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Keep Smiling….!   “ It will help you to grow up in greater happiness & Love for each other." Mother Teresa 1910-1997, Roman Catholic Missionary
Pathology of  Hypertension: Dr. Venkatesh M. Shashidhar. Associate Professor & Head of Pathology
Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Hypertension - Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Regulation of BP: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Etiologic Classification: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Etiology: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathogenesis of Renovascular HTN:  GFR Renin by JGA Angiotensin II Vasoconstriction    P. Resistance Sodium Retention  Blood Volume Aldosterone Hypertension
Malignant Hypertension: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Morphology: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathogenesis of vascular changes. ,[object Object],[object Object],[object Object],[object Object],Ischemia, Aneurysm, Rupture
 
Left Ventricular Hypertrophy: Left Ventricular Hypertrophy
Hyperplastic Arteriolosclerosis: Onion Skin Thickening Of arterioles. Narrow Lumen
Nephrosclerosis in HPTN: Artery Sclerosis Artery Sclerosis PCT hydropic deg.
Nephrosclerosis in HPTN: Artery Sclerosis Glom. Sclerosis Artery Sclerosis PCT hydropic deg.
Necrotizing arteriole: Malignant HPTN Fibrinoid Necrosis Thrombosis
Subarachnoid Haemorrhage: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cerebral Infarction (Stroke) : Haemorrhagic Necrosis
Lacunar Infarct: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Benign  Nephrosclerosis: Leathery Granularity  due to minute scarring
Cerebral Infarction:
Renal Causes : ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Polycystic Kidney ->
Renal Artery stenosis - Atrophy Leathery Granularity Benign Nephrosclerosis
Normal Retina - Fundoscopy
Hypertensive Retinopathy: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Hypertensive Retinopathy: ,[object Object],[object Object],[object Object],[object Object]
G Protien Polymorphisms in Metabolic Syndrome-X ,[object Object]
Conclusions: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Self Assessment Questions: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Pathology of Hypertension