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Malaria
Education
and
Treatment
Presented by Dr. Zoraiz Haider
What is Malaria?
• It is a kind of,
• Fever with or without chills.
• Fever comes in alternate days,
• Then it is called Suspected Malaria.
• Caused by the plasmodium parasite enter
body by bite of Female Mosquito Anopheles.
Symptoms of Malaria?
• 1st sign & symptom of Malaria:
• Suddenly excessive shivering occur
• Chills usually happen
• High fever above 103F.
• Excessive sweating after 2-3 hours & then
temperature turns to normal and it mostly
happen at night on alternate days.
• Dry Cough
Later Symptoms of Malaria
• Headache
• Muscular Fatigue and pain
• Back pain
• Spleen Enlarge
• Nausea & Vomiting
Plasmodium falciparum Malaria
Symptoms
• also called Cerebral or Brain malaria.
• In this condition patient start to show severe
neurological complication and therefore also
have certain epileptic attacks.
• Also has systemic fever occur.
Cause of Malaria?
• Malaria is of different kinds and each type is
caused by the different type of Plasmodium
parasite. i.e
• 1. P. Vivax
• 2. P. falciparum
• 3. P. Malariae
• 4. P. Ovale
Diagnosis of Malaria
• Malaria can be diagnose by several test i.e,
• 1. Peripheral Blood smear test
• 2. Rapid malaria kit test
Physical Examination:
• Patient liver & spleen size enlarge during
examination
• Patient is also anemic if malaria is not treated
for long time.
• Suspected malaria confirm by Lab test:
• Rapid malaria kit test is mostly use b/c it give
result in 20mins to diagnose whether it is,
• 1. Plasmodium vivax
• 2. plasmodium falciparum OR
• 3. Mix malaria
If line appear in front
of,
C = No Malaria(-)
Pv = P. Vivax (-)
Pf = P. falciparum (-)
Rapid malaria kit test
Treatment of Malaria
• Plasmodium treatment depend upon the fact
that patient have which type of plasmodium.
P.vivax & P.falciparum is in India, pakistan and
Bangladesh
• While
• P.Malaria & P.Ovale is mostly in other
countries.
Malaria Types
on basis of Symptoms
• 1. Uncomplicated Malaria:
• Moderate symptoms
• 2. Complicated (Severe) Malaria:
• Severe symptoms
Plasmodium Vivax Malaria treatment
• 1st day: Chloroquine tab orally 10mg/kg
• 2nd day: Chloroquine tab orally 10mg/kg
• Then
• 3rd day: Chloroquine tab orally 5mg/kg
• Addtion to
• Primaquine tab 0.25mg/kg daily upto 14days
• Do not give Chloroquine tab in case of
P.falciparum malaria because they are resistant
to Chloroquine.
• And
• Do Not give primaquine in
• Infants
• Pregnant females and
• G6PD deficiency disorder patients (anemic
symptom).
Other symptomatic treatment
• If you have Fever:
• Paracetamol 500mg after breakfast , lunch and dinner
for about 3- 4 days.
• To treat Vomiting and Nausea:
• Domperidone 10mg (motilium) + pantoprazol 40mg
with empty stomach daily one time in 24hrs for about 7- 10
days.
• If Nausea and Vomiting not treat from above medicine then
take.
• Ondensetron 2mg/1ml IV or IM
when vomiting or nausea (Onden inj)
Plasmodium Falciparum Treatment
• Arceva tab oral:
• It contains (Artemether 80mg and Lumefantrine 480mg)
• 1st Day:
• 1st Dose: Take 1 Tab orally in the morning during breakfast
with milk.
• 2nd Dose: After 1st Dose take other 1 tab after 8 hours with
milk.
• 2nd Day:
• Then next 1-1 tab two times a day up to 2 days.
• Primaquine tab 0.75mg/kg orally as single dose.
• Take this tablet with Milk b/c patient do vomit if take with
water in 80- 90% cases.
If Arceva Tab is not available
• Then take Fansidar in place of Arceva tab.
• Malarest OR Fansidar:
• Sulphadoxine 500mg and Pyrimethamine 25mg (3
tabs) 20 : 1)
• If patient is Above 18 years then, Dose for Malaria:
{Sulphadoxine 500mg and Pyrimethamine 25mg(3
tabs)} Take 3 tabs in one day at same time.
• Also take,
• Artisunate tab 100mg once time in a day,
up to 3 days with it.
Uncomplicated P.Falciparum Treatment
Plasmodium vivax During pregnancy
• Then Chloroquine (Rosechin) is safe in all
trimesters But,
• Primaquine is not safe so patient have to
complete this course after pregnancy and
• Must take Primaquine 0.25mg/kg orally up to
14days to complete eradicate the malaria.
Plasmodium falciparum During
pregnancy
• If patient is in 1st trimester then can be given
quinine tablet but
• if patient in 2nd or 3rd trimester then can be
given
• Artisunate and combination of
• Sulphadoxine and pyrimethamine tab
(Fansidar) orally.
Mix Malaria patient
• In case of Mix malaria,
• 1st treat Plasmodium falsicaprum malaria
and then
• Treat Plasmodium vivax Malaria with
• Primaquine 0.25mg/kg
for 14days
Remember this
• In case of P.Vivax Malaria
• Dose of Primaquine is 0.25mg/kg for 14days.
• And
• In case of P.falciparum Malaria
• Dose of Primaquine is 0.75mg/kg orally as
single dose at 2nd day of treatment.
Diet in Malaria
Prevention in Malaria
Malaria fever and its treatment
Malaria fever and its treatment

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Malaria fever and its treatment

  • 2. What is Malaria? • It is a kind of, • Fever with or without chills. • Fever comes in alternate days, • Then it is called Suspected Malaria. • Caused by the plasmodium parasite enter body by bite of Female Mosquito Anopheles.
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  • 4. Symptoms of Malaria? • 1st sign & symptom of Malaria: • Suddenly excessive shivering occur • Chills usually happen • High fever above 103F. • Excessive sweating after 2-3 hours & then temperature turns to normal and it mostly happen at night on alternate days. • Dry Cough
  • 5. Later Symptoms of Malaria • Headache • Muscular Fatigue and pain • Back pain • Spleen Enlarge • Nausea & Vomiting
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  • 7. Plasmodium falciparum Malaria Symptoms • also called Cerebral or Brain malaria. • In this condition patient start to show severe neurological complication and therefore also have certain epileptic attacks. • Also has systemic fever occur.
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  • 9. Cause of Malaria? • Malaria is of different kinds and each type is caused by the different type of Plasmodium parasite. i.e • 1. P. Vivax • 2. P. falciparum • 3. P. Malariae • 4. P. Ovale
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  • 11. Diagnosis of Malaria • Malaria can be diagnose by several test i.e, • 1. Peripheral Blood smear test • 2. Rapid malaria kit test Physical Examination: • Patient liver & spleen size enlarge during examination • Patient is also anemic if malaria is not treated for long time.
  • 12. • Suspected malaria confirm by Lab test: • Rapid malaria kit test is mostly use b/c it give result in 20mins to diagnose whether it is, • 1. Plasmodium vivax • 2. plasmodium falciparum OR • 3. Mix malaria
  • 13. If line appear in front of, C = No Malaria(-) Pv = P. Vivax (-) Pf = P. falciparum (-) Rapid malaria kit test
  • 14. Treatment of Malaria • Plasmodium treatment depend upon the fact that patient have which type of plasmodium. P.vivax & P.falciparum is in India, pakistan and Bangladesh • While • P.Malaria & P.Ovale is mostly in other countries.
  • 15. Malaria Types on basis of Symptoms • 1. Uncomplicated Malaria: • Moderate symptoms • 2. Complicated (Severe) Malaria: • Severe symptoms
  • 16. Plasmodium Vivax Malaria treatment • 1st day: Chloroquine tab orally 10mg/kg • 2nd day: Chloroquine tab orally 10mg/kg • Then • 3rd day: Chloroquine tab orally 5mg/kg • Addtion to • Primaquine tab 0.25mg/kg daily upto 14days
  • 17. • Do not give Chloroquine tab in case of P.falciparum malaria because they are resistant to Chloroquine. • And • Do Not give primaquine in • Infants • Pregnant females and • G6PD deficiency disorder patients (anemic symptom).
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  • 20. Other symptomatic treatment • If you have Fever: • Paracetamol 500mg after breakfast , lunch and dinner for about 3- 4 days. • To treat Vomiting and Nausea: • Domperidone 10mg (motilium) + pantoprazol 40mg with empty stomach daily one time in 24hrs for about 7- 10 days. • If Nausea and Vomiting not treat from above medicine then take. • Ondensetron 2mg/1ml IV or IM when vomiting or nausea (Onden inj)
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  • 22. Plasmodium Falciparum Treatment • Arceva tab oral: • It contains (Artemether 80mg and Lumefantrine 480mg) • 1st Day: • 1st Dose: Take 1 Tab orally in the morning during breakfast with milk. • 2nd Dose: After 1st Dose take other 1 tab after 8 hours with milk. • 2nd Day: • Then next 1-1 tab two times a day up to 2 days. • Primaquine tab 0.75mg/kg orally as single dose. • Take this tablet with Milk b/c patient do vomit if take with water in 80- 90% cases.
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  • 25. If Arceva Tab is not available • Then take Fansidar in place of Arceva tab. • Malarest OR Fansidar: • Sulphadoxine 500mg and Pyrimethamine 25mg (3 tabs) 20 : 1) • If patient is Above 18 years then, Dose for Malaria: {Sulphadoxine 500mg and Pyrimethamine 25mg(3 tabs)} Take 3 tabs in one day at same time. • Also take, • Artisunate tab 100mg once time in a day, up to 3 days with it.
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  • 30. Plasmodium vivax During pregnancy • Then Chloroquine (Rosechin) is safe in all trimesters But, • Primaquine is not safe so patient have to complete this course after pregnancy and • Must take Primaquine 0.25mg/kg orally up to 14days to complete eradicate the malaria.
  • 31. Plasmodium falciparum During pregnancy • If patient is in 1st trimester then can be given quinine tablet but • if patient in 2nd or 3rd trimester then can be given • Artisunate and combination of • Sulphadoxine and pyrimethamine tab (Fansidar) orally.
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  • 33. Mix Malaria patient • In case of Mix malaria, • 1st treat Plasmodium falsicaprum malaria and then • Treat Plasmodium vivax Malaria with • Primaquine 0.25mg/kg for 14days
  • 34. Remember this • In case of P.Vivax Malaria • Dose of Primaquine is 0.25mg/kg for 14days. • And • In case of P.falciparum Malaria • Dose of Primaquine is 0.75mg/kg orally as single dose at 2nd day of treatment.
  • 36.