21. Reasons to go with Panels
Easy way to theme nodes
Conditional layouts and content
Combining components
Easy export and version control
Context aware content
Easy deployment
Show front pages + node views from u21denmark2011.com
Show different node views from u21 + different contexts
Point out regional menus from u21 + profile faktaboks view + facility list from aakb.dk
To get that out of the way. Quite an overlap between drupal modules
Panels allow you to make both design and content dependent on context, content/field or user.
Panels give you an easy way of theming nodes with creating and maintaing tons of templates
Panels allow you to easily export your setup and layouts to code and version control it
An easy way of making content - eg. blocks - context aware using ctools.
One way to ease the rollout of new features on production sites
Install panels + views
Create new homepage, create variants of node pages
U21: Node: Profile
Use Panels path
Argument input
Allow settings
Exporting and version controlling panels
Bulk exporter or features