Tendon transfer No improvement ā— Observe ā— Repeat Botox ā— Contracture release
  • 10. Aims: Improve function, reduce pain, improve posture/ care Treatment objectives a. Reduce tone b. Improve range of motion b. Improve joint position c. Select cases for neurectomy Improve Function 1. Reduce spasm frequency 2. Pain relief 3. Improve gait, ADLs, hygiene, ease of care For the patient and caregiver 1. Improve appearance 2. Improve self- confidence 3. Improve independence
  • 11. Referral Criteria Spasticity in upper / lower limb from ā€¢ Cerebrovascular accidents ā€¢ Brain / Spinal cord injury ā€¢ Traumatic ā€¢ Atraumatic ā€¢ Neurodegenerative disorders ā€¢ Multiple sclerosis ā€¢ Amyotrophic lateral sclerosis Medically stable to undergo an elective procedure in an outpatient setting
  • 12. Patient selection Inclusion criteria ā€¢ Hemiplegia or monoplegia ā€¢ Has good prognosis for recovery ā€¢ Functionally good ( some volition/Botox trial/House) Exclusion criteria ā€¢ Bedbound patients (except for hygiene and nursing purposes)
  • 13. Evaluation ā€¢ General examination ā€¢ Evaluation tools ā€¢ Assessment scales ā€¢ Investigations ā€¢ Botox Trial ā€¢ Expectations ā€¢ ?Radiographs ā€¢ ?Dynamic EMG ā€¢ ?Nerve blocksGreenā€™s Operative Hand Surgery 7th Edition
  • 15. Non-surgical 1. Tone reduction modalities a. Medications: muscle relaxants such as baclofen, benzodiazepines b. Injections: Botox 2. Physical Therapy a. Stretching b. Adaptive strategies and devices c. Incorporation of spastic limb in ADLs d. Post-op: immobilization, mobilization, incorporation 3. Orthoses Surgical 1. Tendon/ muscle procedures a. Muscle/tendon lengthening i. Fractional lengthening ii. Z lengthening iii. Muscle slide b. Tendon transfers 2. Joint/Bone procedures a. Arthrodesis b. Osteotomy 3. Nerve procedures a. Neurectomy 4. Amputations
  • 16.
  • 17. - Reduce spasticity in target muscles Technique: ā€¢ Follows motor ramus until entry point into target muscle Improves ā€¢ Selectivity ā€¢ Widespread partial denervation ā€¢ Durability of results
  • 18. ā€¢ Systematic review: 7 studies, 174 patients ā€¢ Percentage of fascicles ablated between 30-80% ā€¢ Length of neurectomy: 5-10mm ā€¢ Remove end branches vs fascicular selective neurectomy proximally ā€¢ All had improvement in spasticity ā€¢ Recurrence rate: 0-16.1%
  • 19. 17 Stroke 6 received Botox 3 underwent HSN 1 underwent tendon lengthening 22 patients 3 Focal dystonia2 CP ā€¢ 12 Male, 5 Female ā€¢ Mean age 62.9 years ā€¢ Reviewed average 9months post-stroke 2 received Botox 1 underwent HSN 1 received Botox 1 underwent HSN
  • 20. Hyperselective Neurectomy (HSN) Upper limb 1. Biceps 1 2. FCU 1 3. FCR 1 4. FDS 4 5. FPL 2 6. PT 2 Lower limb 1. FDL 2 2. FHL 2 3. Gastrocnemius 1
  • 25. FDS Neurectomy Nerve stimulation for identification of FDS fascicles ā€¢ Interfascicular dissection ā€¢ Select branches for neurectomy (nerve stimulation) ā€¢ Neurectomy (1-2cm): 2 out of 3 branches
  • 26. FPL
  • 27.
  • 28. Right LL: ā€¢ FDL, FHL spasm ā€¢ Severe spasm on certain days ā€¢ Causes clawing of toes and pain ā€¢ Coping with gait fairly well with orthosis ā€¢ FHL and FDL spasticity when he walks
  • 29. FHL
  • 31.
  • 32.
  • 33. Patient Procedure performed Pre- surgery MAS Post-surgery MAS 1 HSN Biceps 3 Biceps 1 2 HSN FDS 3 FPL 2 PT 3 FDL 3 FHL 3 FDS 2 FPL 1 PT 2 FDL 1 FHL 1 3 HSN Tenotomy ā€¢ Abductor hallucis FDS 3 FPL 3 FHL 3 FDL 3 FDS 2 FPL 1 FHL 1 FDL 1 4 (Lengthening) Z-lengthening Fractional FPL 3 FDS 4 FPL 0 FDS 3 0 0.5 1 1.5 2 2.5 3 3.5 Pre Post Average Modified Ashworth Scale Average MAS 56% improvement in spasticity score
  • 34. Patient Procedure performed Hand Function (House) Pre/Post Patient satisfaction (Good/Fair/Poor) 1 HSN biceps 8/8 Good 2 HSN FDS, FPL, PT FDL, FHL 2/2 Poor (UL) Good (LL) 3 HSN FDS, FPL, FHL, FDL Tenotomy ā€¢ Abductor hallucis 1/1 Fair (UL) Good (LL) 4 (Lengthening) Z-lengthening Fractional 8/8 Poor
  • 35. Conclusions ā€¢ Evolving management strategies ā€¢ Simpler assessment instruments ā€¢ Robust patient experience outcome measures ā€¢ More interactions among stroke MDT ā€¢ *Counselling ā€¢ *Education & raise awareness (patients and physicians)
  • 36.
  • 37. Welcome to Singapore for the 2023 APFSSH & APFSHT meeting! www.apfssh2023.org Proposed dates: 17-20 May 2023 (Wed to Saturday) OR 24-27 May 2023 (Wed to Saturday)

Editor's Notes

  1. Result of hyperexcitability of the stretch reflex Secondary to damage to the neurons of the corticospinal tracts, Loss of inhibitory supraspinal influences Characterised by Velocity-dependent increase in tonic stretch reflexes (ā€œmuscle toneā€) With exaggerated deep tendon reflexes Complex problem Need for an integrated care pathway for these patients Post Stroke Spasticity Pathway developed using expert panel Requires MDT approach for optimum treatment
  2. MDTs are seen to be effective in Asian contexts of chronic stroke management, like that of Japanā€™s Stroke Rehabilitation Unit (SRU) in Bobath Memorial Hospital, Osaka. And in Korean contexts as well. No surgeons involved Evidenceā€“ rehab paper
  3. Volition, house , 6 patients received Botox injection 3 patients underwent hyperselective neurectomy in upper limb 1 patient with contractures underwent tendon lengthening procedure
  4. Nerve stimulation
  5. Hand function based on house classn; no improvement
  6. Multidisciplinary team approach ensures seamless process for stroke patients with problems of upper limb spasticity Highly selective neurectomy useful technique to relieve spasticity while preserving function Need for authentic and patient experienced outcome measures Effect for neurectomies Cognitive load in spasticity